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RNA Interference Screening Reveals Host CaMK4 as a Regulator of Cryptococcal Uptake and Pathogenesis Open

Deepa Srikanta, Camaron R. Hole, Matthew A. Williams, Shabaana A. Khader, Tamara L. Doering · 2017

Cryptococcus neoformans , the causative agent of cryptococcosis, is an opportunistic fungal pathogen that kills over 200,000 individuals annually. This yeast may grow freely in body fluids, but it also flourishes within host cells. Despite…

Computational Analysis Reveals a Key Regulator of Cryptococcal Virulence and Determinant of Host Response Open

Stacey R. Gish, Ezekiel J. Maier, Brian C. Haynes, Felipe H. Santiago‐Tirado, Deepa Srikanta , et al. · 2016

Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills over 600,000 people annually. Here, we report integrated computational and experimental investigations of the role and mechanisms of transcriptional regulati…