Debbie Sharp
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View article: The Mistletoe and Breast Cancer (MAB) Study: A UK Mixed-Phase, Pilot, Placebo-Controlled, Double-Blind, Randomised Controlled Trial
The Mistletoe and Breast Cancer (MAB) Study: A UK Mixed-Phase, Pilot, Placebo-Controlled, Double-Blind, Randomised Controlled Trial Open
Background/Objective: To test the feasibility of a mixed-phase, pilot, placebo-controlled, double-blind trial of mistletoe therapy (MT) with an embedded qualitative study in the UK National Health Service (NHS) setting. Methods: The aim wa…
View article: The Mistletoe and Breast Cancer (MAB) Study: a UK Pilot Mixed Method, Placebo-Controlled Randomised Trial
The Mistletoe and Breast Cancer (MAB) Study: a UK Pilot Mixed Method, Placebo-Controlled Randomised Trial Open
Background/Objective: To test the feasibility of a pilot, randomised controlled trial of mistletoe therapy (MT) with an embedded qualitative study in the UK National Health Service (NHS) setting. Methods: 45 patients were recruited via an …
View article: What do complementary and alternative medicines mean to UK dairy farmers and how do they use them?
What do complementary and alternative medicines mean to UK dairy farmers and how do they use them? Open
Background Complementary and alternative medicine (CAM) is used by some farmers to support herd health management practices. There is concern by a large majority of the veterinary community, who consider CAM to be counter to evidence-based…
View article: Feasibility of engaging parents attending an adult weight management programme with child weight management support: a mixed methods study
Feasibility of engaging parents attending an adult weight management programme with child weight management support: a mixed methods study Open
Objective To explore whether parents’ attendance at a commercial adult weight management programme (WMP) offers an opportunity to identify and signpost families to child weight management support, if appropriate to a child’s weight status.…
View article: An empirical comparison of statistical methods for multiple cut-off diagnostic test accuracy meta-analysis of the Edinburgh postnatal depression scale (EPDS) depression screening tool using published results vs individual participant data
An empirical comparison of statistical methods for multiple cut-off diagnostic test accuracy meta-analysis of the Edinburgh postnatal depression scale (EPDS) depression screening tool using published results vs individual participant data Open
Background Selective reporting of results from only well-performing cut-offs leads to biased estimates of accuracy in primary studies of questionnaire-based screening tools and in meta-analyses that synthesize results. Individual participa…
View article: Generating EQ-5D-3L health utility scores from the Edinburgh Postnatal Depression Scale: a perinatal mapping study
Generating EQ-5D-3L health utility scores from the Edinburgh Postnatal Depression Scale: a perinatal mapping study Open
Background Perinatal depression (PND) describes depression experienced by parents during pregnancy or in the first year after a baby is born. The EQ-5D instrument (a generic measure of health status) is not often collected in perinatal res…
View article: Individual participant data meta-analysis to compare EPDS accuracy to detect major depression with and without the self-harm item
Individual participant data meta-analysis to compare EPDS accuracy to detect major depression with and without the self-harm item Open
Item 10 of the Edinburgh Postnatal Depression Scale (EPDS) is intended to assess thoughts of intentional self-harm but may also elicit concerns about accidental self-harm. It does not specifically address suicide ideation but, nonetheless,…
View article: Cross-sectional survey of child weight management service provision by acute NHS trusts across England in 2020/2021
Cross-sectional survey of child weight management service provision by acute NHS trusts across England in 2020/2021 Open
Objective With one in five children in England living with obesity, we mapped the geographical distribution and format of child weight management services provided by acute National Health Service (NHS) trusts across England, to identify b…
View article: 989 A cross-sectional survey of child weight management service provision by acute NHS trusts across England in 2020
989 A cross-sectional survey of child weight management service provision by acute NHS trusts across England in 2020 Open
Aims With over 20% of children in the UK living with obesity, our study aimed to map child weight management services provided by acute NHS trusts across England. The primary objectives were to identify the proportion of NHS trusts providi…
View article: Merged learning outcomes for information literacy: A David Letterman-style Top Ten List
Merged learning outcomes for information literacy: A David Letterman-style Top Ten List Open
University of Kentucky (UK) librarians are testing a new approach in the perennial quest to encourage professors and other course instructors to incorporate information literacy concepts into their course designs. Although many curricula d…
View article: A Patient Stratification Approach to Identifying the Likelihood of Continued Chronic Depression and Relapse Following Treatment for Depression
A Patient Stratification Approach to Identifying the Likelihood of Continued Chronic Depression and Relapse Following Treatment for Depression Open
Background: Subgrouping methods have the potential to support treatment decision making for patients with depression. Such approaches have not been used to study the continued course of depression or likelihood of relapse following treatme…
View article: Bariatric surgery: the GP’s role in long-term post-bariatric surgery follow-up
Bariatric surgery: the GP’s role in long-term post-bariatric surgery follow-up Open
Obesity is a well-established risk factor for a wide range of health conditions, including diabetes, cardiovascular disease, and certain cancers. The clinical importance of severe obesity (body mass index [BMI] ≥40 kg/m2) has been brought …
View article: The contribution of depressive ‘disorder characteristics’ to determinations of prognosis for adults with depression: an individual patient data meta-analysis
The contribution of depressive ‘disorder characteristics’ to determinations of prognosis for adults with depression: an individual patient data meta-analysis Open
Background This study aimed to investigate general factors associated with prognosis regardless of the type of treatment received, for adults with depression in primary care. Methods We searched Medline, Embase, PsycINFO and Cochrane Centr…
View article: Depression prevalence based on the Edinburgh Postnatal Depression Scale compared to Structured Clinical Interview for DSM DIsorders classification: Systematic review and individual participant data meta‐analysis
Depression prevalence based on the Edinburgh Postnatal Depression Scale compared to Structured Clinical Interview for DSM DIsorders classification: Systematic review and individual participant data meta‐analysis Open
Objectives Estimates of depression prevalence in pregnancy and postpartum are based on the Edinburgh Postnatal Depression Scale (EPDS) more than on any other method. We aimed to determine if any EPDS cutoff can accurately and consistently …
View article: Exploring how lifestyle weight management programmes for children are commissioned and evaluated in England: a mixed methodology study
Exploring how lifestyle weight management programmes for children are commissioned and evaluated in England: a mixed methodology study Open
Objective To assess how lifestyle weight management programmes for children aged 4–16 years in England are commissioned and evaluated at the local level. Design This was a mixed-methods study comprising an online survey and semistructured …
View article: Antidepressant treatment with sertraline for adults with depressive symptoms in primary care: the PANDA research programme including RCT
Antidepressant treatment with sertraline for adults with depressive symptoms in primary care: the PANDA research programme including RCT Open
Background Despite a growing number of prescriptions for antidepressants (over 70 million in 2018), there is uncertainty about when people with depression might benefit from antidepressant medication and concern that antidepressants are pr…
View article: Prevalence of maternal psychiatric disorder in pregnancy: 1986 and 2016
Prevalence of maternal psychiatric disorder in pregnancy: 1986 and 2016 Open
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View article: Psychological advocacy towards healing (PATH): A randomized controlled trial of a psychological intervention in a domestic violence service setting
Psychological advocacy towards healing (PATH): A randomized controlled trial of a psychological intervention in a domestic violence service setting Open
ISRCTN registry ISRCTN58561170 Original Research 3675/3750.
View article: Complementary medicine use, views, and experiences: a national survey in England
Complementary medicine use, views, and experiences: a national survey in England Open
Background In 2005,12% of the English population visited a complementary and alternative medicine (CAM) practitioner. Aim To obtain up-to-date general population figures for practitioner-led CAM use in England, and to discover people's vie…
View article: Scoping review of systematic reviews of complementary medicine for musculoskeletal and mental health conditions
Scoping review of systematic reviews of complementary medicine for musculoskeletal and mental health conditions Open
Objective To identify potentially effective complementary approaches for musculoskeletal (MSK)–mental health (MH) comorbidity, by synthesising evidence on effectiveness, cost-effectiveness and safety from systematic reviews (SRs). Design S…
View article: Sex-specific relevance of diabetes to occlusive vascular and other mortality: a collaborative meta-analysis of individual data from 980793 adults from 68 prospective studies
Sex-specific relevance of diabetes to occlusive vascular and other mortality: a collaborative meta-analysis of individual data from 980793 adults from 68 prospective studies Open
Background: Several studies have shown that diabetes confers a higher relative risk of vascular mortality among women than among men, but whether this increased relative risk in women exists across age groups and within defined levels of o…
View article: Characteristics of children who do not attend their hospital appointments, and GPs’ response: a mixed methods study in primary and secondary care
Characteristics of children who do not attend their hospital appointments, and GPs’ response: a mixed methods study in primary and secondary care Open
Background Children who do not attend (DNA) their hospital outpatient appointments are a concern because this potentially compromises the child’s health and incurs financial cost. Little is known about children who DNA or the views of GPs …