Deepak Khandelwal
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View article: Development and Implementation of a Nationwide Structured Education Programme for Type 1 Diabetes in India: The T1DE Initiative
Development and Implementation of a Nationwide Structured Education Programme for Type 1 Diabetes in India: The T1DE Initiative Open
Introduction: Structured education is an integral part of type 1 diabetes (T1D) care. In India, while several programmes exist for type 2 diabetes, structured educational initiatives for people with T1D (PwT1D) and key stakeholders are lac…
View article: Functional and radiological outcomes of Essex-Lopresti procedure in intra-articular calcaneal fractures: a prospective study
Functional and radiological outcomes of Essex-Lopresti procedure in intra-articular calcaneal fractures: a prospective study Open
Background: Calcaneal fractures are among the most common tarsal bone injuries, often leading to significant morbidity. The Essex-Lopresti procedure is a minimally invasive surgical technique used to treat intra-articular fractures of the …
View article: Innovative endocrown restoration in a situs inversus totalis patient using CAD/CAM technology
Innovative endocrown restoration in a situs inversus totalis patient using CAD/CAM technology Open
Situs inversus totalis (SIT) is a rare congenital abnormality characterized by a mirror-image transposition of both the abdominal and the thoracic organs. Frequency of situs inversus is 1:10,000 and is more frequent in males: 1.5:1. SIT is…
View article: Silver-modified atraumatic restorative technique approach to dental and craniofacial care in Apert syndrome: a case-based perspective
Silver-modified atraumatic restorative technique approach to dental and craniofacial care in Apert syndrome: a case-based perspective Open
Apert syndrome is a rare congenital disorder first noted by Wheaton in 1894 and more precisely described by Eugene Apert in 1906. It is primarily characterized by craniosynostosis, midfacial hypoplasia, and complex syndactyly of the hands …
View article: A prospective comparative study of distal tibia and fibula fractures treated with tibial interlocking nailing with and without fibular plating
A prospective comparative study of distal tibia and fibula fractures treated with tibial interlocking nailing with and without fibular plating Open
Background: Distal both bone leg fractures present significant challenges in orthopedic surgery. The purpose of this study was to evaluate the functional and radiological outcomes of tibial interlocking nailing alone versus interlocking na…
View article: A Rare Case of Pyknodysostosis (Toulouse-Lautrec Syndrome): Dental Perspectives on Comprehensive Management
A Rare Case of Pyknodysostosis (Toulouse-Lautrec Syndrome): Dental Perspectives on Comprehensive Management Open
Pyknodysostosis (PKND), also referred to as Toulouse-Lautrec Syndrome, is a rare autosomal recessive disorder marked by short limbs, short stature, and generalized bone sclerosis. The hallmark signs of this disorder include sclerosis of th…
View article: Nosocomial Oral Myiasis Caused by Chrysomya bezziana in a Pediatric Patient: A Case Report with Literature Review
Nosocomial Oral Myiasis Caused by Chrysomya bezziana in a Pediatric Patient: A Case Report with Literature Review Open
Myiasis is a universal term for extreme infection by the parasitic fly larvae that feed on their host living/dead tissue. Oral myiasis is a disease in humans associated with poor oral hygiene, suppurative oral lesions, alcoholism, and seni…
View article: Overhauling dental implications in a child with rare craniofrontonasal syndrome: a case report
Overhauling dental implications in a child with rare craniofrontonasal syndrome: a case report Open
Craniofrontonasal syndrome is an extremely rare X-linked dominant genetic disorder characterized by features such as hypertelorism, craniosynostosis, ocular anomalies, a bifid nasal tip, and longitudinal ridging with splitting of the nails…
View article: Geriatric Goalposts: Of Independence And Interdependence
Geriatric Goalposts: Of Independence And Interdependence Open
Our elder population has a unique set of needs and necessities, challenges and concerns. This reflects in the approach of geriatric medicine, which aims to ensure functional freedom and independence, as well as healthy ageing, of older cit…
View article: Topical Esmolol Hydrochloride as a Novel Treatment Modality for Diabetic Foot Ulcers
Topical Esmolol Hydrochloride as a Novel Treatment Modality for Diabetic Foot Ulcers Open
Importance Preclinical and phase 1/2 studies with esmolol hydrochloride suggest its potential role in treatment of diabetic foot ulcers (DFUs). Objective To study the efficacy of topical esmolol for healing of uninfected DFUs. Design, Sett…
View article: Effects of a Lifestyle Intervention to Prevent Deterioration in Glycemic Status Among South Asian Women With Recent Gestational Diabetes
Effects of a Lifestyle Intervention to Prevent Deterioration in Glycemic Status Among South Asian Women With Recent Gestational Diabetes Open
Clinical Trials Registry of India Identifier: CTRI/2017/06/008744; Sri Lanka Clinical Trials Registry Identifier: SLCTR/2017/001; and ClinicalTrials.gov Identifier: NCT03305939.
View article: Predictors of quality of life in people living with type-1 and type-2 diabetes: An Indian perspective study and systematic review
Predictors of quality of life in people living with type-1 and type-2 diabetes: An Indian perspective study and systematic review Open
Background: This study evaluated predictors of good quality of life (QOL) in people with type-1 diabetes (T1DM) and type-2 diabetes (T2DM) using validated general health questionnaire [World Health Organization’s (WHO)-QOL-Brief (BREF) que…
View article: Clinical practice recommendations for the detection and management of hyperglycemia in pregnancy from South Asia, Africa and Mexico during COVID-19 pandemic
Clinical practice recommendations for the detection and management of hyperglycemia in pregnancy from South Asia, Africa and Mexico during COVID-19 pandemic Open
The human coronavirus disease 2019 (COVID-19) pandemic has affected overall healthcare delivery, including prenatal, antenatal and postnatal care. Hyperglycemia in pregnancy (HIP) is the most common medical condition encountered during pre…
View article: Expert opinion on the preoperative medical optimization of adults with diabetes undergoing metabolic surgery
Expert opinion on the preoperative medical optimization of adults with diabetes undergoing metabolic surgery Open
Diabetes mellitus (DM) and obesity are interrelated in a complex manner, and their coexistence predisposes patients to a plethora of medical problems. Metabolic surgery has evolved as a promising therapeutic option for both conditions. It …
View article: Real-world experience of treatment individualization based on fixed-dose combination of gliclazide extended release+ metformin extended release in type 2 diabetes mellitus
Real-world experience of treatment individualization based on fixed-dose combination of gliclazide extended release+ metformin extended release in type 2 diabetes mellitus Open
Objective To evaluate efficacy of gliclazide extended release (XR) 60 mg + metformin XR 500 mg fixed-dose combination (FDC) with metformin as add-on (as needed) in real-world clinical practice. Methods This prospective observational study …
View article: Efficacy and Safety of the Novel Dipeptidyl Peptidase-4 Inhibitor Gemigliptin in the Management of Type 2 Diabetes: A Meta-Analysis
Efficacy and Safety of the Novel Dipeptidyl Peptidase-4 Inhibitor Gemigliptin in the Management of Type 2 Diabetes: A Meta-Analysis Open
Background: No meta-analysis has holistically analysed and summarised the efficacy and safety of gemigliptin in type 2 diabetes. The meta-analysis addresses this knowledge gap.Methods: Electronic databases were searched for randomised cont…
View article: Thyroid Dysfunction and Dysmetabolic Syndrome: The Need for Enhanced Thyrovigilance Strategies
Thyroid Dysfunction and Dysmetabolic Syndrome: The Need for Enhanced Thyrovigilance Strategies Open
Thyroid dysfunction (TD) is common in metabolic disorders such as diabetes mellitus (DM), cardiovascular disease (CVD), obesity, dyslipidemia, hyperuricemia, kidney and liver dysfunctions, and polycystic ovary syndrome (PCOS). Subclinical …
View article: Glycaemic and weight-loss outcomes of graded doses of canagliflozin in type 2 diabetes — a real-world study
Glycaemic and weight-loss outcomes of graded doses of canagliflozin in type 2 diabetes — a real-world study Open
Background. Costs are the most important cause of therapeutic non-compliance. Half canagliflozin (CANA)–300 tablet has lowest cost/mg among all CANA preparations; data are unavailable on efficacy of half CANA-300. This study evaluated weig…
View article: Utility of Precision Medicine in the Management of Diabetes: Expert Opinion from an International Panel
Utility of Precision Medicine in the Management of Diabetes: Expert Opinion from an International Panel Open
Precision medicine opens new vistas for the effective use of SUs in unexpected patient populations, such as those with genetic mutations.
View article: Resource husbandry in challenging times
Resource husbandry in challenging times Open
Coronavirus disease 2019 (COVID-19) pandemic has put a huge pressure on healthcare systems across the globe, more so in developing countries. Not only patients of acute febrile illness and respiratory problems but also patients with other …
View article: Dietary Practices During Common Religious Fasts in People with Type 2 Diabetes Mellitus Among Different Religions in North India—A Questionnaire-based Study
Dietary Practices During Common Religious Fasts in People with Type 2 Diabetes Mellitus Among Different Religions in North India—A Questionnaire-based Study Open
View article: Clinical Practice Patterns of Polycystic Ovary Syndrome Among Doctors of Different Specialties—An Indian Perspective
Clinical Practice Patterns of Polycystic Ovary Syndrome Among Doctors of Different Specialties—An Indian Perspective Open
View article: The Interplay Between Pituitary Health and Diabetes Mellitus – The Need for ‘Hypophyseo-vigilance’
The Interplay Between Pituitary Health and Diabetes Mellitus – The Need for ‘Hypophyseo-vigilance’ Open
View article: Fixed-dose combination in management of type 2 diabetes mellitus: Expert opinion from an international panel
Fixed-dose combination in management of type 2 diabetes mellitus: Expert opinion from an international panel Open
Type 2 diabetes mellitus (T2DM) is a progressive disease with multifactorial etiology. The first-line therapy includes monotherapy (with metformin), which often fails to provide effective glycemic control, necessitating the addition of add…
View article: Intrathyroidal parathyroid adenoma: A perplexing entity
Intrathyroidal parathyroid adenoma: A perplexing entity Open
Intrathyroidal parathyroid adenoma (IPA) can be a cause of failed cervical exploration for primary hyperparathyroidism (PHPT). There is a lot of controversy regarding the correct approach and extent of exploration in such cases. Herein, we…