Dawei Yue
YOU?
Author Swipe
View article: Hepatic and intestinal tissue-specific <i>Fxr</i> deficiency alters bile acid homeostasis in female mice
Hepatic and intestinal tissue-specific <i>Fxr</i> deficiency alters bile acid homeostasis in female mice Open
We successfully developed a double tissue-specific Fxr knockout (DKO) mouse model, which provides a novel tool for investigation of FXR functions in the liver and intestine. Unlike whole body KO, the DKO model excludes the FXR impact on ot…
View article: Biological functions and pharmacological behaviors of bile acids in metabolic diseases
Biological functions and pharmacological behaviors of bile acids in metabolic diseases Open
Bile acids circulate primarily within the enterohepatic circulation, where they help maintain a healthy digestive system. Disruptions in their balance are linked to metabolic disorders, hepatobiliary diseases and intestinal inflammation. T…