Davide Stolfo
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View article: Adherence to guideline‐directed medical treatments in heart failure. A scientific statement of the Heart Failure Association ( <scp>HFA</scp> ) of the <scp>ESC</scp> and the <scp>ESC</scp> Working Group on Cardiovascular Pharmacotherapy
Adherence to guideline‐directed medical treatments in heart failure. A scientific statement of the Heart Failure Association ( <span>HFA</span> ) of the <span>ESC</span> and the <span>ESC</span> Working Group on Cardiovascular Pharmacotherapy Open
Heart failure (HF) affects over 60 million individuals globally. Contemporary guideline‐directed medical therapies (GDMT) reduce cardiovascular mortality and HF hospitalizations. However, medication non‐adherence represents a critical barr…
View article: Erratum in “Sharing diagnostic and therapeutic pathways in pulmonary arterial hypertension: a Roadmap for the Triveneto region”
Erratum in “Sharing diagnostic and therapeutic pathways in pulmonary arterial hypertension: a Roadmap for the Triveneto region” Open
View article: Fulminant Myocarditis Presenting With Refractory Ventricular Fibrillation During BRAF/MEK Inhibitor Therapy
Fulminant Myocarditis Presenting With Refractory Ventricular Fibrillation During BRAF/MEK Inhibitor Therapy Open
View article: Genetic and Phenotypic Characterization of Nexilin (NEXN)–Related Cardiomyopathy
Genetic and Phenotypic Characterization of Nexilin (NEXN)–Related Cardiomyopathy Open
View article: The crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the <scp>ESC</scp>
The crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the <span>ESC</span> Open
A better understanding of additional mechanisms of heart failure (HF) progression may allow a different and more complete phenotyping of the disease and identification of novel therapeutic targets. Persistent latent myocardial inflammation…
View article: Sharing Diagnostic and Therapeutic Pathways in Pulmonary Arterial Hypertension: A Roadmap for the Triveneto Region
Sharing Diagnostic and Therapeutic Pathways in Pulmonary Arterial Hypertension: A Roadmap for the Triveneto Region Open
Background: Pulmonary arterial hypertension (PAH) is a rare and progressive disease characterized by high mortality and a significant impact on quality of life. Despite therapeutic advances, considerable heterogeneity persists in Italy’s d…
View article: The Diagnostic and Prognostic Value of the 12-Lead ECG in Arrhythmogenic Left Ventricular Cardiomyopathy
The Diagnostic and Prognostic Value of the 12-Lead ECG in Arrhythmogenic Left Ventricular Cardiomyopathy Open
View article: Aetiological phenotypes of atrial and ventricular secondary tricuspid regurgitation and their prognostic implications: insights from the <scp>CARE</scp>‐<scp>TR</scp> registry
Aetiological phenotypes of atrial and ventricular secondary tricuspid regurgitation and their prognostic implications: insights from the <span>CARE</span>‐<span>TR</span> registry Open
Aims To report prevalence and clinical outcomes of different aetiological phenotypes of atrial and ventricular secondary tricuspid regurgitation (ASTR/VSTR). Methods and results The Consecutive pAtients with seveRE Tricuspid Regurgitation …
View article: PARENTERAL PROSTANOIDS IN OLDER PAH PATIENTS
PARENTERAL PROSTANOIDS IN OLDER PAH PATIENTS Open
Background The use and effectiveness of parenteral prostanoids in older patients with pulmonary arterial hypertension (PAH) are unknown. We investigated the association of paretenteral prostanoids use with mortality in elderly PAH patients…
View article: Integrated role of cardiac magnetic resonance and genetics in predicting left ventricular reverse remodelling in dilated and non‐dilated cardiomyopathy
Integrated role of cardiac magnetic resonance and genetics in predicting left ventricular reverse remodelling in dilated and non‐dilated cardiomyopathy Open
Aims Left ventricular reverse remodelling (LVRR) is a prognostic marker in patients with dilated (DCM) and non‐dilated left ventricular cardiomyopathy (NDLVC). The utility of combining late gadolinium enhancement (LGE) and genetic testing …
View article: Prediction and prognostic role of left ventricular systolic dysfunction in family screening for dilated cardiomyopathy and non‐dilated left ventricular cardiomyopathy
Prediction and prognostic role of left ventricular systolic dysfunction in family screening for dilated cardiomyopathy and non‐dilated left ventricular cardiomyopathy Open
Aims The prognostic significance of detecting left ventricular (LV) systolic dysfunction during family screening programmes (FSPs) in relatives of probands affected by dilated (DCM) and non‐dilated left ventricular (NDLVC) cardiomyopathies…
View article: How to handle polypharmacy in heart failure. A clinical consensus statement of the Heart Failure Association of the <scp>ESC</scp>
How to handle polypharmacy in heart failure. A clinical consensus statement of the Heart Failure Association of the <span>ESC</span> Open
The multiplicity of coexisting comorbidities affecting patients with heart failure ( HF) , together with the availability of multiple treatments improving prognosis in HF with reduced ejection fraction, has led to an increase in the number…
View article: Machine-learning phenotyping of patients with functional mitral regurgitation undergoing transcatheter edge-to-edge repair: the MITRA-AI study
Machine-learning phenotyping of patients with functional mitral regurgitation undergoing transcatheter edge-to-edge repair: the MITRA-AI study Open
Aims Severe functional mitral regurgitation (FMR) may benefit from mitral transcatheter edge-to-edge repair (TEER), but selection of patients remains to be optimized. Objectives The aim of this study was to use machine-learning (ML) approa…
View article: Heart failure and tricuspid regurgitation: let the outcome lead
Heart failure and tricuspid regurgitation: let the outcome lead Open
View article: Predicting survival in patients with severe heart failure: Risk score validation in the <scp>HELP</scp>‐<scp>HF</scp> cohort
Predicting survival in patients with severe heart failure: Risk score validation in the <span>HELP</span>‐<span>HF</span> cohort Open
Aims Accurate selection of patients with severe heart failure (HF) who might benefit from advanced therapies is crucial. The present study investigates the performance of the available risk scores aimed at predicting the risk of mortality …
View article: Intervention, improved prevention, imaging, inflammation, and innovation: the five I's cardiovascular highlights in <i>EHJ Open</i> 2024
Intervention, improved prevention, imaging, inflammation, and innovation: the five I's cardiovascular highlights in <i>EHJ Open</i> 2024 Open
peer reviewed
View article: Pathophysiology of dilated cardiomyopathy: from mechanisms to precision medicine
Pathophysiology of dilated cardiomyopathy: from mechanisms to precision medicine Open
View article: Status and timing of angiotensin receptor–neprilysin inhibitor implementation in patients with heart failure and reduced ejection fraction: Data from the Swedish Heart Failure Registry
Status and timing of angiotensin receptor–neprilysin inhibitor implementation in patients with heart failure and reduced ejection fraction: Data from the Swedish Heart Failure Registry Open
Aims We explored timing, settings and predictors of angiotensin receptor–neprilysin inhibitor (ARNI) initiation in a large, nationwide cohort of patients with heart failure (HF) with reduced ejection fraction (HFrEF). Methods and results P…
View article: Does extracorporeal cardiopulmonary resuscitation improve survival with favorable neurological outcome in out-of-hospital cardiac arrest? A systematic review and meta-analysis
Does extracorporeal cardiopulmonary resuscitation improve survival with favorable neurological outcome in out-of-hospital cardiac arrest? A systematic review and meta-analysis Open
View article: Phenotype and outcomes according to loop diuretic use in pulmonary arterial hypertension
Phenotype and outcomes according to loop diuretic use in pulmonary arterial hypertension Open
Aims The use of loop diuretics in pulmonary arterial hypertension (PAH) is less frequent compared with heart failure. The clinical and prognostic characteristics of PAH patients according to loop diuretic use remain unexplored. In this stu…
View article: Impact of malnutrition in patients with severe heart failure
Impact of malnutrition in patients with severe heart failure Open
Aim The role of malnutrition among patients with severe heart failure (HF) is not well established. We evaluated the incidence, predictors, and prognostic impact of malnutrition in patients with severe HF. Methods and results Nutritional s…
View article: Differences in presentation, diagnosis and management of heart failure in women. A scientific statement of the Heart Failure Association of the ESC
Differences in presentation, diagnosis and management of heart failure in women. A scientific statement of the Heart Failure Association of the ESC Open
Despite the progress in the care of individuals with heart failure (HF), important sex disparities in knowledge and management remain, covering all the aspects of the syndrome, from aetiology and pathophysiology to treatment. Important dis…
View article: How to tackle therapeutic inertia in heart failure with reduced ejection fraction. A scientific statement of the Heart Failure Association of the ESC
How to tackle therapeutic inertia in heart failure with reduced ejection fraction. A scientific statement of the Heart Failure Association of the ESC Open
Guideline‐directed medical therapy (GDMT) in patients with heart failure and reduced ejection fraction (HFrEF) reduces morbidity and mortality, but its implementation is often poor in daily clinical practice. Barriers to implementation inc…
View article: Impact of DCM-Causing Genetic Background on Long-Term Response to Cardiac Resynchronization Therapy
Impact of DCM-Causing Genetic Background on Long-Term Response to Cardiac Resynchronization Therapy Open
Genotyping contributes to the risk stratification of patients with DCM undergoing CRT implantation in terms of LV remodeling and outcomes.
View article: Frailty according to the 2019 HFA‐ESC definition in patients at risk for advanced heart failure: Insights from the HELP‐HF registry
Frailty according to the 2019 HFA‐ESC definition in patients at risk for advanced heart failure: Insights from the HELP‐HF registry Open
Aims Frailty is highly prevalent in patients with heart failure (HF), but a concordant definition of this condition is lacking. The Heart Failure Association of the European Society of Cardiology (HFA‐ESC) proposed in 2019 a new multi‐doma…
View article: Sex differences in the prognostic role of achieving target doses of heart failure medications: Data from the Swedish Heart Failure Registry
Sex differences in the prognostic role of achieving target doses of heart failure medications: Data from the Swedish Heart Failure Registry Open
Aims Guidelines recommend target doses (TD) of heart failure (HF) with reduced ejection fraction (HFrEF) medications regardless of sex. Differences in pharmacokinetics and pharmacodynamics may explain heterogeneity in treatment response, a…
View article: Magnetic Resonance Imaging Characterization and Clinical Outcomes of Dilated and Arrhythmogenic Left Ventricular Cardiomyopathies
Magnetic Resonance Imaging Characterization and Clinical Outcomes of Dilated and Arrhythmogenic Left Ventricular Cardiomyopathies Open
View article: Glucagon-like peptide-1 receptor agonists use and associations with outcomes in heart failure and type 2 diabetes: data from the Swedish Heart Failure and Swedish National Diabetes Registries
Glucagon-like peptide-1 receptor agonists use and associations with outcomes in heart failure and type 2 diabetes: data from the Swedish Heart Failure and Swedish National Diabetes Registries Open
Aims To assess the use and associations with outcomes of glucagon-like peptide-1 receptor agonists (GLP-1 RA) in a real-world population with heart failure (HF) and type 2 diabetes mellitus (T2DM). Methods and results The Swedish HF Regist…
View article: Frequency, characteristics and risk assessment of pulmonary arterial hypertension with a left heart disease phenotype
Frequency, characteristics and risk assessment of pulmonary arterial hypertension with a left heart disease phenotype Open
Aim To obtain real-world evidence about the features and risk stratification of pulmonary arterial hypertension (PAH) with a left heart disease (LHD) phenotype (PAH-LHD). Methods and results By reviewing the records of consecutive incident…
View article: Impact of coronary microvascular dysfunction in heart failure with preserved ejection fraction: a meta‐analysis
Impact of coronary microvascular dysfunction in heart failure with preserved ejection fraction: a meta‐analysis Open
Aims Several mechanisms have been identified in the aetiopathogenesis of heart failure with preserved ejection fraction (HFpEF). Among these, coronary microvascular dysfunction (CMD) may play a key pathophysiological role. We performed a s…