Deborah E. Burgin
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View article: Differential Effects of Two Lots of Aroclor 1254 on Enzyme Induction, Thyroid Hormones, and Oxidative Stress
Differential Effects of Two Lots of Aroclor 1254 on Enzyme Induction, Thyroid Hormones, and Oxidative Stress Open
Aroclor 1254 is a commercial mixture of polychlorinated biphenyls (PCBs), which is defined as being 54% chlorine by weight. However, the congener composition varies from lot to lot. Two lots which have been used in toxicity studies, 124-19…
View article: Accumulation of M1dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons
Accumulation of M1dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons Open
Oxidative DNA damage is one of the key events thought to be involved in mutation and cancer. The present study examined the accumulation of M1dG, 3-(2′-deoxy-β-D-erythro-pentofuranosyl)-pyrimido[1,2-a]-purin-10(3H)-one, DNA adducts after s…