Debnarayan Dutta
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View article: Efficacy of Hippocampal Avoidance Whole Brain Radiotherapy to Preserve the Cognitive Functions among Brain Metastasis Patients: Systematic Review and Meta-analysis
Efficacy of Hippocampal Avoidance Whole Brain Radiotherapy to Preserve the Cognitive Functions among Brain Metastasis Patients: Systematic Review and Meta-analysis Open
This systematic review and meta-analysis aims to gather credible sources of comprehensive information on the efficacy and radiation dose (maximum and minimum) to the hippocampus and contouring area to prevent cognitive dysfunction by hippo…
View article: High-precision radiotherapy achieves excellent long-term control and preserves function in pediatric craniopharyngioma—Subset analysis of a randomized trial
High-precision radiotherapy achieves excellent long-term control and preserves function in pediatric craniopharyngioma—Subset analysis of a randomized trial Open
Background The evolving treatment paradigm in children and adolescents with craniopharyngioma (CP) aims at minimizing late functional sequelae. Advanced radiotherapeutic techniques offer theoretical advantages of preserving neurological fu…
View article: Feasibility of Telerehabilitation on Head and Neck Carcinoma Patients
Feasibility of Telerehabilitation on Head and Neck Carcinoma Patients Open
Background: Head and neck cancer ranks as the seventh most prevalent type of cancer globally. In patients with head and neck cancer, dysphagia leads to significant negative consequences, including difficulties in swallowing, coughing, and …
View article: Hematological Parameters at Baseline: A Novel Prognostic Factor for Cervical Cancer Patients Undergoing Concurrent Chemoradiotherapy in South India
Hematological Parameters at Baseline: A Novel Prognostic Factor for Cervical Cancer Patients Undergoing Concurrent Chemoradiotherapy in South India Open
Introduction In cervical cancer treatment, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and albumin-globulin ratio (AGR) are being studied as potential prognostic markers for predicting the effectiveness of con…
View article: Treatment Outcomes and Toxicity Profiles with PORTEC-3 Trial Regimen in South Asian Cohort of High-Risk Endometrial Cancer Patients: A Single-Center Ambispective Analysis
Treatment Outcomes and Toxicity Profiles with PORTEC-3 Trial Regimen in South Asian Cohort of High-Risk Endometrial Cancer Patients: A Single-Center Ambispective Analysis Open
Adjuvant chemoradiation followed by chemotherapy is the current standard of care in high-risk endometrial cancer after the PORTEC-3 trial. There is a lack of data on this treatment regimen in the South Asian patient cohort. The present stu…
View article: Validation of Combs prognostic scoring system in Indian recurrent glioma patients treated with re-radiation
Validation of Combs prognostic scoring system in Indian recurrent glioma patients treated with re-radiation Open
Purpose: Retrospective audit of recurrent glioma patients treated by different fractionation schedules and to validate the modified Combs prognostic score in Indian patient cohort.Material and Methods: Between Jan 2009 and June 2022, 66 re…
View article: Review of: "[Commentary] SBRT (Stereotactic Body Radiotherapy) in Recurrent Head Neck Cancer - Boon or Bane?"
Review of: "[Commentary] SBRT (Stereotactic Body Radiotherapy) in Recurrent Head Neck Cancer - Boon or Bane?" Open
Potential competing interests: No potential competing interests to declare
View article: 27P Treatment outcomes and toxicity profiles in South Asian patients of high-risk endometrial cancer treated with PORTEC-3 trial regimen
27P Treatment outcomes and toxicity profiles in South Asian patients of high-risk endometrial cancer treated with PORTEC-3 trial regimen Open
While endometrial cancers are associated with favourable outcomes due to early symptomatic evaluation, patients with high-risk features are at a higher risk of recurrence. Although results of PORTEC-3 trial established the role of concurre…
View article: Radiation Induced Liver Toxicity
Radiation Induced Liver Toxicity Open
Liver was always considered to be ‘highly sensitive’ to radiation therapy (RT) and was not considered ‘safe’ for radiation therapy treatment. The most significant radiation induced liver toxicity was described by Ingold et al. as “Radiatio…
View article: Role of Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography in Detection of Portal Vein Tumor Thrombosis in Hepatocellular Carcinoma
Role of Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography in Detection of Portal Vein Tumor Thrombosis in Hepatocellular Carcinoma Open
A 56 year old gentleman with no known comorbidities presented with pain abdomen for 1 month. Triphasic CECT abdomen showed features of cirrhosis with surface irregularities, fissural widening and volume redistribution changes in the liver.…
View article: Editorial: Novel Applications of Stereotactic Body Radiotherapy (SBRT)
Editorial: Novel Applications of Stereotactic Body Radiotherapy (SBRT) Open
EDITORIAL article Front. Oncol., 03 September 2021Sec. Radiation Oncology Volume 11 - 2021 | https://doi.org/10.3389/fonc.2021.760078
View article: Prospective evaluation of fiducial marker placement quality and toxicity in liver CyberKnife stereotactic body radiotherapy
Prospective evaluation of fiducial marker placement quality and toxicity in liver CyberKnife stereotactic body radiotherapy Open
Fiducial placement is safe and in experienced hands, "quality" of placement is "good" in majority. Major complications and admission after fiducial placement are rare. Complications, fiducial placement time, recovery time is more during th…
View article: Hippocampal radiotherapy dose constraints for predicting long-term neurocognitive outcomes: mature data from a prospective trial in young patients with brain tumors
Hippocampal radiotherapy dose constraints for predicting long-term neurocognitive outcomes: mature data from a prospective trial in young patients with brain tumors Open
Background Hippocampus is considered to be the seat for neurocognitive functions. Avoidance of hippocampus during radiotherapy to brain may serve to preserve various domains of neurocognition. We aimed to derive radiotherapy dose constrain…
View article: Prospective evaluation of fiducial migration and complications after placement for hepatocellular carcinoma treated with stereotactic body radiotherapy using cyberkinife and influence on treatment delivery: A tertiary cancer centre experience
Prospective evaluation of fiducial migration and complications after placement for hepatocellular carcinoma treated with stereotactic body radiotherapy using cyberkinife and influence on treatment delivery: A tertiary cancer centre experience Open
Background: Hepatocellular carcinoma (HCC) is the most common primary tumor of the hepatobiliary system. The Cyberknife represents a new, frameless stereotactic radiosurgery system with image-guided radiation delivery using fiducials as ma…
View article: Is it Possible to Have Meaningful Phase III Clinical Trial? Establishing Level, I Evidence May Be Counter-Productive
Is it Possible to Have Meaningful Phase III Clinical Trial? Establishing Level, I Evidence May Be Counter-Productive Open
All treatment protocols should be based on 'well-designed phase III clinical studies' and need long-term follow up in phase-IV studies (in clinical practice).These treatment protocols will give us diation or radiosurgery as a treatment opt…
View article: Comparison of Internal Target Volume (ITV) Generated with Lung Optimization Treatment (LOT) and Maximum Intensity Projection (MIP) by 4-Dimensional CT scan in Radiosurgery Treatment of Early Lung Cancer
Comparison of Internal Target Volume (ITV) Generated with Lung Optimization Treatment (LOT) and Maximum Intensity Projection (MIP) by 4-Dimensional CT scan in Radiosurgery Treatment of Early Lung Cancer Open
Background: Comparison ofinternal target volume (ITV) generated with lung optimization treatment (LOT) and 4-dimenstional computed tomography (4D-CT) measured maximum intensity projection (MIP) methods in lung tumour treatment. Materials a…
View article: Effect of Arg399Gln single-nucleotide polymorphism in XRCC1 gene on survival rate of Indian squamous cell head-and-neck cancer patients
Effect of Arg399Gln single-nucleotide polymorphism in XRCC1 gene on survival rate of Indian squamous cell head-and-neck cancer patients Open
This study suggests that HNSCC patients with Gln substitution in place of Arg at position 399 (both homozygous and heterozygous) in XRCC1 protein have significantly inferior survival functions, higher recurrence rate, and events after radi…
View article: Third time re-irradiation of liver metastasis with robotic radiosurgery: a case series
Third time re-irradiation of liver metastasis with robotic radiosurgery: a case series Open
Hepatoma Research is an open access journal and focuses on all topics related to hepatoma. The following articles are especially welcome: pathogenesis, clinical examination and early diagnosis of hepatoma, complications of hepatoma, and th…
View article: Comparison of Target Volumes in Hepatocellular Carcinoma Delineated using Standard Method and Bolus Tracking Method
Comparison of Target Volumes in Hepatocellular Carcinoma Delineated using Standard Method and Bolus Tracking Method Open
Debnarayan Dutta*, Ram Madhavan, Rupa Das, Rajesh Kannan, Anila K Raghu and Raghavandra Holla Author Affiliations Department of Radiation Oncology, India Received: May 20, 2019 | Published: May 28, 2019 Corresponding author: Debnarayan Dut…
View article: Case report on stereotactic body radiation therapy for locally recurrent renal cell carcinoma after partial nephrectomy in a patient with single kidney
Case report on stereotactic body radiation therapy for locally recurrent renal cell carcinoma after partial nephrectomy in a patient with single kidney Open
© 2019. MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work…
View article: Arteriovenous Malformation (AVM) Treated with Robotic Radiosurgery: Impact of Beam Reduction in 12 Gy Normal Brain Volume and It’s Clinical Implication
Arteriovenous Malformation (AVM) Treated with Robotic Radiosurgery: Impact of Beam Reduction in 12 Gy Normal Brain Volume and It’s Clinical Implication Open
Purpose: Dosimetric study to evaluate impact of “beam” reduction in AVM radiosurgery on normal brain dose parameters and it’s clinical implications. Materials and Methods: Five small volume AVMs (nidus volume 0.31 - 1.94 cc) planned for si…
View article: Robotic radiosurgery treatment in liver tumors: Early experience from an Indian center
Robotic radiosurgery treatment in liver tumors: Early experience from an Indian center Open
Purpose: The purpose of this study is to report CyberKnife experience in hepatocellular carcinoma (HCC) and liver metastasis (LM). Materials and Methods: Fifty liver lesions in 31 consecutive patients with liver lesion [mean age 54.5 years…
View article: CRAN-30. HIGH PRECISION STEREOTACTIC CONFORMAL RADIOTHERAPY (SCRT) IMPROVES THE LONG TERM FUNCTIONAL OUTCOME IN CHILDREN AND ADOLESCENT PATIENTS OF CRANIOPHARYNGIOMA: DATA FROM A PROSPECTIVE RANDOMIZED TRIAL
CRAN-30. HIGH PRECISION STEREOTACTIC CONFORMAL RADIOTHERAPY (SCRT) IMPROVES THE LONG TERM FUNCTIONAL OUTCOME IN CHILDREN AND ADOLESCENT PATIENTS OF CRANIOPHARYNGIOMA: DATA FROM A PROSPECTIVE RANDOMIZED TRIAL Open
BACKGROUND: To compare the clinical and functional outcome in young patients with craniopharyngioma treated with Stereotactic Conformal focal radiotherapy (SCRT) and conventional RT(ConvRT). METHODS: Patients were assigned to either SCRT o…