Explanipedia

Indications and complications associated with centrifuge-based therapeutic plasma exchange - a retrospective review Open

David S. Warner, Heather J. Duncan, Prakash Gudsoorkar, Manish Anand · 2025

TPE is an extracorporeal treatment modality for managing various renal and non-renal diseases. The study demonstrated that 18.7% of the patients at our center received TPE for conditions in which its role is not yet established, suggesting…

Board of Directors Role in Data Privacy Governance: Making the Transition from Compliance Driven to Good Business Stewardship Open

David S. Warner, Lisa McKee · 2024

Data collection, use, leveraging, and sharing as a business practice and advantage has proliferated over the past decade. Along with this proliferation of data collection is the increase in regulatory activity which continues to morph expo…

Intracarotid Infusion of Redox-Active Manganese Porphyrin, MnTnBuOE-2-PyP5+, following Reperfusion Improves Long-Term, 28-Day Post-Stroke Outcomes in Rats Open

Xuan Li, Weina Duan, Li Du, Dongmei Chu, Peng Wang , et al. · 2023

Endovascular mechanical thrombectomy, combined with a tissue plasminogen activator (t-PA), is efficacious as a standard care for qualifying ischemic stroke patients. However, > 50% of thrombectomy patients still have poor outcomes. Mangane…

Supplementary Material for: Sealed Unilateral Full-Thickness Macular Hole with Amniotic Membrane Graft in a Patient with Alport Syndrome: A Case Report Open

Sayena Jabbehdari, Tetelbom P.S., David S. Warner, Uwaydat S.H. · 2023

We present a case of unilateral full-thickness macular hole (MH) successfully repaired with an amniotic membrane graft in a patient with Alport syndrome. A 58-year-old Asian female with past medical history of Alport syndrome diagnosed at …

SIRT1 Activation Promotes Long-Term Functional Recovery After Subarachnoid Hemorrhage in Rats Open

Dongmei Chu, Xuan Li, Xingguang Qu, Deepti Diwan, David S. Warner , et al. · 2022

Manganese Porphyrin Promotes Post Cardiac Arrest Recovery in Mice and Rats Open

Peng Wang, Ying Li, Baihui Yan, Yang Zhong, Litao Li , et al. · 2022

Introduction Cardiac arrest (CA) and resuscitation induces global cerebral ischemia and reperfusion, causing neurologic deficits or death. Manganese porphyrins, superoxide dismutase mimics, are reportedly able to effectively reduce ischemi…

Sex Differences from in Vivo Single Microglial Cell Isolation after Intracerebral Hemorrhage in Mice Open

Beilei Lei, Yong Ho Kim, Wenjing Qi, Temugin Berta, Anna Covington , et al. · 2022

Development and Evaluation of a Novel Mouse Model of Asphyxial Cardiac Arrest Revealed Severely Impaired Lymphopoiesis After Resuscitation Open

Wei Wang, Ran Li, Wanying Miao, Cody Evans, Liping Lu , et al. · 2021

Background Animal disease models represent the cornerstone in basic cardiac arrest (CA) research. However, current experimental models of CA and resuscitation in mice are limited. In this study, we aimed to develop a mouse model of asphyxi…

Increasing O-GlcNAcylation is neuroprotective in young and aged brains after ischemic stroke Open

Zhuoran Wang, Xuan Li, Ivan Spasojević, Liping Lu, Yuntian Shen , et al. · 2021

Identification of deep coal seam families using machine learning Open

Tauqir Ahmed Moughal, Irina Emelyanova, David S. Warner, Erik C. Dunlop, Mohinudeen Faiz , et al. · 2019

SummarySummaryThe Cooper Basin of Australia is a world-class unconventional gas resource with estimated gas resources of 29.8 trillion cubic feet. However, the production of this gas is challenging as the significant gas resources are loca…

Argon Inhalation for 24 Hours After Onset of Permanent Focal Cerebral Ischemia in Rats Provides Neuroprotection and Improves Neurologic Outcome Open

Shuang Ma, Dongmei Chu, Litao Li, Jennifer Creed, Yu‐Mi Ryang , et al. · 2019

Objectives: We tested the hypothesis that prolonged inhalation of 70% argon for 24 hours after in vivo permanent or temporary stroke provides neuroprotection and improves neurologic outcome and overall recovery after 7 days. Design: Contro…

Novel Modification of Potassium Chloride Induced Cardiac Arrest Model for Aged Mice Open

Huaqin Liu, Zhui Yu, Ying Li, Bin Xu, Baihui Yan , et al. · 2018

Experimental cardiac arrest (CA) in aging research is infrequently studied in part due to the limitation of animal models. We aimed to develop an easily performed mouse CA model to meet this need. A standard mouse KCl-induced CA model usin…

2015 revised Utstein-style recommended guidelines for uniform reporting of data from drowning-related resuscitation Open

Ahamed H. Idris, Joost J.L.M. Bierens, Gavin D. Perkins, Volker Wenzel, Vinay Nadkarni , et al. · 2017

2015 Revised Utstein-Style Recommended Guidelines for Uniform Reporting of Data From Drowning-Related Resuscitation: An ILCOR Advisory Statement Open

Ahamed H. Idris, Joost J.L.M. Bierens, Gavin D. Perkins, Volker Wenzel, Vinay Nadkarni , et al. · 2017

Background— Utstein-style guidelines use an established consensus process, endorsed by the international resuscitation community, to facilitate and structure resuscitation research and publication. The first “Guidelines for Uniform Reporti…

Anesthetic Neuroprotection? It’s Complicated Open

David S. Warner, Huaxin Sheng · 2017

Human papillomavirus-related small cell carcinoma of the oropharynx: a case report and literature review Open

Marcelo Bonomi, Tamjeed Ahmed, David S. Warner, Joshua D. Waltonen, Christopher A. Sullivan , et al. · 2017

Patients with HPV-related cancer of the oropharynx require identification of the small cell variant to optimize therapy and improve outcomes.

Young people, their technology and the fear in schools Open

David S. Warner · 2017

This paper is a conversation piece about the failure of schooling to embrace the technology that 21st century young people use as part of their lives. It directs attention to the fears that schools and probably many adults have of young pe…

Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume Open

Han Kyu Lee, Sehoon Keum, Huaxin Sheng, David S. Warner, Donald C. Lo , et al. · 2016

Risk for ischemic stroke has a strong genetic basis, but heritable factors also contribute to the extent of damage after a stroke has occurred. We previously identified a locus on distal mouse chromosome 7 that contributes over 50% of the …

Activation of the ATF6 branch of the unfolded protein response in neurons improves stroke outcome Open

Zhui Yu, Huaxin Sheng, Shuai Liu, Shengli Zhao, Christopher C. Glembotski , et al. · 2016

Impaired function of the endoplasmic reticulum (ER stress) is a hallmark of many human diseases including stroke. To restore ER function in stressed cells, the unfolded protein response (UPR) is induced, which activates 3 ER stress sensor …

The Effect of Propofol Versus Isoflurane Anesthesia on Human Cerebrospinal Fluid Markers of Alzheimer’s Disease: Results of a Randomized Trial Open

Miles Berger, Jacob W. Nadler, Allan Friedman, David L. McDonagh, Ellen Bennett , et al. · 2016

Background: Preclinical studies have found differential effects of isoflurane and propofol on the Alzheimer’s disease (AD)-associated markers tau, phosphorylated tau (p-tau) and amyloid-β (Aβ). Objective: We asked whether isoflurane and pr…

Physiology Of Drowning: A Review Open

Joost J.L.M. Bierens, Philippe Lunetta, Mike Tipton, David S. Warner · 2016

Drowning physiology relates to two different events: immersion (upper airway above water) and submersion (upper airway under water). Immersion involves integrated cardiorespiratory responses to skin and deep body temperature, including col…

Reporting of Preclinical Research in Anesthesiology Open

James C. Eisenach, David S. Warner, Timothy T. Houle · 2016

ENETS Newsletter Open

Katharina Biermann, Richard A. Feelders, Leo J. Hofland, Wouter W. de Herder, Roxanne C.S. van Adrichem , et al. · 2016

Video training and certification program improves reliability of postischemic neurologic deficit measurement in the rat Open

Hideki Taninishi, Molly Pearlstein, Huaxin Sheng, Miwa Izutsu, Rafael E Chaparro , et al. · 2015

Scoring systems are used to measure behavioral deficits in stroke research. Video-assisted training is used to standardize stroke-related neurologic deficit scoring in humans. We hypothesized that a video-assisted training and certificatio…

IMPROVING BALANCE IN PATIENTS WITH DIABETIC PERIPHERAL NEUROPATHY USING ELECTRICAL STIMULATION Open

G. S. Grewal, Saman Parvaneh, Ross G. Menzies, Tala Talal, David G. Armstrong , et al. · 2015

problem-solving support.Over 30 evidence-based (i.e.RCT) programs are currently implemented across this country.This meta-analysis focus on how these programs are used to target frail populations of older adults with MCC.Programs are relav…

Intra-operative hydroxyethyl starch is not associated with post-craniotomy hemorrhage Open

James A Feix, C Andrew Peery, Tong J. Gan, David S. Warner, Michael L. James , et al. · 2015

Sustained Functional Improvement by Hepatocyte Growth Factor-Like Small Molecule BB3 after Focal Cerebral Ischemia in Rats and Mice Open

Rafael E Chaparro, Miwa Izutsu, Toshihiro Sasaki, Huaxin Sheng, Yi Zheng , et al. · 2015

Hepatocyte growth factor (HGF), efficacious in preclinical models of acute central nervous system injury, is burdened by administration of full-length proteins. A multiinstitutional consortium investigated the efficacy of BB3, a small mole…

CCDC 1414764: Experimental Crystal Structure Determination Open

David S. Warner, Christian Limberg, Fabio J. Oldenburg, B. Braun · 2015

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

David S. Warner YOU? Author Swipe