Dawit Hailu Alemayehu
YOU?
Author Swipe
View article: Molecular characterization and genotyping of Newcastle disease viruses using whole-genome sequencing from poultry farms in parts of Amhara Regions, and central Ethiopia
Molecular characterization and genotyping of Newcastle disease viruses using whole-genome sequencing from poultry farms in parts of Amhara Regions, and central Ethiopia Open
View article: Whole genome sequencing analysis of antibiotic resistant genes of Shigella species: A systematic review and meta-analysis
Whole genome sequencing analysis of antibiotic resistant genes of Shigella species: A systematic review and meta-analysis Open
Background In developing nations, Shigella species are the leading cause of epidemic dysentery, especially among children under five. Antibiotic resistance has spread quickly among Shigella species as a result of inappropriate antibiotic u…
View article: Therapeutic Efficacy of Artemether-Lumefantrine (AL) plus Single Low Dose Primaquine for the treatment of uncomplicated <i>falciparum</i> malaria in a high transmission setting, Western Ethiopia
Therapeutic Efficacy of Artemether-Lumefantrine (AL) plus Single Low Dose Primaquine for the treatment of uncomplicated <i>falciparum</i> malaria in a high transmission setting, Western Ethiopia Open
Background The development and spread of drug-resistant parasites continue to threaten the move toward malaria elimination. Therapeutic efficacy and resistant marker studies are needed to guide national control programs. In African setting…
View article: Molecular Characterization and Genotyping of Newcastle Disease Viruses Using Whole- Genome Sequencing from Poultry Farms in Parts of Amhara Regions, and Central Ethiopia
Molecular Characterization and Genotyping of Newcastle Disease Viruses Using Whole- Genome Sequencing from Poultry Farms in Parts of Amhara Regions, and Central Ethiopia Open
Background Newcastle disease (ND) is a major viral infection of poultry caused by virulent strains of avian paramyxovirus type 1, resulting in considerable global economic losses. In Ethiopia, ND outbreaks persist despite vaccination effor…
View article: Draft genome sequences of four Newcastle disease virus isolates from commercial poultry farms in Ethiopia
Draft genome sequences of four Newcastle disease virus isolates from commercial poultry farms in Ethiopia Open
Genome sequencing of four Newcastle disease virus (NDV) isolates from vaccinated chickens in Central Ethiopia, North Wollo, and Shewa (April 2023–June 2024) revealed highly virulent strains, belonging to newly identified subgroups within g…
View article: Phenotypic and genotypic relationships between Shigella species and Escherichia coli O37:H10 isolates in Addis Ababa, Ethiopia
Phenotypic and genotypic relationships between Shigella species and Escherichia coli O37:H10 isolates in Addis Ababa, Ethiopia Open
Using whole genome sequencing (WGS), all 28 S. sonnei identified with antisera were also verified as S. sonnei, while all nine isolates of S. flexneri were found to be E. coli O37:H10. One S. flexneri sample, identified serologically, was …
View article: Genotypic drug resistance and transmission clusters of Mycobacterium tuberculosis isolates among Ethiopian returnees from Saudi Arabia
Genotypic drug resistance and transmission clusters of Mycobacterium tuberculosis isolates among Ethiopian returnees from Saudi Arabia Open
Background Human migration significantly contributes to the global spread of infectious diseases. In recent years, Ethiopia has experienced an increased influx of returnees from the Kingdom of Saudi Arabia. These migrants were often held i…
View article: Pretreatment HIV‐1 Drug Resistance Among Newly Diagnosed People in Eastern Ethiopia
Pretreatment HIV‐1 Drug Resistance Among Newly Diagnosed People in Eastern Ethiopia Open
Background and Aims In Ethiopia, HIV‐1 pretreatment drug resistance (PDR) data are limited owing to a lack of routine genotyping resistance tests. This study aimed to determine the prevalence of HIV‐1 PDR mutations and genetic diversity am…
View article: Resting habitat, blood meal source and viral infection rate of Aedes aegypti (Diptera: Culicidae) in the Southern Afar Region of Ethiopia
Resting habitat, blood meal source and viral infection rate of Aedes aegypti (Diptera: Culicidae) in the Southern Afar Region of Ethiopia Open
The majority of Ae. aegypti collections were made during the wet season from outdoor resting sites, particularly from tyres. Thus, outdoor targeted management of Ae. aegypti is recommended as a strategy particularly tyre removal during the…
View article: Persistence and clearance rates of human papillomaviruses in a cohort of women treated or not treated for cervical dysplasia in northwest Ethiopia
Persistence and clearance rates of human papillomaviruses in a cohort of women treated or not treated for cervical dysplasia in northwest Ethiopia Open
Persistence of high-risk Human papillomaviruses (HR-HPV) infection increases the risk of precancerous lesions development. The aim of this study was to assess the persistence and clearance rate of HPV infection. A prospective cohort study …
View article: Performance Comparison of Two In-House PCR Methods for Detecting Neisseria meningitidis in Asymptomatic Carriers and Antimicrobial Resistance Profiling
Performance Comparison of Two In-House PCR Methods for Detecting Neisseria meningitidis in Asymptomatic Carriers and Antimicrobial Resistance Profiling Open
Background/Objective: Bacteriological culture has been a widely used method for the detection of meningococcus, but it has low sensitivity and a long turnaround time. Molecular detection targeting capsule transport A (ctrA) gene has been u…
View article: Integrating genomic, transcriptomic, and phenotypic information to explore drug resistance in <i>Mycobacterium tuberculosis</i> sub-lineage 4.2.2.2
Integrating genomic, transcriptomic, and phenotypic information to explore drug resistance in <i>Mycobacterium tuberculosis</i> sub-lineage 4.2.2.2 Open
Aims Mycobacterium tuberculosis (Mtb) remains a major global health challenge, particularly due to increasing drug resistance. Beyond the well-characterized mutations, the mechanisms involved in driving resistance appear to be more complex…
View article: Lineage B Genotype III of Dengue Virus Serotype 3 (DENV-3III_B) Is Responsible for Dengue Outbreak in Dire Dawa City, Ethiopia, 2023
Lineage B Genotype III of Dengue Virus Serotype 3 (DENV-3III_B) Is Responsible for Dengue Outbreak in Dire Dawa City, Ethiopia, 2023 Open
The eastern parts of Ethiopia, including Dire Dawa City, have experienced annual dengue fever (DF) outbreaks since 2013, leading to significant healthcare and economic impacts. However, comprehensive evidence on the specific dengue virus (…
View article: Phenotypic drug resistance and genetic mutations linked to resistance among extrapulmonary tuberculosis patients in Ethiopia: Insights from Whole Genome Sequencing
Phenotypic drug resistance and genetic mutations linked to resistance among extrapulmonary tuberculosis patients in Ethiopia: Insights from Whole Genome Sequencing Open
View article: Genotypes and drug resistance pattern of Mycobacterium tuberculosis complex among clinically diagnosed pulmonary tuberculosis patients
Genotypes and drug resistance pattern of Mycobacterium tuberculosis complex among clinically diagnosed pulmonary tuberculosis patients Open
Background Clinically diagnosed pulmonary tuberculosis (TB) (CDPTB) patients account for a huge proportion of TB. However, little is known about the genetic diversity and drug resistance profile of Mycobacterium tuberculosis Complex (MTBC)…
View article: Whole genome sequencing and antimicrobial resistance among clinical isolates of Shigella sonnei in Addis Ababa, Ethiopia
Whole genome sequencing and antimicrobial resistance among clinical isolates of Shigella sonnei in Addis Ababa, Ethiopia Open
Background Shigellosis is an acute gastroenteritis infection and one of Ethiopia’s most common causes of morbidity and mortality, especially in children under five. Antimicrobial resistance (AMR) has spread quickly among Shigella species d…
View article: Genomic analysis and characterization of lytic bacteriophages that target antimicrobial resistant Escherichia coli in Addis Ababa, Ethiopia
Genomic analysis and characterization of lytic bacteriophages that target antimicrobial resistant Escherichia coli in Addis Ababa, Ethiopia Open
The emergence of antibiotic resistance in E. coli strains has sparked a fervent investigation of alternative therapies, such as the use of lytic bacteriophages. Phage genome sequence analysis is a novel method for learning more abou…
View article: A prospective, multicenter study of hepatitis B birth-dose vaccine with or without hepatitis B immunoglobulin in preventing mother-to-child transmission of hepatitis B virus in Ethiopia
A prospective, multicenter study of hepatitis B birth-dose vaccine with or without hepatitis B immunoglobulin in preventing mother-to-child transmission of hepatitis B virus in Ethiopia Open
Birth-dose HBV vaccine with or without HBIg significantly reduced the risk of MTCT of HBV in Ethiopia. Improved coverage of birth-dose HBV vaccine should be an urgent priority.
View article: Lineage B Genotype III of Dengue Virus Serotype 3 (DENV-3III_B) is responsible for Dengue Outbreak in Dire Dawa City, Ethiopia, 2023
Lineage B Genotype III of Dengue Virus Serotype 3 (DENV-3III_B) is responsible for Dengue Outbreak in Dire Dawa City, Ethiopia, 2023 Open
Background: The eastern parts of Ethiopia, including Dire Dawa City, have faced annual dengue fever (DF) outbreaks since 2013, resulting in substantial healthcare and economic consequences. However, there remains a lack of comprehensive ev…
View article: Predominance of Dengue Virus Serotype-1/Genotype-I in Eastern and Southeastern Ethiopia
Predominance of Dengue Virus Serotype-1/Genotype-I in Eastern and Southeastern Ethiopia Open
We determined the dengue virus (DENV) serotypes and genotypes in archived serum samples that were collected during the 2014–2016 and 2021 dengue outbreaks in Dire Dawa City and the Somali region in Ethiopia. DENV serotype 1 (DENV-1) was pr…
View article: Genetic diversity and distribution of noroviruses among all age groups of patients with diarrhea in Amhara National Regional State, Ethiopia
Genetic diversity and distribution of noroviruses among all age groups of patients with diarrhea in Amhara National Regional State, Ethiopia Open
Background Norovirus (NoV) is the leading cause of diarrheal disease worldwide and the impact is high in developing countries, including Ethiopia. Moreover, there is a significant and fluctuating global genetic diversity that varies across…
View article: Molecular Detection and Characterization of Newcastle Disease Virus from Chickens in Mid-Rift Valley and Central Part of Ethiopia
Molecular Detection and Characterization of Newcastle Disease Virus from Chickens in Mid-Rift Valley and Central Part of Ethiopia Open
The current study indicates the existence of different NDV strain genotype from that of the vaccine strain currently used. Even though large-scale characterization of several isolates is required at national level, the current study laid b…
View article: Molecular characterization of carbapenemase and extended spectrum beta-lactamase producing Acinetobacter baumannii isolates causing surgical site infections in Ethiopia
Molecular characterization of carbapenemase and extended spectrum beta-lactamase producing Acinetobacter baumannii isolates causing surgical site infections in Ethiopia Open
Background Acinetobacter baumannii is an opportunistic pathogen that can cause a variety of nosocomial infections in humans. This study aimed to molecularly characterize extended-spectrum beta-lactamase (ESBL) producing and carbapenem-resi…
View article: Characterization of human papillomavirus genotypes and their coverage in vaccine delivered to Ethiopian women
Characterization of human papillomavirus genotypes and their coverage in vaccine delivered to Ethiopian women Open
Cervical cancer is a significant public health concern in Ethiopia. It is mainly caused by persistent infection with the human papillomaviruses. The aim of this study was to assess the relationship between carcinogenic risk of probable, po…
View article: Persistence and clearance rate of human papillomaviruses with and without treatment for cervical dysplasia
Persistence and clearance rate of human papillomaviruses with and without treatment for cervical dysplasia Open
Infections of Human papillomaviruses (HPVs) frequently spread through sexual contact. The aim of this study was to assess the persistence and clearance rate of HPV infection. A prospective cohort study was conducted between January and Dec…
View article: Whole genome sequence analysis and characterization of lytic bacteriophages against antimicrobial-resistant diarrheagenic Escherichia coli strains isolated from various sources in Addis Ababa, Ethiopia
Whole genome sequence analysis and characterization of lytic bacteriophages against antimicrobial-resistant diarrheagenic Escherichia coli strains isolated from various sources in Addis Ababa, Ethiopia Open
The emergence of antibiotic resistance in E. coli strains has sparked a fervent investigation of alternative therapies such as the use of lytic bacteriophages. Phage whole genome sequencing is a novel method for learning more about protein…
View article: High rate of non-vaccine targeted high-risk HPV genotypes circulate among women in Eastern Ethiopia
High rate of non-vaccine targeted high-risk HPV genotypes circulate among women in Eastern Ethiopia Open
View article: High Efficacy of Artemether-Lumefantrine and Artesunate-Pyronaridine with Single Low Dose Primaquine in Adults with Plasmodium Falciparum with High Prevalence of Markers of Partial Artemisinin Resistance and Pfhrp2/3 Gene Deletions in Ethiopia: A Single-Blind Randomized Controlled Trial
High Efficacy of Artemether-Lumefantrine and Artesunate-Pyronaridine with Single Low Dose Primaquine in Adults with Plasmodium Falciparum with High Prevalence of Markers of Partial Artemisinin Resistance and Pfhrp2/3 Gene Deletions in Ethiopia: A Single-Blind Randomized Controlled Trial Open
View article: The expression of matrix metalloproteinase 2, 9 and 11 in Ethiopian breast cancer patients
The expression of matrix metalloproteinase 2, 9 and 11 in Ethiopian breast cancer patients Open
View article: Low level of HIV-1C integrase strand transfer inhibitor resistance mutations among recently diagnosed ART-naive Ethiopians
Low level of HIV-1C integrase strand transfer inhibitor resistance mutations among recently diagnosed ART-naive Ethiopians Open
With the widespread use of Integrase strand transfer inhibitors (INSTIs), surveillance of HIV-1 pretreatment drug resistance is critical in optimizing antiretroviral treatment efficacy. However, despite the introduction of these drugs, dat…