Debra Meyer
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View article: The synthesis and investigation of novel 3-benzoylbenzofurans and pyrazole derivatives for anti-HIV activity
The synthesis and investigation of novel 3-benzoylbenzofurans and pyrazole derivatives for anti-HIV activity Open
The emergence of drug-resistant viruses continues to be an obstacle to effectively controlling the HIV/AIDS pandemic.
View article: The activity of Aloe arborescens Miller varieties on wound-associated pathogens, wound healing and growth factor production
The activity of Aloe arborescens Miller varieties on wound-associated pathogens, wound healing and growth factor production Open
Various Aloe L. species have been used worldwide to soothe and treat dermal wounds and burns. However, there is a lack of substantiative research on the efficacy of Aloe L. species for wound healing. The aim of this study was to investigat…
View article: Mupirocin Promotes Wound Healing by Stimulating Growth Factor Production and Proliferation of Human Keratinocytes
Mupirocin Promotes Wound Healing by Stimulating Growth Factor Production and Proliferation of Human Keratinocytes Open
Mupirocin has been reported for its role in the treatment of infected wounds through its antibacterial activity, however the role of mupirocin in promoting wound healing via alternative mechanisms has not been extensively evaluated. This s…
View article: Evaluation of Wound Healing and Antibacterial Potential of Greyia radlkoferi Szyszyl. Ethanolic Leaf Extract
Evaluation of Wound Healing and Antibacterial Potential of Greyia radlkoferi Szyszyl. Ethanolic Leaf Extract Open
Angiogenesis is an essential mechanism in both physiological and pathological functions, such as wound healing and cancer metastasis. Several growth factors mediate angiogenesis, including vascular endothelial growth factor (VEGF) and plat…
View article: Potential of succulents for eczema-associated symptoms
Potential of succulents for eczema-associated symptoms Open
Eczema is considered a worldwide concern as more people, particularly children, are affected each year. Side effects of eczema include hyperpigmentation and wrinkle formation. Due to the overexpression of interleukin (IL)-1β and IL-6, larg…
View article: CCDC 2014990: Experimental Crystal Structure Determination
CCDC 2014990: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1895247: Experimental Crystal Structure Determination
CCDC 1895247: Experimental Crystal Structure Determination Open
View article: CCDC 1892482: Experimental Crystal Structure Determination
CCDC 1892482: Experimental Crystal Structure Determination Open
View article: CCDC 1892492: Experimental Crystal Structure Determination
CCDC 1892492: Experimental Crystal Structure Determination Open
View article: Early and Mid-Career Teachers' Blog Conversations About Teacher Leadership: Issues and Insights
Early and Mid-Career Teachers' Blog Conversations About Teacher Leadership: Issues and Insights Open
Issues & InsightsGoals.One research goal was to identify shared understandings of and issues in teacher leadership by analyzing teacher blogs in a graduate teacher leadership course.A second goal was to add teacher voices to the teacher le…
View article: The potential of Clausena anisata (Willd.) Hook.f. ex Benth against Propionibacterium acnes
The potential of Clausena anisata (Willd.) Hook.f. ex Benth against Propionibacterium acnes Open
Acne vulgaris (AV) or acne is characterised as a chronic inflammatory disorder affecting the pilosebaceous unit (sebaceous gland associated with hair follicle) where the causative microorganism Propionibacterium acnes has been identified. …
View article: In vitro antimicrobial activity of extracts of some plant species used in the management of HIV/AIDS in Tanzania
In vitro antimicrobial activity of extracts of some plant species used in the management of HIV/AIDS in Tanzania Open
Six plants species (Harungana madagascariensis, Sapium ellipticum, Teclea nobilis, Pseudospondias microcarpa, Rauvolfia vomitoria and Psorospermum febrifugum) which are used in managing HIV/AIDS in Bukoba, Tanzania were screened for their …
View article: Biological Activities of Heteropyxis natalensis Against Micro-Organisms Involved in Oral Infections
Biological Activities of Heteropyxis natalensis Against Micro-Organisms Involved in Oral Infections Open
The use of complementary and alternative medicine from plants in South Africa, as in the rest of the world, continues to increase. Heteropyxis natalensis, known as the Lavender tree, is indigenous to South Africa and is traditionall…
View article: Anti-HIV Activity of Ocimum labiatum Extract and Isolated Pheophytin-a
Anti-HIV Activity of Ocimum labiatum Extract and Isolated Pheophytin-a Open
Ocimum plants are traditionally used to manage HIV/AIDS in various African countries. The effects of Ocimum labiatum extract on HIV-1 protease (PR) and reverse transcriptase (RT) is presented here along with characterization of an identifi…
View article: Triterpenoids from Ocimum labiatum Activates Latent HIV-1 Expression In Vitro: Potential for Use in Adjuvant Therapy
Triterpenoids from Ocimum labiatum Activates Latent HIV-1 Expression In Vitro: Potential for Use in Adjuvant Therapy Open
Latent HIV reservoirs in infected individuals prevent current treatment from eradicating infection. Treatment strategies against latency involve adjuvants for viral reactivation which exposes viral particles to antiretroviral drugs. In thi…
View article: Comparative Investigation of Techniques Used for Mtr Homology Model Refinement
Comparative Investigation of Techniques Used for Mtr Homology Model Refinement Open
Mtr homology model requires structural refinement to erroneous regions that are not aligned correctly to the template. In this study, refinement methods: LM, MDS, 3Drefine, GalaxyRefine and FG-MD were compared. Errat plot showed a gradual …
View article: In vitro and In vivo antimycobacterial, hepatoprotective and immunomodulatory activity of Euclea natalensis and its mode of action
In vitro and In vivo antimycobacterial, hepatoprotective and immunomodulatory activity of Euclea natalensis and its mode of action Open
View article: CCDC 1432416: Experimental Crystal Structure Determination
CCDC 1432416: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Erratum to: Curdlan-conjugated PLGA Nanoparticles possess macrophage stimulant activity and drug delivery capabilities
Erratum to: Curdlan-conjugated PLGA Nanoparticles possess macrophage stimulant activity and drug delivery capabilities Open
View article: Antioxidant and anti-inflammatory activity of Ocimum labiatum extract and isolated labdane diterpenoid
Antioxidant and anti-inflammatory activity of Ocimum labiatum extract and isolated labdane diterpenoid Open