Explanipedia

Outcomes of surgically and non-surgically managed temporal encephalocoeles in the context of drug-resistant temporal lobe epilepsy: A retrospective single-centre case series Open

Anca-Mihaela Vasilica, Jasneet Dhaliwal, Debayan Dasgupta, Ajai Chari, Sachit Shah , et al. · 2025

Our study demonstrates that excellent post-operative outcomes are achievable with temporal lobe resections. A standardised presurgical evaluation pathway and management protocol are essential to ensure timely identification of temporal enc…

965 "Write Between the Eyes: A Pencil Injury Through the Superior Orbital Fissure and Into the Temporal Lobe in a 4-Year-Old" Open

J Panascia, Debayan Dasgupta · 2025

Penetrating orbital injuries in children are rare but can result in severe complications, particularly when associated with intracranial involvement. This case report details the management of a child who sustained a pencil injury to the l…

1093 Mandibular Swelling as the First Sign: A Rare Case of Tuberculous Osteomyelitis Open

Cao Chua, Debayan Dasgupta, Navin Vig · 2025

Tuberculous (TB) osteomyelitis of the mandible is exceedingly rare, constituting less than 2% of all skeletal tuberculosis cases. This case report describes the initial presentation of a patient with tuberculosis manifesting as swelling as…

Computer-assisted stereoelectroencephalography planning: center-specific priors enhance planning Open

Debayan Dasgupta, Cameron Elliott, Aidan G. O’Keeffe, Roman Rodionov, Kuo Li , et al. · 2025

Objectives This study aims to refine computer-assisted planning (CAP) of SEEG implantations by adding spatial constraints from prior SEEG trajectories (“Priors”) to improve safety and reduce manual adjustments, without increasing planning …

Refining computer-assisted SEEG planning with spatial priors – A novel comparison of implantation strategies across adult and paediatric centres Open

Debayan Dasgupta, Ajai Chari, Mehdi Khan, Friederike Moeller, Muhammad Zubair Tahir , et al. · 2025

The use of centre-specific spatial priors allows the incorporation of surgeon-specific and unit-specific preferences into automated planning. We compare implantation styles between a paediatric and an adult centre, discussing similarities …

The flow of ideas in word embeddings Open

Debayan Dasgupta · 2023

The flow of ideas has been extensively studied by physicists, psychologists, and machine learning engineers. This paper adopts specific tools from microrheology to investigate the similarity-based flow of ideas. We introduce a random walke…

Extent of piriform cortex resection in children with temporal lobe epilepsy Open

Rory J. Piper, Debayan Dasgupta, Maria H. Eriksson, Mathilde Ripart, Asweel K Moosa Asweel K Moosa , et al. · 2023

Objective A greater extent of resection of the temporal portion of the piriform cortex (PC) has been shown to be associated with higher likelihood of seizure freedom in adults undergoing anterior temporal lobe resection (ATLR) for drug‐res…

Thalamostriatal disconnection underpins long-term seizure freedom in frontal lobe epilepsy surgery Open

Davide Giampiccolo, Lawrence P. Binding, Lorenzo Caciagli, Roman Rodionov, Chris Foulon , et al. · 2023

Around 50% of patients undergoing frontal lobe surgery for focal drug-resistant epilepsy become seizure free post-operatively; however, only about 30% of patients remain seizure free in the long-term. Early seizure recurrence is likely to …

Contribution of White Matter Fiber Bundle Damage to Language Change After Surgery for Temporal Lobe Epilepsy Open

Lawrence P. Binding, Debayan Dasgupta, Peter N. Taylor, Pamela J. Thompson, Aidan G. O’Keeffe , et al. · 2023

We demonstrate a relationship between fiber transection and naming decline after temporal lobe resection. Individualized surgical planning to spare white matter fiber bundles could help to preserve language function after surgery.

Hippocampal resection in temporal lobe epilepsy: Do we need to resect the tail? Open

Debayan Dasgupta, Roisin Finn, Ajai Chari, Davide Giampiccolo, Jane de Tisi , et al. · 2023

Elasticity can affect droplet coalescence Open

Sarath Chandra Varma, Debayan Dasgupta, Aloke Kumar · 2022

Coalescence of two droplets on a solid substrate is an interfacial phenomenon that imposes the challenges of capturing the complex contact line motion and energy interaction between the solid–liquid interface. Recent investigations on the …

Previous, current, and future stereotactic EEG techniques for localising epileptic foci Open

Debayan Dasgupta, Anna Miserocchi, Andrew W. McEvoy, John S. Duncan · 2022

We provide a perspective on the future directions in the field, reviewing improvements in predicting electrode bending, image acquisition, machine learning and artificial intelligence, advances in surgical planning and visualization softwa…

Mobile Nanobots for Prevention of Root Canal Treatment Failure (Adv. Healthcare Mater. 14/2022) Open

Debayan Dasgupta, Shanmukh Peddi, Deepak Kumar Saini, Ambarish Ghosh · 2022

Root Canal Treatment Root canal treatments fail due to remnant bacteria in the tubules of the dentine tissue of human teeth. In article number 2200232 by Ambarish Ghosh and co-workers, magnetic nanobots can target pathogens deep inside the…

Structure and function of language networks in temporal lobe epilepsy Open

Lawrence P. Binding, Debayan Dasgupta, Davide Giampiccolo, John S. Duncan, Sjoerd B. Vos · 2022

Individuals with temporal lobe epilepsy (TLE) may have significant language deficits. Language capabilities may further decline following temporal lobe resections. The language network, comprising dispersed gray matter regions interconnect…

Nanorobots Sense Local Physiochemical Heterogeneities of Tumor Matrisome Open

Debayan Dasgupta, Dharma Pally, Deepak Kumar Saini, Ramray Bhat, Ambarish Ghosh · 2020

The dissemination of cancer is brought about by continuous interaction of malignant cells with their surrounding tissue microenvironment. Understanding and quantifying the remodeling of local extracellular matrix (ECM) by invading cells ca…

Targeting chondroitinase ABC to axons enhances the ability of chondroitinase to promote neurite outgrowth and sprouting Open

Priscilla Day, Nuno L. Alves, Esther Daniell, Debayan Dasgupta, Rosalie Ogborne , et al. · 2020

Background: There is currently no effective treatment for promoting regeneration of injured nerves in patients who have sustained injury to the central nervous system such as spinal cord injury. Chondroitinase ABC is an enzyme, which promo…

Simulation workshops as an adjunct to perioperative care bundles in the management of external ventricular drains: improving surgical technique and reducing infection Open

Debayan Dasgupta, Linda D’Antona, Daniel Aimone Cat, Ahmed K. Toma, Carmel Curtis , et al. · 2018

OBJECTIVE Temporary CSF diversion through an external ventricular drain (EVD) comes with the risk of EVD-related infections (ERIs). The incidence of ERIs varies from 0.8% to 22%. ERIs increase mortality, morbidity, length of stay, and cost…

Trafficking and processing of bacterial proteins by mammalian cells: Insights from chondroitinase ABC Open

Elizabeth M. Muir, Mansoor Raza, Clare Ellis, Emily R. Burnside, Fiona M. Love , et al. · 2017

Background: There is very little reported in the literature about the relationship between modifications of bacterial proteins and their secretion by mammalian cells that synthesize them. We previously reported that the secretion of the ba…

Intraparenchymal intracranial pressure monitoring for hydrocephalus and cerebrospinal fluid disorders Open

Ajai Chari, Debayan Dasgupta, Alexander Smedley, Claudia Craven, Edward Dyson , et al. · 2017

This study provides insights into hydrodynamic disturbances in different diagnostic groups of patients with CSF hydrodynamic disorders. It highlights the utility of analyzing both median PA and ICP recordings, stratified into day and night…

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