Deeksha Misri
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View article: Abnormal Lipid Metabolism and Altered Neuronal Support by Astrocytes Lacking <i>Akap11</i> , a Risk Gene for Schizophrenia and Bipolar Disorder
Abnormal Lipid Metabolism and Altered Neuronal Support by Astrocytes Lacking <i>Akap11</i> , a Risk Gene for Schizophrenia and Bipolar Disorder Open
A-Kinase Anchoring Protein 11 ( AKAP11 ) is a shared genetic risk factor for schizophrenia and bipolar disorder, yet its role in the brain remains poorly understood. Through multi-omic analysis of Akap11 mutant mouse brains and cultured as…
View article: Muti-omics characterization reveals brain-wide disruption of synapses and region- and age-specific changes in neurons and glia in<i>Sp4</i>mutant mice, a genetic model of schizophrenia and bipolar disorder
Muti-omics characterization reveals brain-wide disruption of synapses and region- and age-specific changes in neurons and glia in<i>Sp4</i>mutant mice, a genetic model of schizophrenia and bipolar disorder Open
Schizophrenia and bipolar disorder are highly heritable mental illnesses with unclear pathophysiology. Heterozygous loss-of-function mutations of Sp4 , a zinc-finger transcription factor, greatly increase risk of schizophrenia and bipolar …
View article: Gene expression response under thermal stress in two Hawaiian corals is dominated by ploidy and genotype
Gene expression response under thermal stress in two Hawaiian corals is dominated by ploidy and genotype Open
Transcriptome data are frequently used to investigate coral bleaching; however, the factors controlling gene expression in natural populations of these species are poorly understood. We studied two corals, Montipora capitata and Pocillopor…
View article: Differential Gene Expression Analysis and Gene Ontology in Triploid and Diploid Pocillopora Acuta
Differential Gene Expression Analysis and Gene Ontology in Triploid and Diploid Pocillopora Acuta Open
Corals are marine invertebrates that are facing life-threatening environmental stressors due to climate change. Polyploidy can, in such cases, be an important source of variation and adaptation in corals and other species. Polyploidy is th…