Deborah McCahon
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View article: Optimising polypharmacy management in primary care through general practitioner−pharmacist collaboration, informatics, and enhancing clinician engagement: the IMPPP cluster-randomised trial
Optimising polypharmacy management in primary care through general practitioner−pharmacist collaboration, informatics, and enhancing clinician engagement: the IMPPP cluster-randomised trial Open
National Institute for Health and Care Research.
View article: Understanding structured medication reviews delivered by clinical pharmacists in primary care in England: a national cross-sectional survey
Understanding structured medication reviews delivered by clinical pharmacists in primary care in England: a national cross-sectional survey Open
Objectives This study explored how Structured Medication Reviews (SMRs) are being undertaken and the challenges to their successful implementation and sustainability. Design A cross-sectional mixed methods online survey. Setting Primary ca…
View article: Exploring the implementation and integration of structured medication reviews in primary care: A qualitative evaluation using normalization process theory
Exploring the implementation and integration of structured medication reviews in primary care: A qualitative evaluation using normalization process theory Open
Background Structured Medication Reviews (SMRs) were introduced into primary care in England for patients living with multiple long-term conditions (MLTCs), polypharmacy, increased frailty, in care homes or at risk of medicines-related har…
View article: Impact of structured medication reviews on prescribing in English Primary Care: a nationwide observational cohort study
Impact of structured medication reviews on prescribing in English Primary Care: a nationwide observational cohort study Open
Objectives The present study aimed to evaluate the impact of structured medication reviews (SMRs), by examining the proportion of eligible patients who received a review in the first two years of the programme, and whether SMRs were associ…
View article: Patients’ experiences of a patient-centred polypharmacy medication review intervention: a mixed-methods study
Patients’ experiences of a patient-centred polypharmacy medication review intervention: a mixed-methods study Open
Background People prescribed multiple medications need regular review to optimise medication and improve health outcomes. Although the most effective method to improve inappropriate polypharmacy remains unclear, medication reviews incorpor…
View article: Understanding perceptions of the safety of prescription medication sharing: a qualitative study with members of the public
Understanding perceptions of the safety of prescription medication sharing: a qualitative study with members of the public Open
CONTEXT: Prescription medication sharing involves giving and using of medicine(s) prescribed for someone else. It is a form of inappropriate medication use; when not taken correctly, prescription medicines can cause harm. There is limited …
View article: Collaborative discussions between GPs and pharmacists to optimise patient medication: a qualitative study within a UK primary care clinical trial
Collaborative discussions between GPs and pharmacists to optimise patient medication: a qualitative study within a UK primary care clinical trial Open
Background There has been significant investment in pharmacists working in UK general practice to improve the effective and safe use of medicines. However, evidence of how to optimise collaboration between GPs and pharmacists in the contex…
View article: Prevalence and risk factors for prescription medication sharing in the UK general population
Prevalence and risk factors for prescription medication sharing in the UK general population Open
CONTEXT: Prescribing of medicines is a major therapeutic intervention occurring largely in primary care. The inappropriate use of prescription medicines has significant resource implications for the health service and is associated with a …
View article: What are the attitudes of the English public towards prescription medication sharing?
What are the attitudes of the English public towards prescription medication sharing? Open
CONTEXT: Prescription medication sharing means giving medication prescribed for you to someone else or taking medication that has been prescribed for someone else. Prevalence rates for sharing range from 5-52%. However, there has been no r…
View article: Understanding non-recreational prescription medication-sharing behaviours: a systematic review
Understanding non-recreational prescription medication-sharing behaviours: a systematic review Open
Background Prescription medication sharing refers to the lending or borrowing of prescription medications where the recipient is someone other than the person for whom the prescription is intended. Sharing prescription medication can cause…
View article: Improving Medicines use in People with Polypharmacy in Primary Care (IMPPP): Protocol for a multicentre cluster randomised trial comparing a complex intervention for medication optimization against usual care
Improving Medicines use in People with Polypharmacy in Primary Care (IMPPP): Protocol for a multicentre cluster randomised trial comparing a complex intervention for medication optimization against usual care Open
Introduction: Polypharmacy is increasingly common, and associated with undesirable consequences. Polypharmacy management necessitates balancing therapeutic benefits and risks, and varying clinical and patient priorities. Current guidance …
View article: A multi-stakeholder approach to the co-production of the research agenda for medicines optimisation
A multi-stakeholder approach to the co-production of the research agenda for medicines optimisation Open
Background Up to 50% of medicines are not used as intended, resulting in poor health and economic outcomes. Medicines optimisation is ‘a person-centred approach to safe and effective medicines use, to ensure people obtain the best possible…
View article: A multi-stakeholder approach to the co-production of the research agenda for medicines optimisation
A multi-stakeholder approach to the co-production of the research agenda for medicines optimisation Open
Background Up to 50% of medicines are not used as intended, resulting in poor health and economic outcomes. Medicines optimisation is ‘a person-centred approach to safe and effective medicines use, to ensure people obtain the best possible…
View article: Prevention and treatment of venous thromboembolism in hospital and the community: a research programme including the ExACT RCT
Prevention and treatment of venous thromboembolism in hospital and the community: a research programme including the ExACT RCT Open
Background Deep-vein thrombosis and pulmonary embolism, collectively known as venous thromboembolism when clots are formed in the venous circulation, are common disorders that are often unprovoked (i.e. there is no obvious reason for the c…
View article: Barriers and enablers to collaborative working between GPs and pharmacists: a qualitative interview study
Barriers and enablers to collaborative working between GPs and pharmacists: a qualitative interview study Open
Background Many UK GP practices now employ a practice pharmacist, but little is known about how GPs and pharmacists work together to optimise medications for complex patients with multimorbidity. Aim To explore GP and pharmacist perspectiv…
View article: Subclinical thyroid dysfunction symptoms in older adults: cross-sectional study in UK primary care
Subclinical thyroid dysfunction symptoms in older adults: cross-sectional study in UK primary care Open
Background Subclinical thyroid dysfunction — abnormal serum thyrotrophin (thyroid-stimulating hormone; TSH) concentrations with normal free thyroxine (FT4) is common in older people. It remains unclear whether individuals with subclinical …
View article: A multi-stakeholder approach to the co-production of the research agenda for medicines optimisation
A multi-stakeholder approach to the co-production of the research agenda for medicines optimisation Open
Background Over one billion prescription items are dispensed in the United Kingdom annually. Up to 50% of medicines are not used as intended, resulting in sub-optimal health outcomes and harm. Medicines optimisation is ‘a person-centred ap…
View article: Efficiency versus thoroughness in medication review: a qualitative interview study in UK primary care
Efficiency versus thoroughness in medication review: a qualitative interview study in UK primary care Open
Background Medication reviews may improve the safety of prescribing and the National Institute for Health and Care Excellence (NICE) highlights the importance of involving patients in this process. Aim To explore GP and pharmacist perspect…
View article: Stability of thyroid function in older adults: the Birmingham Elderly Thyroid Study
Stability of thyroid function in older adults: the Birmingham Elderly Thyroid Study Open
Background Thyroid function tests (TFTs) are among the most requested tests internationally. However, testing practice is inconsistent, and potentially suboptimal and overly costly. The natural history of thyroid function remains poorly un…
View article: Primary care REFerral for EchocaRdiogram (REFER) in heart failure: a diagnostic accuracy study
Primary care REFerral for EchocaRdiogram (REFER) in heart failure: a diagnostic accuracy study Open
Background Symptoms of breathlessness, fatigue, and ankle swelling are common in general practice but deciding which patients are likely to have heart failure is challenging. Aim To evaluate the performance of a clinical decision rule (CDR…