David Weisman
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View article: Ownership and Perceived Usefulness of Digital Health Tools (DHT) for Health Promotion Among Individuals with Rheumatologic Diseases in the United States
Ownership and Perceived Usefulness of Digital Health Tools (DHT) for Health Promotion Among Individuals with Rheumatologic Diseases in the United States Open
Females, individuals <65 years, and those with higher annual income had higher odds of health applications usage. DHT facilitated better communication between patients with RD and healthcare providers. DHT tailored for RD are readily avail…
View article: Diagnostic efficacy of computed tomography angiography for acute gastrointestinal bleeding
Diagnostic efficacy of computed tomography angiography for acute gastrointestinal bleeding Open
Background and aims: Computed tomography angiography (CTA) is the radiologic test for acute gastrointestinal bleeding (GIB). We aimed to (1) identify the clinical factors associated with (a) positive CTA findings, (b) positive esophagogast…
View article: Outcome comparison in Hospitalized COVID-19 Patients with and without AKI
Outcome comparison in Hospitalized COVID-19 Patients with and without AKI Open
AKI in hospitalized patients with COVID-19 was associated with higher mortality rate, need for intubation and ICU admission compared to COVID-19 patients without AKI group.
View article: Randomized Phase II Study of the Safety and Efficacy of Semorinemab in Participants With Mild-to-Moderate Alzheimer Disease: Lauriet
Randomized Phase II Study of the Safety and Efficacy of Semorinemab in Participants With Mild-to-Moderate Alzheimer Disease: Lauriet Open
The Lauriet study is registered on ClinicalTrials.gov, NCT03828747, and EudraCT 2018-003398-87.
View article: Diagnostic dilemma: drug-induced vasculitis versus systemic vasculitis
Diagnostic dilemma: drug-induced vasculitis versus systemic vasculitis Open
Drug-induced vasculitis can rarely cause inflammation and necrosis of blood vessel walls of both kidney and lung tissue. Diagnosis is challenging because of the lack of difference between systemic and drug-induced vasculitis in clinical pr…
View article: Spontaneous retroperitoneal hematoma in vitamin C deficiency
Spontaneous retroperitoneal hematoma in vitamin C deficiency Open
Retroperitoneal hematoma is rare but potentially life-threatening. It is commonly caused by traumatic or iatrogenic vascular injury, retroperitoneal neoplasm, coagulopathy, chronic anticoagulation, or fibrinolytic therapy. However, retrope…
View article: Obesity and COVID-19 Outcomes in a Primarily Black Population
Obesity and COVID-19 Outcomes in a Primarily Black Population Open
Studies have noted higher COVID-19 mortality with more severe obesity in populations that included a small percentage of Black patients.
View article: The Effect of Race and Socioeconomic Status on Hospitalized Patients with COVID-19 Infection
The Effect of Race and Socioeconomic Status on Hospitalized Patients with COVID-19 Infection Open
Our cohort of patients in a large mid-Atlantic health system showed that there was no statistically significant difference between race or socioeconomic status and COVID-19 related inpatient mortality. However, Black patients and individua…
View article: Ruptured Sinus of Valsalva Aneurysm in Apert Syndrome: Case Report
Ruptured Sinus of Valsalva Aneurysm in Apert Syndrome: Case Report Open
Ruptured SOVA is a quite rare but serious condition that can cause life-threatening complications. In this case, SOVA occurred in a patient with Apert syndrome. The case may suggest that these two conditions may be related through the FGFR…
View article: Lamotrigine-associated hemophagocytic lymphohistiocytosis
Lamotrigine-associated hemophagocytic lymphohistiocytosis Open
Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening disorder of excessive immune activation. It is mostly seen in the paediatric population and is rarely observed in adults. HLH can be inherited or acquired and is commo…
View article: A rare case of spontaneous tumor lysis syndrome in multiple myeloma
A rare case of spontaneous tumor lysis syndrome in multiple myeloma Open
Spontaneous tumor lysis syndrome is an uncommon oncologic emergency. It occurs when a massive number of malignant cells release their contents to the blood stream without previous cancer treatment. TLS carries a mortality rate exceeding 15…
View article: ACE inhibitor angioedema: characterization and treatment versus non-ACE angioedema in acute hospitalized patients
ACE inhibitor angioedema: characterization and treatment versus non-ACE angioedema in acute hospitalized patients Open
Background: ACE angioedema has not been characterized in comparison with angioedema from other causes in acute hospitalized patients. Methods: We retrospectively compared ACE-angioedema and non-ACE angioedema patients from January 2013 to …
View article: Fatal intoxication with <i>N</i>-ethylpentylone: a case report
Fatal intoxication with <i>N</i>-ethylpentylone: a case report Open
Synthetic cathinones represent the latest genre of new drugs of abuse, which are increasing in popularity in part because they are readily available and because they are not detected by routine drug testing. They provide a cheaper substitu…
View article: A Resident Initiative Improves Hepatitis C Screening Rates in Primary Care Clinics
A Resident Initiative Improves Hepatitis C Screening Rates in Primary Care Clinics Open
Background Electronic reminders for clinical patient counseling have proven to be an effective response to national recommendations to increase risk factor and birth cohort hepatitis C virus (HCV) screening. It is not known whether a resid…
View article: Permeable Reactive Barriers Designed To Mitigate Eutrophication Alter Bacterial Community Composition and Aquifer Redox Conditions
Permeable Reactive Barriers Designed To Mitigate Eutrophication Alter Bacterial Community Composition and Aquifer Redox Conditions Open
Permeable reactive barriers (PRBs) consist of a labile carbon source that is positioned to intercept nitrate-laden groundwater to prevent eutrophication. Decomposition of carbon in the PRB drives groundwater anoxic, fostering microbial den…
View article: Amyloid-β <sup>11</sup> C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials
Amyloid-β <sup>11</sup> C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials Open
The (11)C-PiB-PET imaging results demonstrated reduction of fibrillar Aβ accumulation in patients with Alzheimer disease treated with bapineuzumab; however, as no clinical benefit was observed, the findings are consistent with the hypothes…
View article: Toxicity Mechanisms Identification via Gene Set Enrichment Analysis of Time-Series Toxicogenomics Data: Impact of Time and Concentration
Toxicity Mechanisms Identification via Gene Set Enrichment Analysis of Time-Series Toxicogenomics Data: Impact of Time and Concentration Open
The advance in high-throughput "toxicogenomics" technologies, which allows for concurrent monitoring of cellular responses globally upon exposure to chemical toxicants, presents promises for next-generation toxicity assessment. It is recog…