Davide Bertuzzo
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View article: Late Response to Anti-CGRP Monoclonal Antibodies in Migraine
Late Response to Anti-CGRP Monoclonal Antibodies in Migraine Open
Half of nonresponders to anti-CGRP mAbs at 12 weeks are indeed late responders. Efficacy of anti-CGRP mAbs should be assessed at 24 weeks while treatment duration should be extended beyond 12 months.
View article: Efficacy of rituximab in anti‐myelin‐associated glycoprotein demyelinating polyneuropathy: Clinical, hematological and neurophysiological correlations during 2 years of follow‐up
Efficacy of rituximab in anti‐myelin‐associated glycoprotein demyelinating polyneuropathy: Clinical, hematological and neurophysiological correlations during 2 years of follow‐up Open
Background and purpose We evaluated the clinical and neurophysiological efficacy of rituximab (RTX) in a neurophysiologically homogeneous group of patients with monoclonal gammopathy and immunoglobulin M (IgM) anti‐myelin‐associated glycop…
View article: Rapid response to galcanezumab and predictive factors in chronic migraine patients: A 3‐month observational, longitudinal, cohort, multicenter, Italian real‐life study
Rapid response to galcanezumab and predictive factors in chronic migraine patients: A 3‐month observational, longitudinal, cohort, multicenter, Italian real‐life study Open
Background and purpose A rapid response to preventive therapy is of pivotal importance in severely disabled patients with chronic migraine (CM) and diverse preventive treatment failures. This prospective, observational, multicenter real‐li…
View article: Droplet Digital PCR Assay for <i>MYD88</i><sup><i>L265P</i></sup>: Clinical Applications in Waldenström Macroglobulinemia
Droplet Digital PCR Assay for <i>MYD88</i><sup><i>L265P</i></sup>: Clinical Applications in Waldenström Macroglobulinemia Open
Waldenström Macroglobulinemia (WM) is defined by the presence of an indolent lymphoplasmacytic lymphoma (LPL) (monoclonal lymphocytes, lymphoplasmacytes and plasma cells (PC) in the bone marrow (BM)) and monoclonal IgM protein secretion.1,…
View article: Secular Trends of Amyotrophic Lateral Sclerosis
Secular Trends of Amyotrophic Lateral Sclerosis Open
During the 1995 to 2014 period, the crude and adjusted incidences of ALS increased in Piemonte and Valle d'Aosta, mostly in women. The APC model revealed that the increase of ALS incidence is attributable to a birth cohort effect in women,…
View article: Common polymorphisms of <i>chemokine (C‐X3‐C motif) receptor 1</i> gene modify amyotrophic lateral sclerosis outcome: A population‐based study
Common polymorphisms of <i>chemokine (C‐X3‐C motif) receptor 1</i> gene modify amyotrophic lateral sclerosis outcome: A population‐based study Open
Introduction : In the brain, the chemokine (C‐X3‐C motif) receptor 1 ( 1CX3CR1 ) gene is expressed only by microglia, where it acts as a key mediator of the neuron–microglia interactions. We assessed whether the 2 common polymorphisms of t…