Davide Gatti
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View article: Vitamin D Supplementation and Testosterone Levels in Breast Cancer Survivors
Vitamin D Supplementation and Testosterone Levels in Breast Cancer Survivors Open
Vitamin D plays a key role in immune modulation, cell proliferation, and hormone regulation. Dysregulated testosterone may contribute to breast cancer progression. We investigated whether long-term vitamin D supplementation affects serum t…
View article: ROMosozumab early experience in female patients with severe osteoporosis in an Italian real-world setting, the ROMEO study
ROMosozumab early experience in female patients with severe osteoporosis in an Italian real-world setting, the ROMEO study Open
The rapid increase in BMD with romosozumab supports its use for reducing fracture risk in postmenopausal women with severe osteoporosis, regardless of prior bisphosphonate exposure.
View article: Romosozumab in postmenopausal women with smoldering multiple myeloma: a prospective 12-mo study
Romosozumab in postmenopausal women with smoldering multiple myeloma: a prospective 12-mo study Open
Bone damage occurs early in the progression of plasma cell disorders. Romosozumab (ROMO), a sclerostin inhibitor with both anabolic and antiresorptive effects, may provide therapeutic benefit for this fracture-prone population. We conducte…
View article: Increase in serum DKK1 levels attenuates the anabolic response to romosozumab in postmenopausal osteoporosis
Increase in serum DKK1 levels attenuates the anabolic response to romosozumab in postmenopausal osteoporosis Open
Romosozumab is a monoclonal antibody against sclerostin that initially exhibits potent anabolic effects in treating osteoporosis. However, its efficacy diminishes after 6 mo, with bone formation markers declining despite continued therapy.…
View article: Longitudinal comparison of calprotectin and CRP in Rheumatoid arthritis: real-world evidence across three targeted therapies
Longitudinal comparison of calprotectin and CRP in Rheumatoid arthritis: real-world evidence across three targeted therapies Open
View article: Prevalence and determinants of vertebral fractures in a SLE cohort
Prevalence and determinants of vertebral fractures in a SLE cohort Open
Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterised by multiorgan involvement. Osteoporosis and fragility fractures, particularly vertebral fractures, are significant, yet often underestimated, comor…
View article: POS1195 OSTEOPOROSIS AND FRACTURES IN SYSTEMIC VASCULITIDES: A SYSTEMATIC REVIEW AND META-ANALYSIS
POS1195 OSTEOPOROSIS AND FRACTURES IN SYSTEMIC VASCULITIDES: A SYSTEMATIC REVIEW AND META-ANALYSIS Open
View article: POS0397 INCREASE IN SERUM DKK1 LEVELS ATTENUATES THE ANABOLIC RESPONSE TO ROMOSOZUMAB IN POSTMENOPAUSAL OSTEOPOROSIS
POS0397 INCREASE IN SERUM DKK1 LEVELS ATTENUATES THE ANABOLIC RESPONSE TO ROMOSOZUMAB IN POSTMENOPAUSAL OSTEOPOROSIS Open
View article: POS0626 RADIOFREQUENCY ECHOGRAPHIC MULTISPECTROMETRY (REMS): A NONINVASIVE TECHNOLOGY FOR MUSCLE ASSESSMENT IN SYSTEMIC SCLEROSIS
POS0626 RADIOFREQUENCY ECHOGRAPHIC MULTISPECTROMETRY (REMS): A NONINVASIVE TECHNOLOGY FOR MUSCLE ASSESSMENT IN SYSTEMIC SCLEROSIS Open
View article: ABS0350 LONG-TERM CHANGES IN PARAMETERS OF BONE QUALITY IN KIDNEY TRANSPLANT RECIPIENTS TREATED WITH DENOSUMAB
ABS0350 LONG-TERM CHANGES IN PARAMETERS OF BONE QUALITY IN KIDNEY TRANSPLANT RECIPIENTS TREATED WITH DENOSUMAB Open
View article: POS1220 VERTEBRAL FRACTURES AS A PREDICTOR OF REDUCED FORCED VITAL CAPACITY IN SUBJECTS WITH INTERSTITIAL LUNG DISEASE
POS1220 VERTEBRAL FRACTURES AS A PREDICTOR OF REDUCED FORCED VITAL CAPACITY IN SUBJECTS WITH INTERSTITIAL LUNG DISEASE Open
View article: ABS0307 GLUCOCORTICOID SPARING EFFECT OF JANUS KINASE INHIBITORS COMPARED TO BIOLOGICAL DISEASE MODIFYING ANTI-RHEUMATIC DRUGS IN RHEUMATOID ARTHRITIS
ABS0307 GLUCOCORTICOID SPARING EFFECT OF JANUS KINASE INHIBITORS COMPARED TO BIOLOGICAL DISEASE MODIFYING ANTI-RHEUMATIC DRUGS IN RHEUMATOID ARTHRITIS Open
View article: ABS0505 MEPOLIZUMAB 100 MG IN SEVERE ASTHMATIC PATIENTS WITH EGPA, LONG-TERM REAL-LIFE DATA
ABS0505 MEPOLIZUMAB 100 MG IN SEVERE ASTHMATIC PATIENTS WITH EGPA, LONG-TERM REAL-LIFE DATA Open
View article: Bone Metabolism and Inflammation Drive Structural Damage in Rheumatoid Arthritis: Clustering and Multivariable Analysis
Bone Metabolism and Inflammation Drive Structural Damage in Rheumatoid Arthritis: Clustering and Multivariable Analysis Open
Background Rheumatoid arthritis (RA) is characterized by synovial inflammation leading to joint damage, periarticular bone loss, and systemic osteoporosis. While inflammation is a primary driver of structural damage, dysregulation of the W…
View article: Osteoporosis and fractures in systemic vasculitides: a systematic review and meta-analysis
Osteoporosis and fractures in systemic vasculitides: a systematic review and meta-analysis Open
Background/aim We performed a systematic review and meta-analysis of observational studies aimed at investigating the prevalence of osteoporosis and osteoporotic fractures in subjects affected by systemic vasculitides (SVs) as well as to e…
View article: Bone mineral density is associated with pre-treatment pain levels of complex regional pain syndrome type 1 and predicts the response to N-containing bisphosphonates
Bone mineral density is associated with pre-treatment pain levels of complex regional pain syndrome type 1 and predicts the response to N-containing bisphosphonates Open
Lower BMD was associated with greater CRPS severity and better response to treatment. These findings support the roleof bone in CRPS pathogenesis and suggest that DXA-derived Z-scores may help identify patients most likely to benefit from …
View article: Long-Term Changes in Parameters of Bone Quality in Kidney Transplant Recipients Treated with Denosumab
Long-Term Changes in Parameters of Bone Quality in Kidney Transplant Recipients Treated with Denosumab Open
Kidney transplant recipients (KTRs) have an elevated fracture risk. While dual-energy X-ray absorptiometry (DXA) is commonly used to assess areal bone mineral density (aBMD), it does not capture all aspects of bone quality. We investigated…
View article: Diffuse idiopathic skeletal hyperostosis is associated with greater complexity of coronary artery disease burden on coronary angiography
Diffuse idiopathic skeletal hyperostosis is associated with greater complexity of coronary artery disease burden on coronary angiography Open
Objective. Diffuse idiopathic skeletal hyperostosis (DISH) is a common disorder characterized by ossification of tendons and ligaments. DISH has been largely associated with an increased risk of metabolic syndrome and type 2 diabetes. The …
View article: Radiofrequency Echographic Multi Spectrometry (REMS) Technology for Bone Health Status Evaluation in Kidney Transplant Recipients
Radiofrequency Echographic Multi Spectrometry (REMS) Technology for Bone Health Status Evaluation in Kidney Transplant Recipients Open
Background: A significant loss in bone density and strength occurs during the post-renal-transplant period with higher susceptibility to fracture. The study aims to compare the performance of the Radiofrequency Echographic Multi Spectromet…
View article: Effects of tofacitinib on bone turnover markers and bone modulators in patients with rheumatoid arthritis
Effects of tofacitinib on bone turnover markers and bone modulators in patients with rheumatoid arthritis Open
Treatment with tofacitinib was associated with a significant increase in sclerostin serum levels and a parallel decrease in markers of bone formation. However, no significant bone loss was observed.
View article: The role of 18FDG–PET imaging in VEXAS syndrome: a multicentric case series and a systematic review of the literature
The role of 18FDG–PET imaging in VEXAS syndrome: a multicentric case series and a systematic review of the literature Open
VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, and somatic) syndrome is characterized by heterogeneous clinical manifestations. Due to the inflammatory nature of this condition, 18-FDG–PET (18-fluorodeoxyglucose–positron emission …
View article: Glucocorticoid sparing effect of Janus kinase inhibitors compared to biologic disease modifying anti-rheumatic drugs in rheumatoid arthritis, a single-centre retrospective analysis
Glucocorticoid sparing effect of Janus kinase inhibitors compared to biologic disease modifying anti-rheumatic drugs in rheumatoid arthritis, a single-centre retrospective analysis Open
Background Glucocorticoid sparing in rheumatoid arthritis (RA) treatment is crucial to minimizing adverse effects associated with long-term use. Janus kinase inhibitors (JAKi) could potentially offer a more potent glucocorticoid-sparing ef…
View article: Expert opinion on the management of patients with osteoporosis with anabolic drugs in Italy
Expert opinion on the management of patients with osteoporosis with anabolic drugs in Italy Open
Objective. Fragility fractures (FF) resulting from osteoporosis pose a significant public health challenge in Italy, with considerable socio-health and economic implications. Despite the availability of safe and effective drugs, osteoporos…
View article: Progress in Flow Control and Drag Reduction
Progress in Flow Control and Drag Reduction Open
View article: Long-Term Bone Mineral Density Changes in Kidney Transplant Recipients Treated with Denosumab: A Retrospective Study with Nonequivalent Control Group
Long-Term Bone Mineral Density Changes in Kidney Transplant Recipients Treated with Denosumab: A Retrospective Study with Nonequivalent Control Group Open
Data on the effectiveness of denosumab on osteoporosis after kidney transplantation are limited. We investigated the long-term bone mineral density (BMD) changes in kidney transplant recipients (KTRs) treated with denosumab compared to unt…
View article: Effects of tofacitinib on bone turnover markers and bone modulators in patients with rheumatoid arthritis
Effects of tofacitinib on bone turnover markers and bone modulators in patients with rheumatoid arthritis Open
Background Rheumatoid arthritis (RA) is characterized by bone loss. It is unclear whether JAK inhibitors can attenuate bone loss in RA by modulating bone metabolism. The main objective of our study is to investigate the effects of tofaciti…
View article: New point-of-care calcaneal ultrasound densitometer (Osteosys BeeTLE) compared to standard dual-energy X-ray absorptiometry (DXA)
New point-of-care calcaneal ultrasound densitometer (Osteosys BeeTLE) compared to standard dual-energy X-ray absorptiometry (DXA) Open
View article: Post-diagnosis serum 25-hydroxyvitamin D concentrations in women treated for breast cancer participating in a lifestyle trial in Italy
Post-diagnosis serum 25-hydroxyvitamin D concentrations in women treated for breast cancer participating in a lifestyle trial in Italy Open
Objective. To report cross-sectionally serum levels of 25-hydroxyvitamin D [25(OH)D] in women living in Italy within 12 months from breast cancer (BC) diagnosis. Methods. Baseline data were obtained from 394 women diagnosed with primary BC…
View article: Romosozumab added to ongoing denosumab in postmenopausal osteoporosis, a prospective observational study
Romosozumab added to ongoing denosumab in postmenopausal osteoporosis, a prospective observational study Open
Background Optimization of sequential and combination treatment is crucial in shaping long-term management of postmenopausal osteoporosis (OP). Methods We conducted a 6-month prospective observational study on postmenopausal women with sev…
View article: Clinical Images: Erosive tophaceous gout and uric acid nephrolithiasis: microscopic and three‐dimensional high‐resolution peripheral quantitative computed tomography findings
Clinical Images: Erosive tophaceous gout and uric acid nephrolithiasis: microscopic and three‐dimensional high‐resolution peripheral quantitative computed tomography findings Open
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