David Youens
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Author Swipe
View article: Guarantee-time bias in modelling time-dependent exposure and competing risk events: an application in examining the relationship between use of calcium channel blockers and breast cancer
Guarantee-time bias in modelling time-dependent exposure and competing risk events: an application in examining the relationship between use of calcium channel blockers and breast cancer Open
ObjectivesIncorrect handling of a time-dependent exposure can introduce guarantee-time bias (GTB), which leads to a spurious survival advantage in favour of the exposure group. We explore available approaches and apply them to examine the …
View article: Estimation of the Duration of Antihypertensive Prescriptions: Validation of a Data‐Driven Approach Using Rotterdam Study Data
Estimation of the Duration of Antihypertensive Prescriptions: Validation of a Data‐Driven Approach Using Rotterdam Study Data Open
Objectives Administrative medicine dispensing data often omit prescribed duration, which is important for research on adherence or other pharmacoepidemiological topics. While the reverse waiting time distribution (rWTD) method has been wid…
View article: Temporal trends in concordance between ICD-coded and cardiac biomarker-classified hospitalisation rates for acute coronary syndromes: a linked hospital and biomarker data study
Temporal trends in concordance between ICD-coded and cardiac biomarker-classified hospitalisation rates for acute coronary syndromes: a linked hospital and biomarker data study Open
Background Since 2000, the definition of myocardial infarction (MI) has evolved with reliance on cardiac troponin (cTn) tests. The implications of this change on trends of acute coronary syndrome (ACS) subtypes obtained from routinely coll…
View article: Assessing the feasibility of anticholinergic burden scales and measures in administrative data: A systematic review
Assessing the feasibility of anticholinergic burden scales and measures in administrative data: A systematic review Open
This review emphasizes the importance of adaptable and robust tools that can work well with administrative data to ensure patient safety and better health outcomes, given the ongoing evolution of anticholinergic medications. The findings o…
View article: Demonstrating the use of population level data to investigate trends in the rate, radiation dose and cost of Computed Tomography across clinical groups: Are there any areas of concern?
Demonstrating the use of population level data to investigate trends in the rate, radiation dose and cost of Computed Tomography across clinical groups: Are there any areas of concern? Open
Introduction Increases in computed tomography (CT) use may not always reflect clinical need or improve outcomes. This study aimed to demonstrate how population level data can be used to identify variations in care between patient groups, b…
View article: Association between long-term use of calcium channel blockers (CCB) and the risk of breast cancer: a retrospective longitudinal observational study protocol
Association between long-term use of calcium channel blockers (CCB) and the risk of breast cancer: a retrospective longitudinal observational study protocol Open
Introduction Calcium channel blockers (CCB), a commonly prescribed antihypertensive (AHT) medicine, may be associated with increased risk of breast cancer. The proposed study aims to examine whether long-term CCB use is associated with the…
View article: Use of CT, ED presentation and hospitalisations 12 months before and after a diagnosis of cancer in Western Australia: a population-based retrospective cohort study
Use of CT, ED presentation and hospitalisations 12 months before and after a diagnosis of cancer in Western Australia: a population-based retrospective cohort study Open
Objective To examine the use of CT, emergency department (ED)-presentation and hospitalisation and in 12 months before and after a diagnosis of cancer. Design Population-based retrospective cohort study. Setting West Australian linked admi…
View article: Patterns of computed tomography utilisation in injury management: latent classes approach using linked administrative data in Western Australia
Patterns of computed tomography utilisation in injury management: latent classes approach using linked administrative data in Western Australia Open
Purpose Whilst computed tomography (CT) imaging has been a vital component of injury management, its increasing use has raised concern regarding ionising radiation exposure. This study aims to identify latent classes (underlying patterns) …
View article: Temporal trends in acute coronary syndrome hospitalisation rates: a comparison of administrative diagnosis coding and cardiac biomarker testing
Temporal trends in acute coronary syndrome hospitalisation rates: a comparison of administrative diagnosis coding and cardiac biomarker testing Open
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Victor Chang Cardiac Research Institute. Background/aims Accurate monitoring of trends in acute coronary syndromes (ACS) provides important information o…
View article: Computed Tomography Angiography for Detection of Pulmonary Embolism in Western Australia Shows Increasing Use with Decreasing Diagnostic Yield
Computed Tomography Angiography for Detection of Pulmonary Embolism in Western Australia Shows Increasing Use with Decreasing Diagnostic Yield Open
(1) Background: Pulmonary embolism (PE) can be fatal. Computed tomography pulmonary angiography (CTPA) can accurately diagnose PE, but it should be used only when reasonable pre-test probability exists. Overtesting with CTPA exposes patien…
View article: Supplementary Material for: Differing definitions of first-ever stroke influence incidence estimates more than trends: a study using linked administrative data
Supplementary Material for: Differing definitions of first-ever stroke influence incidence estimates more than trends: a study using linked administrative data Open
Introduction Researchers apply varying definitions when measuring stroke incidence using administrative data. We aimed to investigate the sensitivity of incidence estimates to varying definitions of stroke and lookback periods, and to prov…
View article: Supplementary Material for: Differing definitions of first-ever stroke influence incidence estimates more than trends: a study using linked administrative data
Supplementary Material for: Differing definitions of first-ever stroke influence incidence estimates more than trends: a study using linked administrative data Open
Introduction Researchers apply varying definitions when measuring stroke incidence using administrative data. We aimed to investigate the sensitivity of incidence estimates to varying definitions of stroke and lookback periods, and to prov…
View article: Trend in CT utilisation and its impact on length of stay, readmission and hospital mortality in Western Australia tertiary hospitals: an analysis of linked administrative data 2003–2015
Trend in CT utilisation and its impact on length of stay, readmission and hospital mortality in Western Australia tertiary hospitals: an analysis of linked administrative data 2003–2015 Open
Objective High use of CT scanning has raised concern due to the potential ionising radiation exposure. This study examined trends of CT during admission to tertiary hospitals and its associations with length of stay (LOS), readmission and …
View article: Association of regulatory body actions and subsequent media coverage with use of services in a fee-for-service system: a longitudinal cohort study of CT scanning in Australia
Association of regulatory body actions and subsequent media coverage with use of services in a fee-for-service system: a longitudinal cohort study of CT scanning in Australia Open
Objective The professional service review (PSR) is an Australian Government agency aiming to reduce inappropriate practices funded via Medicare, Australia’s public insurer. Our objective was to examine changes in CT following the 2008–2009…
View article: Associations between regular GP contact, diabetes monitoring and glucose control: an observational study using general practice data
Associations between regular GP contact, diabetes monitoring and glucose control: an observational study using general practice data Open
Objective Continuity and regularity of general practitioner (GP) contacts are associated with reduced hospitalisation in type 2 diabetes (T2DM). We assessed associations of these GP contact patterns with intermediate outcomes reflecting pa…
View article: The use of computed tomography in the management of injury in tertiary emergency departments in Western Australia: Evidence of overtesting?
The use of computed tomography in the management of injury in tertiary emergency departments in Western Australia: Evidence of overtesting? Open
Background This study investigated trends in computed tomography (CT) utilization across different triage categories of injury presentations to tertiary emergency departments (EDs) and associations with diagnostic yield measured by injury …
View article: Regularity of contact with general practitioners and diabetes-related hospitalisation through a period of policy change: A retrospective cohort study
Regularity of contact with general practitioners and diabetes-related hospitalisation through a period of policy change: A retrospective cohort study Open
Background This study evaluated changes in regularity of general practitioner (GP) contact (the pattern of visits over time) and the impact of regularity on diabetes-related hospitalisation following introduction of care co-ordination ince…
View article: Associations Between Regularity of General Practitioner Contacts and Adherence to Statin Therapy
Associations Between Regularity of General Practitioner Contacts and Adherence to Statin Therapy Open
IntroductionResearch has demonstrated continuity and regularity of general practitioner (GP) contacts to be associated with reduced hospitalisations and emergency department (ED) presentations. Opportunities for improved medication managem…
View article: Using general practice clinical information system data for research: the case in Australia
Using general practice clinical information system data for research: the case in Australia Open
General practice is often a patient’s first point of contact with the health system and the gateway to specialist services. In Australia different aspects of the health system are managed by the Commonwealth Government and individual state…
View article: Association between continuity of provider-adjusted regularity of general practitioner (GP) contact and diabetes-related hospitalisation: A data linkage study combining survey and administrative data
Association between continuity of provider-adjusted regularity of general practitioner (GP) contact and diabetes-related hospitalisation: A data linkage study combining survey and administrative data Open
Background and rationale We have previously reported decreased rates and costs of diabetes-related hospitalisations with increasing regularity of general practitioner (GP) contact. However previous work has not adjusted for continuity of p…
View article: Association between continuity of provider-adjusted regularity of general practitioner contact and unplanned diabetes-related hospitalisation: a data linkage study in New South Wales, Australia, using the 45 and Up Study cohort
Association between continuity of provider-adjusted regularity of general practitioner contact and unplanned diabetes-related hospitalisation: a data linkage study in New South Wales, Australia, using the 45 and Up Study cohort Open
Objective To assess the association between continuity of provider-adjusted regularity of general practitioner (GP) contact and unplanned diabetes-related hospitalisation or emergency department (ED) presentation. Design Cross-sectional st…
View article: Assessing the cost‐effectiveness of RT Prepare: A radiation therapist–delivered intervention for reducing psychological distress prior to radiotherapy
Assessing the cost‐effectiveness of RT Prepare: A radiation therapist–delivered intervention for reducing psychological distress prior to radiotherapy Open
Objective To determine the cost‐effectiveness of RT Prepare in reducing breast cancer patients' psychological distress before treatment, compared with usual care. Methods RT Prepare, an intervention involving patient education and support …
View article: Regularity of contact with GPs: Measurement approaches to improve valid associations with hospitalization
Regularity of contact with GPs: Measurement approaches to improve valid associations with hospitalization Open
Background Studies examine longitudinal continuity of GP contact though few consider ‘regularity of GP contact’, i.e., the dispersion of contacts over time. Increased regularity may indicate planned ongoing care. Current measures of regula…
View article: Regular General Practitioner contact - analysis of methods for measurement using administrative data
Regular General Practitioner contact - analysis of methods for measurement using administrative data Open
IntroductionThere is a small body of literature examining the relationship between “regularity” of contact with General Practitioners (GPs), i.e. the pattern of visits over time, and health outcomes. Methods previously used to measure regu…
View article: Evaluating the impact of timing of initiation of community-based palliative care on use and cost of unplanned acute care services at the end of life: A study using linked hospital and community based provider service data
Evaluating the impact of timing of initiation of community-based palliative care on use and cost of unplanned acute care services at the end of life: A study using linked hospital and community based provider service data Open
IntroductionExpected time to death is often used to determine eligibility to publicly funded community-based palliative care (CPC) because most acute care costs in the end-of-life period are incurred immediately prior death. We know CPC us…