Davide Di Vece
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View article: Safety and effectiveness of left atrial appendage occlusion in patients with atrial fibrillation and high bleeding risk: a cardinality-matched comparison with direct oral anticoagulation on long-term stroke and bleeding rates
Safety and effectiveness of left atrial appendage occlusion in patients with atrial fibrillation and high bleeding risk: a cardinality-matched comparison with direct oral anticoagulation on long-term stroke and bleeding rates Open
STUDY AIMS: Left atrial appendage occlusion (LAAO) is an accepted alternative stroke prevention strategy for patients with atrial fibrillation (AF) and contraindications to oral anticoagulation despite the lack of randomised data in this p…
View article: Diagnostic performance of coronary CT angiography to diagnose acute spontaneous coronary artery dissection
Diagnostic performance of coronary CT angiography to diagnose acute spontaneous coronary artery dissection Open
Coronary CTA has a poor sensitivity for the diagnosis of SCAD, while specificity is high irrespective of SCAD location. Patients with coronary CTA positive for SCAD might be deferred from ICA after careful consideration and when conservati…
View article: Cocaine-induced acute myocardial infarction: angiographic features and outcomes
Cocaine-induced acute myocardial infarction: angiographic features and outcomes Open
Background Cocaine is a global health burden and the cause of a significant number of emergency department consultations. Its association with acute myocardial infarction (AMI) is known, however, data are still rare. The aim of this study …
View article: Increased Risk of Cardiovascular Events After Coronary Interventions in Inflammatory Bowel Disease: A Nationwide Matched Cohort Study
Increased Risk of Cardiovascular Events After Coronary Interventions in Inflammatory Bowel Disease: A Nationwide Matched Cohort Study Open
Background Inflammatory bowel diseases ( IBD ) have been associated with an increased long‐term risk of coronary artery disease due to chronic systemic inflammation. Aim To evaluate the risk of major adverse cardiovascular events (MACE) af…
View article: Myocardial Late Enhancement With Photon-Counting Detector CT in Spontaneous Coronary Artery Dissection
Myocardial Late Enhancement With Photon-Counting Detector CT in Spontaneous Coronary Artery Dissection Open
Objectives Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome and myocardial infarction. Accurate diagnosis is crucial for appropriate management. This study aimed to compare late enhancement (LE) imag…
View article: Machine learning in cardiovascular risk assessment: Towards a precision medicine approach
Machine learning in cardiovascular risk assessment: Towards a precision medicine approach Open
Cardiovascular diseases remain the leading cause of global morbidity and mortality. Validated risk scores are the basis of guideline‐recommended care, but most scores lack the capacity to integrate complex and multidimensional data. Limita…
View article: Inflammation-Driven Plaque Erosion in Atherosclerosis: A Focus on Complement System Pathways
Inflammation-Driven Plaque Erosion in Atherosclerosis: A Focus on Complement System Pathways Open
View article: Reply to “Reevaluating thromboprophylaxis in COVID-19 outpatients: the case for a targeted, risk-based approach”
Reply to “Reevaluating thromboprophylaxis in COVID-19 outpatients: the case for a targeted, risk-based approach” Open
View article: Clinical characteristics and outcomes in takotsubo syndrome -Review of insights from the InterTAK Registry-
Clinical characteristics and outcomes in takotsubo syndrome -Review of insights from the InterTAK Registry- Open
Takotsubo syndrome (TTS) is a complex cardiovascular condition characterized by transient left and/or right ventricular dysfunction in the absence of a coronary artery culprit lesion. The InterTAK registry, a large international collaborat…
View article: Association of sodium–glucose cotransporter-2 inhibitors with mortality across the spectrum of myocardial infarction: a systematic review and meta-analysis
Association of sodium–glucose cotransporter-2 inhibitors with mortality across the spectrum of myocardial infarction: a systematic review and meta-analysis Open
View article: The Role of Impella in Cardiogenic Shock Complicated by an Acute Myocardial Infarction: A Meta-Analysis
The Role of Impella in Cardiogenic Shock Complicated by an Acute Myocardial Infarction: A Meta-Analysis Open
Background: Emerging evidence suggests the role of mechanical circulatory support (MCS) devices in the therapy of refractory cardiogenic shock (CS). However, largerandomized trials addressing the role of Impella in the therapy of infarct-a…
View article: Effects of sodium–glucose co‐transporter inhibitors on individual clinical endpoints and quality of life
Effects of sodium–glucose co‐transporter inhibitors on individual clinical endpoints and quality of life Open
Aims Sodium–glucose co‐transporter inhibitors (SGLTis) have cardiovascular protective effects. We aimed to assess the effects of SGLTis on individual hard clinical endpoints and quality of life (QoL) in patients with cardiovascular risk fa…
View article: Primary thromboprophylaxis in ambulatory symptomatic patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials
Primary thromboprophylaxis in ambulatory symptomatic patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials Open
Thromboprophylaxis in symptomatic COVID-19 outpatients led to reduction in venous thromboembolism risk, with no impact on hospitalization or death. However, the overall low absolute risk reduction may not support its routine use.
View article: Clinical course of pregnancy-associated spontaneous coronary artery dissection: a case series
Clinical course of pregnancy-associated spontaneous coronary artery dissection: a case series Open
Background Spontaneous coronary artery dissection (SCAD) is the most important cause of acute coronary syndromes during pregnancy and in the post-partum period and involves a spontaneous intimal tear or intramural haematoma of a coronary a…
View article: Cardiogenic shock in takotsubo syndrome: etiology and treatment
Cardiogenic shock in takotsubo syndrome: etiology and treatment Open
Takotsubo syndrome (TTS) can mimic acute coronary syndrome despite being a distinct disease. While typically benign, TTS can lead to serious complications like cardiogenic shock. Cardiogenic shock occurs in 1–20% of TTS cases. Various mech…
View article: Cardiac biomarkers for diagnosing Takotsubo syndrome
Cardiac biomarkers for diagnosing Takotsubo syndrome Open
In this study, involving patients from the world’s largest cohort of TTS patients, the efficacy of biomarker ratios in distinguishing TTS from ACS was found to be only moderately successful, with AUC values ranging from 0.5 to 0.8. Despite…
View article: Effect of SGLT-2 inhibitors on arrhythmia events: insight from an updated secondary analysis of > 80,000 patients (the SGLT2i—Arrhythmias and Sudden Cardiac Death)
Effect of SGLT-2 inhibitors on arrhythmia events: insight from an updated secondary analysis of > 80,000 patients (the SGLT2i—Arrhythmias and Sudden Cardiac Death) Open
Objective We aimed to assess the effect of SGLT2i on arrhythmias by conducting a meta-analysis using data from randomized controlled trials(RCTs). Background Sodium-glucose co-transporter 2 inhibitors (SGLT2i) have shown cardioprotective e…
View article: A novel score to predict in-hospital mortality for patients with acute coronary syndrome and out-of-hospital cardiac arrest: the FACTOR study
A novel score to predict in-hospital mortality for patients with acute coronary syndrome and out-of-hospital cardiac arrest: the FACTOR study Open
Introduction Acute coronary syndromes (ACS) represent a substantial global healthcare challenge. In its most severe form, it can lead to out-of-hospital cardiac arrest (OHCA). Despite medical advancements, survival rates in OHCA patients r…
View article: Coronary microvascular dysfunction in Takotsubo syndrome: an analysis using angiography-derived index of microcirculatory resistance
Coronary microvascular dysfunction in Takotsubo syndrome: an analysis using angiography-derived index of microcirculatory resistance Open
Background Coronary microvascular dysfunction (CMD) has been proposed as a crucial factor in the pathophysiology of Takotsubo syndrome (TTS). The angiography-derived index of microcirculatory resistance (caIMR) offers an alternative to con…
View article: Long-term functional cardiac changes in takotsubo syndrome
Long-term functional cardiac changes in takotsubo syndrome Open
Background Takotsubo syndrome has long been thought to be a benign condition once the acute event has been overcome. However, an increasing number of studies suggest that there might be long-term consequences. The aim of the present study …
View article: Coronary microvascular dysfunction in takotsubo syndrome: an analysis using angiography-derived index of microcirculatory resistance
Coronary microvascular dysfunction in takotsubo syndrome: an analysis using angiography-derived index of microcirculatory resistance Open
Background Coronary microvascular dysfunction (CMD) has been proposed to be a major contributing factor in the pathophysiology of Takotsubo syndrome (TTS). To asses CMD, the angiography-derived index of microcirculatory resistance (caIMR) …
View article: Obstructive Hypertrophic Cardiomyopathy and Takotsubo Syndrome: How to Deal With Left Ventricular Ballooning?
Obstructive Hypertrophic Cardiomyopathy and Takotsubo Syndrome: How to Deal With Left Ventricular Ballooning? Open
Currently, there are 2 proposed causes of acute left ventricular ballooning. The first is the most cited hypothesis that ballooning is caused by direct catecholamine toxicity on cardiomyocytes or by microvascular ischemia. We refer to this…
View article: Twenty-five-year trends in incidence, angiographic appearance, and management of spontaneous coronary artery dissection
Twenty-five-year trends in incidence, angiographic appearance, and management of spontaneous coronary artery dissection Open
SCAD represents an important entity of ACS that still might be underappreciated. The increasing incidence of SCAD is likely based on better awareness and familiarity with the disease. A lower need for intensive care treatment suggests posi…
View article: Takotsubo Syndrome and Spontaneous Coronary Artery Dissection
Takotsubo Syndrome and Spontaneous Coronary Artery Dissection Open
Acute coronary syndrome (ACS) in women presents unique challenges in terms of pathophysiology, diagnosis and management.Rare forms of ACS, such as takotsubo syndrome (TTS) and spontaneous coronary artery dissection (SCAD), have gained incr…
View article: Three-dimensional echocardiographic evaluation of longitudinal and non-longitudinal components of right ventricular contraction: results from the World Alliance of Societies of Echocardiography study
Three-dimensional echocardiographic evaluation of longitudinal and non-longitudinal components of right ventricular contraction: results from the World Alliance of Societies of Echocardiography study Open
Aims Right ventricular (RV) functional assessment is mainly limited to its longitudinal contraction. Dedicated three-dimensional echocardiography (3DE) software enabled the separate assessment of the non-longitudinal components of RV eject…
View article: Machine learning‐based prediction of in‐hospital death for patients with takotsubo syndrome: The <scp>InterTAK‐ML</scp> model
Machine learning‐based prediction of in‐hospital death for patients with takotsubo syndrome: The <span>InterTAK‐ML</span> model Open
Aims Takotsubo syndrome (TTS) is associated with a substantial rate of adverse events. We sought to design a machine learning (ML)‐based model to predict the risk of in‐hospital death and to perform a clustering of TTS patients to identify…
View article: Assessment of Artificial Intelligence in Echocardiography Diagnostics in Differentiating Takotsubo Syndrome From Myocardial Infarction
Assessment of Artificial Intelligence in Echocardiography Diagnostics in Differentiating Takotsubo Syndrome From Myocardial Infarction Open
In this cohort study, a real-time system for fully automated interpretation of echocardiogram videos was established and trained to differentiate TTS from AMI. While this system was more accurate than cardiologists in echocardiography-base…
View article: Impact of Atrial Fibrillation on Outcome in Takotsubo Syndrome: Data From the International Takotsubo Registry
Impact of Atrial Fibrillation on Outcome in Takotsubo Syndrome: Data From the International Takotsubo Registry Open
Background Atrial fibrillation (AF) is a major risk factor for mortality. The prevalence, clinical correlates, and prognostic impact of AF in Takotsubo syndrome (TTS) have not yet been investigated in a large patient cohort. This study aim…
View article: Dynamic Left Intraventricular Obstruction Phenotype in Takotsubo Syndrome
Dynamic Left Intraventricular Obstruction Phenotype in Takotsubo Syndrome Open
Takotsubo syndrome (TTS) is characterized by acute, generally transient left ventricular (LV) dysfunction. Although TTS has been long regarded as a benign condition, recent evidence showed that rate of acute complications and in-hospital m…
View article: Clinical conditions and echocardiographic parameters associated with mortality in COVID‐19
Clinical conditions and echocardiographic parameters associated with mortality in COVID‐19 Open
Background Coronavirus disease 2019 (COVID‐19) is a recently recognized viral infective disease which can be complicated by acute respiratory stress syndrome (ARDS) and cardiovascular complications including severe arrhythmias, acute coron…