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View article: Prescribing Patterns and Off-Label Use of Gabapentinoid Agents at Dhulikhel Hospital, Nepal: A Cross-Sectional Study
Prescribing Patterns and Off-Label Use of Gabapentinoid Agents at Dhulikhel Hospital, Nepal: A Cross-Sectional Study Open
This study highlights the extensive off-label and sub-therapeutic use of gabapentinoids at Dhulikhel Hospital and reveals significant gaps in patient knowledge. This emphasizes the need for stricter prescribing guidelines, improved healthc…
View article: Supplementary Figure S1 from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells
Supplementary Figure S1 from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells Open
Analysis of phenotype, activation, maturation and checkpoint markers on E + E MART-1 Tet+ CD8+ T-cells.
View article: Supplementary Figure S7 from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells
Supplementary Figure S7 from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells Open
Functional analysis of nano-aAPC expanded MART-1 Tet+ CD8+ T-cells post-PD-1 treatment.
View article: Supplementary Figure S6 from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells
Supplementary Figure S6 from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells Open
Nano-aAPC expanded MART-1 Tet+ cells from patients pre- and post-PD-1 treatment.
View article: Supplementary Figure S1 from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells
Supplementary Figure S1 from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells Open
Analysis of phenotype, activation, maturation and checkpoint markers on E + E MART-1 Tet+ CD8+ T-cells.
View article: Supplementary Figure S3 from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells
Supplementary Figure S3 from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells Open
Polyfunctional analysis of MART-1 Tet+ CD8+ T-cells expanded by nano-aAPC or DCs.
View article: Data from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells
Data from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells Open
Purpose:Generation of antigen-specific T cells from patients with cancer employs large numbers of peripheral blood cells and/or tumor-infiltrating cells to generate antigen-presenting and effector cells commonly requiring multiple rounds o…
View article: Supplementary Figure S8 from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells
Supplementary Figure S8 from Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells Open
TCR repertoire analysis of MART-1 Tet+ CD8+ T-cells.
View article: 1466 Novel cell phenotypes correlated with checkpoint immunotherapy responses identified in the tumor and immune microenvironment of patients with metastatic melanoma
1466 Novel cell phenotypes correlated with checkpoint immunotherapy responses identified in the tumor and immune microenvironment of patients with metastatic melanoma Open
Background Visualizing and profiling cells within the tumor microenvironment (TME) is an important component of translational studies, particularly with the advent of immunotherapies. Successful optimization and utilization of multiplex im…
View article: 285 Multiomic analysis of TIL suggests that CD4+ polarization represses TIL expansion and CD8+ activation and is associated with progression of disease
285 Multiomic analysis of TIL suggests that CD4+ polarization represses TIL expansion and CD8+ activation and is associated with progression of disease Open
Background Tumor Infiltrating Lymphocyte (TIL) Adoptive Cell Transfer (ACT) is effective in treating malignant melanoma and other solid tumors. The success of TIL ACT relies on the adequate expansion of TIL, with previous studies showing a…
View article: Promoting the practice of clinical Pharmacy
Promoting the practice of clinical Pharmacy Open
View article: Immunosuppressives and enteral feeding tubes: An integrative review
Immunosuppressives and enteral feeding tubes: An integrative review Open
The lack of information about the administration of immunosuppressive drugs through enteral feeding tubes should not be a limiting factor, considering the need for treatment of patients in these circumstances. Risks and benefits must be ca…
View article: Características sociais e assistenciais dos encaminhamentos aos serviços de saúde mental infantojuvenil
Características sociais e assistenciais dos encaminhamentos aos serviços de saúde mental infantojuvenil Open
O objetivo do estudo foi comparar características sociais, demográficas e assistenciais de crianças e adolescentes atendidos nos serviços de saúde mental em uma Região Metropolitana do Nordeste do Brasil. Estudo transversal com crianças e …
View article: Assessment of Knowledge, Skills and Attitudes in the Use of Information Technology to Support Hospital Pharmacists Clinical Practice: Development and Validation of a Questionnaire
Assessment of Knowledge, Skills and Attitudes in the Use of Information Technology to Support Hospital Pharmacists Clinical Practice: Development and Validation of a Questionnaire Open
Background: This study aimed to describe the steps to construct and validate a questionnaire to identify the knowledge, skills and attitudes of hospital pharmacists in the use of information technology and electronic tools…
View article: Issue Information ‐ TOC
Issue Information ‐ TOC Open
View article: 106 Swine Modeling: An Integrated Approach to Providing Complete Nutritional Solutions.
106 Swine Modeling: An Integrated Approach to Providing Complete Nutritional Solutions. Open
Swine growth models, which predict the responses of pigs to nutrient inputs, have evolved considerably since Whittemore and Fawcett (1976) and Emmans (1981) published the first conceptual frameworks. A proposed integrated model that encomp…
View article: Knowledge, skills and attitudes of hospital pharmacists in the use of information technology and electronic tools to support clinical practice: A Brazilian survey
Knowledge, skills and attitudes of hospital pharmacists in the use of information technology and electronic tools to support clinical practice: A Brazilian survey Open
These results will assist in defining minimal competencies for the training of pharmacists in the field of information technology to support clinical practice. Knowledge and skill gaps are evident in the use of bibliographic databases, spr…
View article: A Comprehensive List of Items to be Included on a Pediatric Drug Monograph
A Comprehensive List of Items to be Included on a Pediatric Drug Monograph Open
OBJECTIVES Children require special considerations for drug prescribing. Drug information summarized in a formulary containing drug monographs is essential for safe and effective prescribing. Currently, little is known about the informatio…
View article: O papel dos farmacêuticos hospitalares na prevenção de reações adversas a medicamentos : THE ROLE OF HOSPITAL PHARMACISTS IN THE PREVENTION OF ADVERSE DRUG REACTIONS
O papel dos farmacêuticos hospitalares na prevenção de reações adversas a medicamentos : THE ROLE OF HOSPITAL PHARMACISTS IN THE PREVENTION OF ADVERSE DRUG REACTIONS Open
A significant proportion of these events are estimated to be preventable1so the question arisesas to whether health professionals, including pharmacists, are doing enough to prevent ADRs at the timeof prescribing or to identify their onset…
View article: Manipulação de líquidos orais para crianças: reconhecendo e minimizando os riscos
Manipulação de líquidos orais para crianças: reconhecendo e minimizando os riscos Open
“Compounding of medicines” (termo inglês utilizado que significa manipulação, transformação ou dispensação extemporânea de medicamentos para a individualização da dose), geralmente ocorre na farmácia hospitalar ou comunitária. As práticas …
View article: GAMMA RADIATION AS A METHOD FOR STERILIZATION OF ALL-IN-ONE ADMIXTURES BAGS FOR CLINICAL USE: A STUDY OF STABILITY
GAMMA RADIATION AS A METHOD FOR STERILIZATION OF ALL-IN-ONE ADMIXTURES BAGS FOR CLINICAL USE: A STUDY OF STABILITY Open
Objective: The aim of this work was to evaluate the stability of all-in-one (AIO) admixtures exposed to gamma irradiation sterilization. Methods: The samples were divided into four groups with 10 bags each: a) Group I: control samples …
View article: The effects of aging, malingering, and traumatic brain injury on computerized trail-making test performance
The effects of aging, malingering, and traumatic brain injury on computerized trail-making test performance Open
Data from the C-TMT trail making test