Explanipedia

A Dosimetric Comparison of Coplanar Versus Noncoplanar Volumetric Modulated Arc Therapy (VMAT) for High Grade Glioma Open

Sagar Raut, Rajesh Pasricha, Manoj Gupta, Deepa Joseph, Sweety Gupta , et al. · 2025

This study highlights equal PTV coverage, homogeneity, and conformity indices between cVMAT and NcVMAT plans. A better dosimetric profile of the optic chiasma, cochlea, and equal MU per fraction favors the NcVMAT technique for treating hig…

Comparison of Quality of Life in Postoperative High-Grade Glioma Patients Treated Using EORTC and RTOG Target Delineation Techniques for Postoperative Radiotherapy Open

Shreyosi Mandal, Deepa Joseph, Ajay S Krishnan, Pragya Singh, Rajnish Kumar Arora , et al. · 2025

High-grade gliomas (HGGs) have dismal prognosis even with multimodality treatment entailing surgery, radiotherapy, and chemotherapy. Hence, assessment of improvement in quality of life (QOL) for evaluating treatment is critical. Target del…

Analysis of clinicopathological factors associated with recurrence after post operative radiotherapy in oral cavity squamous cell carcinoma Open

Jyoti Singh, Sweety Gupta, Sanjay Sajeevan, Debanjan Sikdar, Abhishek Chakravarty , et al. · 2025

Introduction: Surgery is the primary course of treatment for most patients with oral cavity tumors; however, adjuvant radiation is advised to increase the likelihood of locoregional cancer control in the presence of adverse risk factors su…

Neuroendocrine carcinoma of left adnexa: A case report of rare histology in female gynecological tract Open

Shrutikant Bhatia, Mayank Soni, Roshini Balu, Sweety Gupta, Deepa Joseph , et al. · 2025

The treatment of primary neuroendocrine neoplasms (NENs) of the female genital tract is difficult since they are rare, aggressive, have a high recurrence rate, and have poor prognosis. As no established guidelines exist, diagnosing and tre…

Prospective evaluation of impact of adaptive radiotherapy on quality of life in patients with locally advanced head and neck cancers Open

Atokali Chophy, Sweety Gupta, Yamini Bachheti, Debanjan Sikdar, Dhiraj Gupta , et al. · 2024

Assessment of Volumetric Changes Using Megavoltage-Cone Beam Computed Tomography (MV-CBCT) for Adaptive Radiotherapy in Head and Neck Cancer: A Case Series Open

Atokali Chophy, Sweety Gupta, Deepa Joseph, Swati Verma, Manoj Gupta · 2024

Dual Malignancies in Geriatric Cancer Patients: A Radiation Oncologist’s Perspective of Clinical Care Open

Yamini Bachheti, Sweety Gupta, Abhishek Chakravarty, Atokali Chophy, Deepika Raina , et al. · 2024

Background: Data pertaining to dual malignancies in the geriatric population are not only sparse but also heterogeneous. The present study evaluated the pattern of care for geriatric dual malignancy patients at a tertiary care center. Mate…

Review of Two Cases of Borderline Phyllodes Tumor of the Breast with Metastasis Open

Adil Ahmed Khan, Shivam Kumar, Zahed Ali, Dhiraj Gupta, Sanjay Sajeevan , et al. · 2024

The case series outlines two cases of borderline phyllodes tumor which later on transformed into malignant phyllodes with metastasis. Malignant phyllodes tumors, although rare, exhibit unique clinicopathological features that necessitate p…

MV CBCT based assessment of setup uncertainties and planning target volume margin in head and neck cancer Open

Debanjan Sikdar, Ajay S Krishnan, Namitha RS, Abhishek Chakravarty, Dhiraj Gupta , et al. · 2024

An isometric PTV margin of 5 mm may be considered safe if daily imaging is not being done. In case daily online pretreatment imaging is being utilized, further reduction of PTV margin is possible.

A Prospective Randomized Study of Sequential Boost vs Simultaneous Integrated Boost Intensity-Modulated Radiation Therapy with Concurrent Chemotherapy in Locally Advanced Head and Neck Cancer Open

Debanjan Sikdar, Deepa Joseph, Nidhi Sharma, Sagar N Rout, Rachit Ahuja , et al. · 2024

Background: In modern radiotherapy era of Intensity Modulated Radiotherapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT), boost of locally advanced head and neck cancer (LAHNC) can be delivered as a sequential or simultaneous integrat…

Comparison of Clinicopathological Characteristics of Patients with Early and Late-onset Colorectal Adenocarcinoma: A Cross-sectional Study Open

Bodhisattva Bose, Sunil Kumar Singh, H Sunil, Amit Gupta, Deepak Sundriyal , et al. · 2024

Introduction: Colorectal Cancer (CRC) has been primarily considered a disease of the elderly, but recent data have shown an alarming rise among young people. It has also been suggested that young age is associated with aggressive histopath…

Pattern of Occurrence and Management of Dual Malignancy: Our Institutional Experience Open

Pragya Singh, Atokali Chophy, Aviral Rastogi, Debanjan Sikdar, Sweety Gupta , et al. · 2023

Background: Management of dual malignancies is challenging in the present scenario of advanced techniques and increased life expectancy. Objectives: To determine the demographic and clinical profile of patients with dual malignancies and t…

Primary Intracranial Extraskeletal Mesenchymal Chondrosarcoma of the Brain in a Pediatric Patient: A Case Report and Review of Literature Open

Debanjan Sikdar, Sweety Gupta, Ravi Roshan, Shruti Agarwal, Deepa Joseph , et al. · 2023

Intracranial extraskeletal mesenchymal chondrosarcoma, which is characterized by undifferentiated mesenchymal cells in the presence of occasional pockets of mature hyaline cartilage, is rare in our clinical practice and commonly seen in yo…

Managing unpredictable challenge of a metastatic nodule in radiation treatment field—a case report Open

Debanjan Sikdar, Sweety Gupta, Abhishek Charavarty, Bhoomika Kaushik, Deepa Joseph , et al. · 2023

Background Despite the high prevalence of locally advanced head and neck cancer, treatment failure in the form of a cutaneous deposit in the treatment field during radiation is not common. There has never been a cytology-proven published c…

Treatment Outcomes and Survival in Hypercalcemia of Malignancy: A Grave Metabolic Emergency Open

Sweety Gupta, Aviral Rastogi, Pragya Singh, Atokali Chophy, Ravi Roushan , et al. · 2023

Cardiotoxicity in breast cancer treatment: Causes and mitigation Open

Deepthi Valiyaveettil, Deepa Joseph, Monica Malik · 2023

Survivorship issues and treatment related toxicities have considerably increased in breast cancer patients following improved therapeutic options. Cardiotoxicity has been a major treatment related side effects in these patients. Despite th…

Analysis of prognostic factors in patients with brain metastases affecting survival Open

Sweety Gupta, Sumit Kumar Singh, Atokali Chophy, Sharanya Nair, Rachit Ahuja , et al. · 2022

Introduction Brain metastases (BM) are associated with dismal prognosis as they cause significant morbidity and affect the quality of life of patients. Management of BM depends on the following factors: age, patient performance, size and t…

Varied Clinical Presentation and Management of Calvarial Metastases Open

Sweety Gupta, Gaurav Sharma, Sanjay Sajeevan, Sagar Raut, Rachit Ahuja , et al. · 2022

Calvarium and skull base can be affected by a variety of benign, tumor-like, and malignant processes. Skull metastases (SMs) may be located in any layer of the skull and may be incidental or present with neurological symptoms during the di…

Catastrophic expenditure and treatment attrition in patients seeking comprehensive colorectal cancer treatment in India: A prospective multicentre study Open

Bodhisattva Bose, Joanne Clarke, James Glasbey, Parvez David Haque, Kate Jolly , et al. · 2022

This research was funded by the National Institute for Health Research (NIHR) (NIHR 16.136.79) using UK aid from the UK Government to support global health research, by the India Institute of the University of Birmingham and by the Global …

Reconstruction with Extracorporeal Radiated Bone in a Primary Malignant Bone Tumour, A Doable Option Open

Anil Regmi, Mohit Dhingra, Deepa Joseph · 2022

Audit of In-Hospital Mortality from a Medical Oncology and Hemato-Oncology Center with the Emphasis on Best Supportive Care Open

Deepak Sundriyal, Uttam Kumar Nath, Parmod Kumar, Sweety Gupta, Deepa Joseph , et al. · 2022

Background and Objectives The newly established medical oncology and hemato-oncology center at the All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India, provided us an opportunity to audit in-hospital mortalities …

A Prospective Randomized Study of Intensity-Modulated Radiation Therapy Versus Three-Dimensional Conformal Radiation Therapy With Concurrent Chemotherapy in Locally Advanced Carcinoma Cervix Open

Nidhi Sharma, Manoj Gupta, Deepa Joseph, Sweety Gupta, Rajesh Pasricha , et al. · 2022

IMRT is associated with decreased acute hematological toxicity compared to 3DCRT with similar local control. Long-term follow-up is needed to assess any difference in long-term toxicity and survival between the two arms.

Stage Migration in Head-and-Neck Cancers due to Extranodal Extension Open

Deepa Joseph, Laxman Pandey, Rajesh Pasricha, Sagar Raut, Yanpothung Yanthan , et al. · 2022

Background: Extranodal extension (ENE) has been included as a factor for the staging of head-and-neck cancer (HNC) considering its prognostic value. Aim: The present study aimed to find out the percentage of patients with HNC getting upsta…

Chemoradiation with Weekly Paclitaxel and Carboplatin in Esophageal Squamous Cell Carcinoma: A Prospective Study Open

Deepa Joseph, Monica Irukulla Malik, Jyothi Jonnadula, Fayaz Ahmed, Deepthi Valiyaveettil · 2021

Objective Neoadjuvant chemoradiation (CRT) using paclitaxel and carboplatin has significantly improved the survival rates in carcinoma esophagus, especially in squamous cell carcinoma (SCC). This regimen has not been adequately explored pr…

Impact of COVID-19 on cancer care in India: a cohort study Open

Priya Ranganathan, Manju Sengar, Girish Chinnaswamy, Gaurav Agrawal, Rajkumar Arumugham , et al. · 2021

Use of complementary and alternative medicine among patients with cancer in a sub-Himalayan state in India: An exploratory study Open

Laxman Pandey, Rajesh Pasricha, Deepa Joseph, Rachit Ahuja, Yanpothung Yanthan , et al. · 2021

Using CAM benefitted a significant number of patients with cancer. However, there is an urgent need to integrate CAM with modern system of medicine.

Impact of COVID-19 on Cancer Care in India Open

Priya Ranganathan, Manju Sengar, Girish Chinnaswamy, Gaurav Agrawal, Rajkumar Arumugham , et al. · 2021

Socioeconomic factors affecting trastuzumab usage in patients with breast cancer in a resource constrained setting in North India Open

Pragya Singh, Rajesh Pasricha, Laxman Pandey, Deepa Joseph, Ajas Ibrahim , et al. · 2020

Background: Trastuzumab is now the standard of care in patients with Her-2 positive breast cancer. Despite its availability, high cost of treatment of trastuzumab makes it out of reach for many patients. This study analyses access to trast…

“A prospective study of assessment of neurocognitive function in illiterate patients with gliomas treated with chemoradiation” Open

Deepthi Valiyaveettil, G Ashalatha, Monica Malik, Prathyusha Eaga, Syed Fayaz Ahmed , et al. · 2020

Optimizing e-learning in oncology during the COVID-19 pandemic and beyond Open

Monica Malik, Deepthi Valiyaveettil, Deepa Joseph · 2020

The coronavirus disease 2019 (COVID-19) pandemic has profoundly impacted cancer care, research and residency training in oncology worldwide. Many countries canceled exams, shortened their residency program and medical school tenure. Tradit…

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