This report highlights the importance of synergic surveillance, including virological, entomological and public health measures to control the spread of arboviral infections.

Avian influenza (AI), caused by Alphainfluenzavirus (family Orthomyxoviridae), poses significant threats to poultry, biodiversity, and public health. AI outbreaks in poultry lead to severe economic losses, while highly pathogenic strains (HPAIVs) severely impact wild bird populations, with implications for biodiversity and potential zoonotic risks. Similarly, arboviruses such as West Nile virus (WNV) and Usutu virus (USUV) are emerging zoonoses. WNV can cause severe neurological diseases in birds, humans, and othe…

The European subtype of tick-borne encephalitis virus (TBEV-Eur; species Orthoflavivirus encephalitidis, family Flaviviridae) was the only tick-borne flavivirus present in central Europe known to cause neurologic disease in humans and several animal species. Here, we report a tick-borne flavivirus isolated from Alpine chamois (Rupicapra rupicapra rupicapra) with encephalitis and attached ticks, present over a wide area in the Alps. Cases were detected in 2017 in Salzburg, Austria, and 2023 in Lombardy and Piedmont…

In May 2022, an expedition was conducted in the Gobi Desert, Mongolia, to investigate the viral diversity of bats, recognized as reservoirs of emerging zoonotic viruses. Bats were captured in six oases using mist nets and were identified morphologically and molecularly. Fecal samples were collected and screened using molecular protocol targeting viral agents of relevance to human and animal health, including coronaviruses, orthoreoviruses, herpesviruses, adenoviruses, flaviviruses, phleboviruses, paramyxoviruses, …

The Angiotensin Converting Enzyme 2 (ACE2) is the obligate receptor for the entry of SARS-CoV-2 into host cells, through high affinity interaction with the viral protein Spike. In this work, ACE2 is exploited to devise a supramolecular construct, able to deliver photoactive molecules to the viral surface. Using a modular approach, we propose a self-assembled photoactive supramolecular structure, where a biotinylated recombinant soluble human ACE2 (rshACE2) acts as a molecular decoy, to detract the viral particles …