Explanipedia

Androstadienone sensitivity is associated with attention to emotions, social interactions, and sexual behavior in older U.S. adults Open

David W. Kern, Gabriel T. Kaufmann, Tom A. Hummer, L. Philip Schumm, Kristen Wroblewski , et al. · 2023

Δ 4,16-androstadien-3-one (androstadienone) is a putative human pheromone often linked to sexual attraction in young adults, although specific associations with sexual behavior are not yet established. Androstadienone also serves a broader…

Table of Contents Open

R. M. Williams, Douglas K. Stuart, Mark E. Schmitt, Katrin Althans, David W. Kern , et al. · 2023

Olfaction Is Associated With Sexual Motivation and Satisfaction in Older Men and Women Open

Jesse K. Siegel, Sunny Y. Kung, Kristen Wroblewski, David W. Kern, Martha K. McClintock , et al. · 2021

Olfactory dysfunction in older U.S. adults is associated with decreased sexual motivation and emotional satisfaction, potentially due to evolutionarily-conserved neurological links between olfaction and sexuality. Siegel JK, Kung SY, Wrobl…

IL-1Rahigh-IL-4low-IL-13low: A Novel Plasma Cytokine Signature Associated with Olfactory Dysfunction in Older US Adults Open

Eli P. Darnell, Kristen Wroblewski, Kristina L. Pagel, David W. Kern, Martha K. McClintock , et al. · 2020

Inflammation has been implicated in physical frailty, but its role in sensory impairment is unclear. Given that olfactory impairment predicts dementia and mortality, determining the role of the immune system in olfactory dysfunction would …

Individual neural transfer function affects the prediction of subjective depth of focus Open

Alexander Leube, Tim Schilling, Arne Ohlendorf, David W. Kern, Alex Ochakovski , et al. · 2018

Cognitive Function and its Risk Factors Among Older US Adults Living at Home Open

William Dale, Ashwin Kotwal, Joseph W. Shega, L. Philip Schumm, David W. Kern , et al. · 2018

Background: The Montreal Cognitive Assessment (MoCA) has not been administered to a representative national sample, precluding comparison of patient scores to the general population and for risk factor identification. Methods: A validated …

Olfactory Dysfunction Predicts Subsequent Dementia in Older U.S. Adults Open

Dara R. Adams, David W. Kern, Kristen Wroblewski, Martha K. McClintock, William Dale , et al. · 2017

Objectives To investigate the relationship between olfactory dysfunction and subsequent diagnosis of dementia. Design Longitudinal study of a population representative of U.S. older adults. Setting Home interviews (National Social Life, He…

Global Sensory Impairment Predicts Morbidity and Mortality in Older U.S. Adults Open

Jayant M. Pinto, Kristen Wroblewski, Megan Huisingh‐Scheetz, Camil Correia, Kevin Lopez , et al. · 2017

Objectives To evaluate global sensory impairment ( GSI , an integrated measure of sensory dysfunction) as a predictor of physical function, cognition, overall health, and mortality. Design Prospective study. Setting The National Social Lif…

Radial averaging of the optical modulation transfer function and its impact on image quality Open

Alexander Leube, David W. Kern, Arne Ohlendorf, Siegfried Wahl · 2017

Sleep and Olfaction among Older Adults Open

V Eloesa McSorley, Jayant M. Pinto, L. Philip Schumm, Kristen Wroblewski, David W. Kern , et al. · 2017

Background: Sleep and olfaction are both critical physiological processes that tend to worsen with age. Decline in olfaction can be an early indicator of neurodegenerative diseases, whereas poor sleep quality is associated wi…

Contents Vol. 48, 2017 Open

Jasem Al-Hashel, Samar Farouk Ahmed, Raed Alroughani, Scott B. Patten, Ruth Ann Marrie , et al. · 2017

Factors Associated with Inaccurate Self-Reporting of Olfactory Dysfunction in Older US Adults Open

Dara R. Adams, Kristen Wroblewski, David W. Kern, Michael Kozloski, William Dale , et al. · 2016

Self-reported olfactory function has poor sensitivity (i.e., people with measured olfactory dysfunction are unlikely to accurately report it). We aimed to identify factors associated with lack of awareness of smell dysfunction. Objective o…

Fine particulate matter exposure and olfactory dysfunction among urban-dwelling older US adults Open

Gaurav S. Ajmani, Helen Suh, Kristen Wroblewski, David W. Kern, L. Philip Schumm , et al. · 2016

Nitrogen dioxide pollution exposure is associated with olfactory dysfunction in older U.S. adults Open

Dara R. Adams, Gaurav S. Ajmani, Vivian C. Pun, Kristen Wroblewski, David W. Kern , et al. · 2016

Background Olfactory dysfunction has profound effects on quality of life, physical and social function, and mortality itself. Nitrogen dioxide (NO 2 ) is a pervasive air pollutant that is associated with respiratory diseases. Given the olf…

Global Sensory Impairment in Older Adults in the United States Open

Camil Correia, Kevin Lopez, Kristen Wroblewski, Megan Huisingh‐Scheetz, David W. Kern , et al. · 2016

Objectives To determine whether there may be a common mechanism resulting in global sensory impairment of the five classical senses (vision, smell, hearing, touch, and taste) in older adults. Design Representative, population‐based study. …

Effect of olfactory ability on the mean predicted probability of 5-year mortality, adjusting for age (A) and composite mortality risk score composed of all variables in Model C except olfaction (B). Open

Jayant M. Pinto, Kristen Wroblewski, David W. Kern, L. Philip Schumm, Martha K. McClintock · 2015

At the 75^th percentile of composite mortality risk, anosmia increases the average probability of death to 0.39 from 0.16 for normal smellers.

The Rate of Age-Related Olfactory Decline Among the General Population of Older U.S. Adults Open

Jayant M. Pinto, Kristen Wroblewski, David W. Kern, L. Philip Schumm, Martha K. McClintock · 2015

The rate of olfactory decline increases with age and is greater among men than women despite adjusting for differences in psychosocial and health conditions, indicating physiologic factors as drivers. African Americans are more likely to e…

Olfactory Thresholds of the U.S. Population of Home-Dwelling Older Adults: Development and Validation of a Short, Reliable Measure Open

David W. Kern, L. Philip Schumm, Kristen Wroblewski, Jayant M. Pinto, Thomas Hummel , et al. · 2015

Current methods of olfactory sensitivity testing are logistically challenging and therefore infeasible for use in in-home surveys and other field settings. We developed a fast, easy and reliable method of assessing olfactory thresholds, an…

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