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View article: Health-related quality of life and psychosocial outcomes in long-term survivors treated with immune checkpoint inhibitors: a nationwide multicenter study
Health-related quality of life and psychosocial outcomes in long-term survivors treated with immune checkpoint inhibitors: a nationwide multicenter study Open
Background The increasing use of immune checkpoint inhibitors (ICIs) has resulted in a growing population of long-term survivors (LTS). However, the long-term psychosocial and quality of life (QoL) outcomes in these patients remain underex…
Induction chemotherapy followed by definitive chemoradiation in patients with inoperable esophageal squamous cell carcinoma: a multicenter retrospective study Open
Induction chemotherapy followed by CRT showed significantly improved DMFS and a trend towards improved DFS and OS in inoperable ESCC, particularly prominent in patients with more advanced T (T3-T4) or TNM (III-IV) stages.
View article: Correction: Kalkan et al. Efficacy of Immunotherapy Versus Chemotherapy in Advanced Pleural Mesothelioma: A Turkish Oncology Group (TOG) Study. Medicina 2025, 61, 638
Correction: Kalkan et al. Efficacy of Immunotherapy Versus Chemotherapy in Advanced Pleural Mesothelioma: A Turkish Oncology Group (TOG) Study. Medicina 2025, 61, 638 Open
In the original publication, there was a mistake in Figure 2 as published [...]
The Prognostic Value of EGFR Amplifications in Head and Neck Squamous Cell Carcinoma Open
Objective: The epidermal growth factor receptor (EGFR) pathway plays a crucial role in head and neck squamous cell carcinoma (HNSCC) carcinogenesis, and alterations in this pathway have been explored as potential prognostic biomarkers. Thi…
The lactate dehydrogenase-to-albumin ratio is a prognostic biomarker in extensive-stage small-cell lung cancer Open
Background: The lactate dehydrogenase-to-albumin ratio (LAR) is a promising prognostic marker in various malignancies. However, its clinical relevance in extensive-disease small-cell lung cancer (ED-SCLC) remains unclear. Methods: We analy…
Gender Medicine in Computed Tomography Radiomics Analysis to Predict Disease Progression in Liver Respectable Colorectal Cancer Patients Open
Background Gender medicine is an evolving discipline that examines how diseases manifest and progress differently in men and women. Tailoring medical therapies and diagnostic approaches can enhance patient outcomes. While radiomics is emer…
Are we closing the gender gap in academic oncology? An observational study of gender disparities in participant engagement at the ASCO 2024 annual meeting Open
Objective Despite global efforts, gender disparities in oncology may persist. Understanding these disparities within the context of major conferences can inform strategies to promote gender inclusiveness in the field. This study evaluates …
Research training, barriers, and career development needs of early-career investigators in oncology: an EORTC survey-based study Open
Background: The increasing complexity of cancer research presents significant challenges for early-career oncologists in establishing independent research careers. Although dedicated support platforms have emerged in recent years, a thorou…
View article: HER2-low expression in patients with hormone receptor positive and HER2 negative advanced breast cancer treated with ribociclib or palbociclib in combination with endocrine therapy
HER2-low expression in patients with hormone receptor positive and HER2 negative advanced breast cancer treated with ribociclib or palbociclib in combination with endocrine therapy Open
Aim: Hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative breast cancer which represents the most common subgroup of metastatic breast cancer (MBC). Recently, further subclassification for HER2-negative tumors ha…
Prognostic Nutritional Index and a Blood-Based Prognostic Tool in Prostate Cancer Treated with Abiraterone, Enzalutamide or Cabazitaxel Open
Background and Objectives: The prognostic nutritional index (PNI), a marker reflecting both nutritional and immune status, has been associated with prognosis in various malignancies. However, evidence in metastatic castration-resistant pro…
Pediatricians’ Knowledge, Attitudes and Practices Regarding Childhood Eye Diseases Open
Objective: Pediatricians’ knowledge, attitudes, and practices regarding the etiology of eye diseases play a critical role in the early diagnosis of these conditions and in referring patients to ophthalmologists when necessary. The aim of t…
Prognostic and predictive significance of the pan-immune-inflammation value in endometrial cancer patients undergoing adjuvant therapy Open
The PIV score is a significant prognostic marker for survival in endometrial cancer patients receiving adjuvant chemotherapy. Patients with a high PIV score may benefit from the addition of radiotherapy to their treatment regimen. Further …
Treatment-Related Adverse Events in Extended Stage Small Cell Lung Cancer Patients Receiving First-Line Chemoimmunotherapy Versus Chemotherapy Alone: A Systematic Review and Meta-Analysis Open
Introduction: Nowadays the prognosis of extended stage (ES) small cell lung cancer (SCLC) patients is poor. However, a high response rate to first-line chemotherapy (CT) and the addition of immune checkpoint inhibitors (ICIs) have notably …
Early Changes in Volumetric Body Composition Parameters Predict Survival Outcomes in Patients with Metastatic Renal Cell Carcinoma Treated with Targeted Therapy Open
Background/Objectives: The precise role of volumetric body composition (VBC) parameters, visceral adipose tissue index (VATI), subcutaneous adipose tissue index (SATI), and skeletal muscle index (SMI) on the survival of metastatic renal ce…
Breast Radiotherapy: A Potential Risk Factor for Resistant Clone Development in Patients with Brain Metastasis Open
Objective: The human brain is a frequent site of breast cancer metastasis. The various therapeutic approaches for treating brain metastases include surgical intervention, stereotactic radiosurgery (SRS), and whole-brain radiotherapy (WBRT)…
Clinical Characteristics and Management of Patients Admitted to the Supportive Care Clinic and Predisposing Factors of Unplanned Hospital Readmission: Single-Center Experience Open
Background: It is well known that supportive care clinics are vital in medical oncology practice. This study aims to present a portrait of the supportive care clinic of a tertiary cancer center in a low-middle-income country. Methods: This…
View article: Efficacy of Second-Line Treatments After Atezolizumab and Bevacizumab in Advanced Hepatocellular Carcinoma and Related Prognostic Factors: A Multicenter Study by the Turkish Oncology Group (TOG)
Efficacy of Second-Line Treatments After Atezolizumab and Bevacizumab in Advanced Hepatocellular Carcinoma and Related Prognostic Factors: A Multicenter Study by the Turkish Oncology Group (TOG) Open
Background/Aims: The treatment of hepatocellular carcinoma (HCC), which accounts for 90% of all liver cancers, is highly varied. The use of second-line treatments following progression on first-line atezolizumab and bevacizumab (Atez/Bev) …
View article: Efficacy of Immunotherapy Versus Chemotherapy in Advanced Pleural Mesothelioma: A Turkish Oncology Group (TOG) Study
Efficacy of Immunotherapy Versus Chemotherapy in Advanced Pleural Mesothelioma: A Turkish Oncology Group (TOG) Study Open
Background and Objectives: This study aimed to evaluate the effectiveness of immunotherapy compared to chemotherapy across different treatment lines in patients with pleural mesothelioma. It also sought to identify factors influencing the …
Fear of Cancer Recurrence and Associated Factors in Lymphoma Survivors and Their Family Caregivers: A Cross‐Sectional Study Open
Background Fear of cancer recurrence (FCR) is a pervasive concern among lymphoma survivors and their family caregivers, influencing psychological and physical health. Given the substantial burden of FCR, identifying its predictors is cruci…
Comparative Analysis of Prognostic Potential of Pretreatment Blood-Based Biomarkers in Metastatic Bladder Cancer: Modified Glasgow Prognostic Score Open
Background: Metastatic bladder cancer (mBC) presents a significant global health challenge with a poor prognosis and considerably limited survival. Despite advancements in therapies, long-term survival remains difficult to predict. This st…
View article: Efficacy of Immunotherapy Versus Chemotherapy in Advanced Malignant Pleural Mesothelioma: A Multicentre Retrospective Study in Turkiye
Efficacy of Immunotherapy Versus Chemotherapy in Advanced Malignant Pleural Mesothelioma: A Multicentre Retrospective Study in Turkiye Open
Background and Objectives: This study aimed to evaluate the effectiveness of immunotherapy compared to chemotherapy across different treatment lines in patients with malignant pleural mesothelioma. It also sought to identify factors influe…
Serum Albumin–Creatinine Ratio and Anthracycline Cardiotoxicity in Patients with Cancer Open
Background: Several studies have suggested that the serum albumin–creatinine ratio (sACR) is a useful marker for the early risk stratification of patients with cardiomyocyte injury. This study aims to evaluate the relationship between sACR…
View article: Activity of CDK4/6 inhibitors and parameters affecting survival in elderly patients in age-subgroups: Turkish Oncology Group (TOG) retrospective study
Activity of CDK4/6 inhibitors and parameters affecting survival in elderly patients in age-subgroups: Turkish Oncology Group (TOG) retrospective study Open
Highly selective inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6is) have emerged as a standart of care for first- and second-line therapies in combination with endocrine therapy (ET) for HR+/HER2- metastatic breast cancer (MBC) patie…
Monitoring Over Time of Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer Patients Through an Ensemble Vision Transformers‐Based Model Open
Background Morphological and vascular characteristics of breast cancer can change during neoadjuvant chemotherapy (NAC). Dynamic contrast‐enhanced magnetic resonance imaging (DCE‐MRI)‐acquired pre‐ and mid‐treatment quantitatively capture …
Sex differences in adverse events among cancer patients receiving immune checkpoint inhibitors: the MOUSEION-07 systematic review and meta-analysis Open
Immune checkpoint inhibitors have revolutionized cancer treatment, but they are associated with a range of immune-related adverse events (irAEs), and emerging evidence suggests significant sex differences in the incidence, type, and severi…