Daxing Tang
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View article: PPP1R12A mutation leads to different genders of twinning: a case report and literature review
PPP1R12A mutation leads to different genders of twinning: a case report and literature review Open
This is the first instance of identical twins with a heterozygous mutation (c.1551-2A>G) in the PPP1R12A gene, associated with UBMS and DSD. The same variation resulted in identical twins exhibiting different genital phenotypes and …
View article: Medium- and long-term outcomes of tunneled labial mucosa tube grafts for the repair of primary severe hypospadias and failed hypospadias
Medium- and long-term outcomes of tunneled labial mucosa tube grafts for the repair of primary severe hypospadias and failed hypospadias Open
Objective This study aimed to evaluate the medium and long-term outcomes of tunneled labial mucosa tube graft urethroplasty in the treatment of primary severe hypospadias and failed hypospadias. Methods We retrospectively reviewed the medi…
View article: Development and validation of a predictive model for testicular atrophy after orchiopexy in children with testicular torsion
Development and validation of a predictive model for testicular atrophy after orchiopexy in children with testicular torsion Open
View article: Diagnostic role of contrast-enhanced voiding urosonography (ceVUS) in pediatric duplex kidneys – a comparison with voiding cystourethrography (VCUG)
Diagnostic role of contrast-enhanced voiding urosonography (ceVUS) in pediatric duplex kidneys – a comparison with voiding cystourethrography (VCUG) Open
Aim: The present study aimed to assess the diagnostic efficacy of contrast-enhanced voiding urosonography (ceVUS) using SonoVue for evaluating duplex kidneys, and to compare it with fluoroscopic voiding cystourethrography (VCUG). Material …
View article: Role and significance of SIRT1 in regulating the LPS-activated pyroptosis pathway in children with congenital hydronephrosis
Role and significance of SIRT1 in regulating the LPS-activated pyroptosis pathway in children with congenital hydronephrosis Open
Objective To explore the characteristics and mechanism of sirtuin 1 (SIRT1) in lipopolysaccharide (LPS)-activated pyroptosis in the renal tissue of children with congenital hydronephrosis (CHn). Methods We detected the expression character…
View article: Unilateral Suprainguinal Ectopic Scrotum: Case Report and Literature Review
Unilateral Suprainguinal Ectopic Scrotum: Case Report and Literature Review Open
Ectopic scrotum is an infrequent congenital scrotal anomaly. Different surgical methods of correcting ectopic scrotum have been used, but none have produced optimal cosmetic results for all types. We describe a case of left ectopic suprain…
View article: Laparoscopic versus robot-assisted pyeloplasty in infants and young children
Laparoscopic versus robot-assisted pyeloplasty in infants and young children Open
RALP has the advantages of less trauma and faster recovery. It can be safely and effectively performed in infants and young children, and its effectiveness is similar to that of traditional LP.
View article: Novel compound heterozygous mutations in the desert hedgehog (DHH) gene in cases of siblings with 46,XY disorders of sexual development
Novel compound heterozygous mutations in the desert hedgehog (DHH) gene in cases of siblings with 46,XY disorders of sexual development Open
View article: Mental health status of children with disorders of sexual development and their correlates
Mental health status of children with disorders of sexual development and their correlates Open
Disorders of sexual development (DSD) refer to the congenital abnormalities of chromosomes, gonads, or gender anatomy. Children with DSD usually experience more stress. The present study aims to evaluate the mental health status of childre…
View article: Histopathological Features of Vanishing Testes in 332 Boys: What Is Its Significance? A Retrospective Study From a Tertiary Hospital
Histopathological Features of Vanishing Testes in 332 Boys: What Is Its Significance? A Retrospective Study From a Tertiary Hospital Open
The purpose of this study is to analyze the histopathological features of resected testicular remnant specimens, ascertain the incidence of the presence of either germ cells (GCs) or seminiferous tubules (SNTs), and assess whether surgical…
View article: Surgical management and molecular diagnosis of persistent Müllerian duct syndrome in Chinese patients
Surgical management and molecular diagnosis of persistent Müllerian duct syndrome in Chinese patients Open
Persistent Müllerian duct syndrome (PMDS) is a rare clinically and genetically overlapping disorder caused by mutations in the anti-Müllerian hormone ( AMH ) gene or the anti-Müllerian hormone receptor type 2 ( AMHR2 ) gene. Affected indiv…
View article: The Characteristics and Distribution of Nerve Plexuses in the Dartos Fascia From Concealed Penis Children
The Characteristics and Distribution of Nerve Plexuses in the Dartos Fascia From Concealed Penis Children Open
The purpose of this study is to analyze the nerve plexus distribution in dartos fascia of concealed penis (CP). A total of 28 CP patients met ASA categories I and II were included, with median age of 3.5 years (8 months−5 years). During th…
View article: Asymptomatic obstructive hydronephrosis associated with diabetes insipidus: a case report and review
Asymptomatic obstructive hydronephrosis associated with diabetes insipidus: a case report and review Open
The treatment of asymptomatic hydronephrosis due to ureteropelvic junction obstruction (UPJO), as well as the timing and indications for surgical intervention, remain controversial. Diabetes insipidus (DI) is a rare disease in infants that…
View article: Management and Molecular Diagnosis of Persistent Müllerian Duct Syndrome in Chinese Patients
Management and Molecular Diagnosis of Persistent Müllerian Duct Syndrome in Chinese Patients Open
Background: To report the management and molecular findings of patients with persistent Müllerian duct syndrome (PMDS). Materials and Methods: The hospital records of PMDS patients seen in our center between 2012 and 2020 were retrospectiv…
View article: Splenogonadal fusion: a case report and review of the literature
Splenogonadal fusion: a case report and review of the literature Open
Background Splenogondal fusion (SGF) is a rare congenital anomaly characterized by abnormal association between the splenic tissue and the gonads or mesonephric remnants. SGF that requires separate two-stage laparoscopic staged Fowler-Step…
View article: Identification of risk factors associated with numerous reoperations following primary hypospadias repair
Identification of risk factors associated with numerous reoperations following primary hypospadias repair Open
Severe recurrent ventral curvature, urethral stricture, dehiscence and primary staged hypospadias repair were associated with numerous reoperations following primary hypospadias repair.
View article: Preoperative transcatheter arterial chemoembolization (TACE) and systemic chemotherapy for treatment of wilms’ tumor with atrial tumor thrombus: One case report
Preoperative transcatheter arterial chemoembolization (TACE) and systemic chemotherapy for treatment of wilms’ tumor with atrial tumor thrombus: One case report Open
View article: Renal malignant tumor with the loss of INI1 expression and WT1 positive in a 3-year-old boy: a case report
Renal malignant tumor with the loss of INI1 expression and WT1 positive in a 3-year-old boy: a case report Open
Wilms' tumor is the most common primary renal malignancy in children (80%) and the less common tumors include renal cell carcinoma, rhabdoid tumor, clear cell sarcoma, cellular congenital mesoblastic nephroma and medullary carcinoma, all o…
View article: Assessment of The Nerve Ending Distributions on Dartos Fascia in Children with Concealed Penises
Assessment of The Nerve Ending Distributions on Dartos Fascia in Children with Concealed Penises Open
Background: The role of nerve ending distribution indartos fascia in the pathogenesis of concealed penis (CP) is still unclear. Our aim is to compare the histological structure of dartos fascia of both normal and CP tissue to evaluate the …
View article: Prevention and control strategies for emergency, limited-term, and elective operations in pediatric surgery during the epidemic period of COVID-19
Prevention and control strategies for emergency, limited-term, and elective operations in pediatric surgery during the epidemic period of COVID-19 Open
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to more than 100 countries. Children approved to be susceptible to SARS-CoV-2 infection. Preventing and c…
View article: Infantile synchronous primary bilateral testicular germ cell tumor: a case report and review of the literature
Infantile synchronous primary bilateral testicular germ cell tumor: a case report and review of the literature Open
Testicular tumors are uncommon in adults, accounting for <1% of all cancers, with testicular germ cell tumors (TGCTs) representing the majority (>95%) of reported cases. Adult and prepubertal TGCTs are fundamentally distinct and the latter…
View article: Current treatment for Wilms tumor: COG and SIOP standards
Current treatment for Wilms tumor: COG and SIOP standards Open
Background Wilms tumor (WT) is the most common renal malignant tumor in children. It occurs primarily at preschool age. The purpose of this review is to present current standards of diagnosis and treatment of WT around the world. Data sour…
View article: [Fetal anteroposterior renal pelvic diameter for predicting antenatal hydronephrosis requiring postnatal surgery].
[Fetal anteroposterior renal pelvic diameter for predicting antenatal hydronephrosis requiring postnatal surgery]. Open
APD in pregnancy can be used to predict whether the fetus with hydronephrosis needs surgical treatment after birth, and the prediction value of APD in the middle pregnancy is better.
View article: Treatment efficacy of tolterodine versus belladonna mixture in children with idiopathic overactive bladder
Treatment efficacy of tolterodine versus belladonna mixture in children with idiopathic overactive bladder Open
Objectives Children with symptoms of urinary urgency, frequency and incontinence are common in the clinic. The aim of the present study was to compare the tolerability and efficacy of tolterodine, a bladder-selective muscarinic receptor an…
View article: [Progress on evaluation, diagnosis and management of disorders of sex development].
[Progress on evaluation, diagnosis and management of disorders of sex development]. Open
Disorders of sex development (DSD) refer to a group of diseases characterized by abnormal congenital development of chromosomes, gonad or genitals with different pathophysiological changes and clinical manifestations. DSD is more common in…
View article: Irf5 deficiency in myeloid cells prevents necrotizing enterocolitis by inhibiting M1 macrophage polarization
Irf5 deficiency in myeloid cells prevents necrotizing enterocolitis by inhibiting M1 macrophage polarization Open
Necrotizing enterocolitis (NEC) is a life-threatening inflammatory disease in newborns, but the mechanisms remain unclear. Interferon regulatory factor 5 (IRF5) is a master regulator of macrophage function and is essential for proinflammat…
View article: Width proportion of the urethral plate to the glans can serve as an appraisal index of the urethral plate in hypospadias repair
Width proportion of the urethral plate to the glans can serve as an appraisal index of the urethral plate in hypospadias repair Open
Objectives To find a new appropriate evaluation for urethral plate quality in hypospadias repair, with particular interest in the width proportion of the urethral plate to the glans, serving as an appraisal index. Methods Data were prospec…
View article: Neoadjuvant Transcatheter Arterial Chemoembolization and Systemic Chemotherapy for the Treatment of Wilms Tumor
Neoadjuvant Transcatheter Arterial Chemoembolization and Systemic Chemotherapy for the Treatment of Wilms Tumor Open
From 2003 to 2013, 55 patients (median age 3.3 years; 29 males, 26 females) with unresectable, metastatic, or diffuse anaplastic histology (AH) Wilms tumor were treated with neoadjuvant transcatheter arterial chemoembolization (TACE) and s…
View article: Prognostic value of three-dimensional ultrasound for fetal hydronephrosis
Prognostic value of three-dimensional ultrasound for fetal hydronephrosis Open
The present study evaluated the prognostic value of three-dimensional ultrasound for fetal hydronephrosis. Pregnant females with fetal hydronephrosis were enrolled and a novel three-dimensional ultrasound indicator, renal parenchymal volum…