Dea Nagy
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View article: Histopathological and Molecular Predictors of the First Site of Dissemination in Non-Small Cell Lung Cancer
Histopathological and Molecular Predictors of the First Site of Dissemination in Non-Small Cell Lung Cancer Open
Background: Non-small-cell lung cancer (NSCLC) is often diagnosed at stage IV, when prognosis depends on metastatic spread. The impact of histopathology on the first metastatic site remains underexplored. Methods: We retrospectively analyz…
View article: Differential activation of the inositol 5-phosphatase SHIP2 by EGF and insulin signaling pathways
Differential activation of the inositol 5-phosphatase SHIP2 by EGF and insulin signaling pathways Open
The importance of phosphatidylinositol 3,4,5- trisphosphate (PIP3) in cell signaling has been well established. Despite phosphatidylinositol 3,4-bisphosphate [PI(3,4)P2] emerging as an actor independent of PIP3, its exact signaling role re…