2023-03-31
Data from Female Immunity Protects from Cutaneous Squamous Cell Carcinoma
2023-03-31 • Timothy Budden, Caroline Gaudy‐Marqueste, Sarah Craig, Yuan Hu, Charles H. Earnshaw, Shilpa Gurung, Amelle Ra, Victoria Akhras, Patrick Shenjere, R...
<div>AbstractPurpose:<p>Cancer susceptibility and mortality are higher in males, and the mutational and transcriptomic landscape of cancer differs by sex. The current assumption is that men are at higher risk of epithelial cancers as they expose more to carcinogens and accumulate more damage than women. We present data showing women present with less aggressive primary cutaneous squamous cell carcinoma (cSCC) and early strong immune activation.</p>Experimental Design:<p>We explored clinical…