Explanipedia

Integration of single-cell and bulk transcriptomics to explore prognostic and immunotherapeutic characteristics of sodium overload-induced cell death in lung adenocarcinoma Open

Yilun Shi, Xiangyu Qu, Dayu Liu, Huihong Zhang, Suchen Wang , et al. · 2025

The prognostic model developed from NECSOs enables robust survival prediction for LUAD patients and provides insights into the immune landscape of LUAD. Notably, epithelial cells with higher NECSOs scores displayed a greater propensity for…

Vehicle-to-everything decision optimization and cloud control based on deep reinforcement learning Open

Zhenhai Gao, Dayu Liu, Chengyuan Zheng · 2025

A case of hypopharyngeal cancer with delayed suboccipital lymph node metastasis: Case report Open

Jianlin Yue, Huidong Zhang, Zheng Jiang, Bo Fu, Ruijie Sun , et al. · 2024

During follow-up, close monitoring of lymph nodes outside the primary tumor drainage area is crucial for patients with severe cervical lymph node metastasis of hypopharyngeal cancer.

Laryngeal Neuroendocrine Neoplasms: Analysis of 11 Cases in a Single-Center Study Open

Jianlin Yue, Qianqian Zhao, Suyuan Sun, Xinliang Pan, Dayu Liu · 2024

Objective: Laryngeal neuroendocrine neoplasms (LNEN) are rare, and there have been previous uncertainties regarding their classification and treatment modalities. This article aims to share our treatment experience, elucidate changes in LN…

Enabling an Inorganic-Rich Interface via Cationic Surfactant for High-Performance Lithium Metal Batteries Open

Zejun Sun, Jinlin Yang, Hongfei Xu, Chonglai Jiang, Yuxiang Niu , et al. · 2024

An anion-rich electric double layer (EDL) region is favorable for fabricating an inorganic-rich solid–electrolyte interphase (SEI) towards stable lithium metal anode in ester electrolyte. Herein, cetyltrimethylammonium bromide (CTAB), a ca…

Predictive Value of AMH on Spontaneous Abortion: Systematic Review and Meta-analysis Open

R. Yao, Dayu Liu, Chang Liu, Xinyu Han, Xiaoling Feng · 2024

Objective: To systematically evaluate the predictive value of anti-Mullerian hormone (AMH) in relation to spontaneous abortion (SA), taking into consideration the variables of age and conception mode. Methods: We searched electronic databa…

Programmable droplet microfluidics for complex multistep bioassays Open

Enqi Huang, Yu Wang, Dongyang Cai, Dayu Liu · 2024

Programmable droplet microfluidics (PDM) refers to a microfluidic device that integrates the functionality of a series of droplets with distinct spatial locations in a designated temporal order. PDM streamlines the intricate workflow of co…

Liquid–Liquid Two-Phase Flow and Size Prediction of Slug Droplets in Microchannels Open

Wei Du, Yingfeng Duan, Lina Wang, Dayu Liu · 2023

The liquid–liquid two-phase flow and size prediction of slug droplets in flow-focusing microchannels with different downstream orifice sizes were investigated experimentally. Aqueous solution of 50%-glycerol and mineral oil with 4 wt.% sur…

Droplet Encoding‐Pairing Enabled Multiplexed Digital Loop‐Mediated Isothermal Amplification for Simultaneous Quantitative Detection of Multiple Pathogens Open

Dongyang Cai, Yu Wang, Jingjing Zou, Zhujun Li, Enqi Huang , et al. · 2023

Despite the advantages of digital nucleic acid analysis (DNAA) in terms of sensitivity, precision, and resolution, current DNAA methods commonly suffer a limitation in multiplexing capacity. To address this issue, a droplet encoding‐pairin…

Therapeutic effect on pyriform sinus carcinoma resection via paraglottic space approach Open

Lei Wang, Dayu Liu, Ruijie Sun, Zhen Jiang, Jianlin Yue · 2023

Objective To analyse the surgical indications, surgical efficacy and key influencing factors of prognosis of using a novel surgical approach for pyriform sinus carcinoma resection utilising the paraglottic space. Methods From 2014 to 2017,…

<span>TMEM184B</span> promotes proliferation, migration and invasion, and inhibits apoptosis in hypopharyngeal squamous cell carcinoma Open

Yun Lin, Dayu Liu, Xuexin Li, Yan Ma, Xinliang Pan · 2022

Several members of the transmembrane protein family are associated with the biological processes of human malignancies; however, the expression pattern and biological function of one family member, TMEM184B, in hypopharyngeal squamous cell…

Droplet breakup in the square microchannel with a short square constriction to generate slug flow Open

Xiaoda Wang, Yuanyuan Liu, Dayu Liu, Xue-Hui Ge, Ling Li , et al. · 2022

Droplet breakup in micro-constrictions is an important phenomenon in industrial applications. This work aimed to investigate the droplet breakup in the square microchannel with a short square constriction to generate the slug flow, which d…

Realization of indoor and outdoor localization and navigation for quadruped robots Open

Xin Chen, Dayu Liu, Jiangtao Luo, Teng Chen, Guoteng Zhang , et al. · 2022

The quadruped robot has the advantages of flexible movement and large load because of the bionic leg structure. In order to improve their intelligence and autonomy in the complex environment, we build a highly integrated sensing system wit…

Cascade Filtration and Droplet Digital Detection Integrated Microfluidic Assay Enables I Solating C Ulture-Free Phenotypic Identification of Carbapenem-Resistant Organisms Open

Yu Wang, Xiuyun Ouyang, Haoyan He, Yunfan Liu, Jingjing Zou , et al. · 2022

A novel surgical approach for hypopharyngeal carcinoma resection via the paraglottic space Open

Wenming Li, Dongmin Wei, Ye Qian, Shengda Cao, Dayu Liu , et al. · 2021

A fully automated microfluidic PCR-array system for rapid detection of multiple respiratory tract infection pathogens Open

Enqi Huang, Yu Wang, Na Yang, Bowen Shu, Guohao Zhang , et al. · 2021

Multifunctional microfluidic chip for cancer diagnosis and treatment Open

Qiaoru Guo, Lingling Zhang, Jifang Liu, Zhen Li, Jia-jun Li , et al. · 2020

Microfluidic chip is not a chip in the traditional sense. It is technologies that control fluids at the micro level. As a burgeoning biochip, microfluidic chips integrate multiple disciplines, including physiology, pathology, cell biology,…

Clinical value of ultrasonic imaging in diagnosis of hypopharyngeal cancer with cervical lymph node metastasis Open

Guzi Wang, Xiaoguang Li, Li Li, Dayu Liu, Ruijie Sun , et al. · 2019

Clinical value of ultrasonic imaging in diagnosis of hypopharyngeal cancer with cervical lymph node metastasis was investigated. Eighty-nine patients who were diagnosed with hypopharyngeal cancer in Qilu Hospital of Shandong University (Qi…

Table of Contents Open

Hanzhe Li, Xiaodong Zhang, Zhufeng Lu, Rui Li, Yong Song , et al. · 2019

The algebraic solution to the spherical 4R function generator for six precision points

GE11 peptide-conjugated nanoliposomes to enhance the combinational therapeutic efficacy of docetaxel and siRNA in laryngeal cancers Open

Weiwei Xu, Dayu Liu, Yingchun Cao, Xiangyun Wang · 2017

In this study, dual therapeutic-loaded GE11 peptide-conjugated liposomes were developed and applied to enhance therapeutic efficacies of standard-of-care regimens for the treatment of laryngeal cancer. The therapeutic strategy used here wa…

<strong>Patient-Specific Microfluidic Elasto-Filtration (psMEF) CTC Technology for Cancer Diagnosis via Synergy between Nonlinear Dynamic System Engineering and Clinical Data</strong> Open

Yi-Kuen Lee, Cong Zhao, Huahuang Luo, Dayu Liu, Wenjuan Ma , et al. · 2017

Early cancer diagnosis, critical to the increase survival rate of cancer patients, is still challenging although to date more than 745,000 relevant published research articles (Google Scholar database) and more than 346,000 articles (PubMe…

Upregulation of the long noncoding RNA UCA1 affects the proliferation, invasion, and survival of hypopharyngeal carcinoma Open

Ye Qian, Dayu Liu, Shengda Cao, Ye Tao, Dongmin Wei , et al. · 2017

Taken together, our findings for the first time identify the role of UCA1 as a tumor promoter and a pro-metastatic factor in HSCC, demonstrating that UCA1 is a potential prognostic biomarker and therapeutic target in HSCC.

Ultrasensitive detection of serum hepatitis B virus by coupling ultrafiltration DNA extraction with real-time PCR Open

Bin Wu, Feng Xiao, Pei-Wen Li, Yan Du, Jinqiong Lin , et al. · 2017

The UF-qPCR assay is reliable, highly sensitive, affordable and time-saving, and the method can be used for ultrasensitive detection of serum HBV.

Down syndrome critical region 1 positively correlates with angiogenesis in hypopharyngeal cancer Open

Chao Lv, Dayu Liu, Xiaona Wei · 2016

Hypopharyngeal carcinoma has one of the highest mortality rates of head and neck cancer, therefore, the identification of markers associated with the pathogenesis and development of hypopharyngeal cancer is critical. Down syndrome critical…

The effect and mechanism of action of metformin on in vitro FaDu cell proliferation Open

Ruijie Sun, Xiaojie Ma, Xiaolan Cai, Xinliang Pan, Dayu Liu · 2016

Objective To investigate the effect and mechanism of action of metformin on proliferation of a human hypopharyngeal carcinoma cell line (FaDu). Methods FaDu cells were treated with metformin (25–125 mmol/l). Cell proliferation was evaluate…

Overall survival with and without laryngeal function preservation in 580 patients with hypopharyngeal squamous cell carcinoma Open

Jieyu Zhou, Yongmei Li, Dongmin Wei, Ye Qian, Wenming Li , et al. · 2015

The aims of the present study were to review the experience of different surgical reconstruction methods for hypopharyngeal squamous cell carcinoma (HSCC) and compared the survival of patients with and without laryngeal function (LF) prese…

Chloroquine-Enhanced Efficacy of Cisplatin in the Treatment of Hypopharyngeal Carcinoma in Xenograft Mice Open

Xingguo Zhao, Ruijie Sun, Xiaoyan Yang, Dayu Liu, Dapeng Lei , et al. · 2015

Hypopharyngeal squamous cell carcinoma (HSCC) has the worst prognosis among head and neck cancers. Cisplatin (DDP)-based chemotherapy is an important part of multimodal treatments. However, resistance to DDP severely impairs the effectiven…

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