Deepak Kumar Semwal
YOU?
Author Swipe
View article: Glycyrrhizin (Glycyrrhizic Acid)—Pharmacological Applications and Associated Molecular Mechanisms
Glycyrrhizin (Glycyrrhizic Acid)—Pharmacological Applications and Associated Molecular Mechanisms Open
Background/Objectives: Natural products, especially plant metabolites, play a crucial role in drug development and are widely used in medicine, cosmetics, and nutrition. The present review aims to provide a comprehensive overview of the ph…
View article: Phytochemical, ethnomedicinal, and pharmacological perspectives of Asparagus curillus (Buch.-Ham.) ex Roxb.
Phytochemical, ethnomedicinal, and pharmacological perspectives of Asparagus curillus (Buch.-Ham.) ex Roxb. Open
Plants have been used in traditional medicine systems worldwide, including Ayurveda, Traditional Chinese medicine, and Unani medicine. In India, plants have been utilized for medicinal purposes for centuries and form an integral part of Ay…
View article: Anticonvulsant activity of Rudraksha (Elaeocarpus angustifolius Blume) bark against picrotoxin-induced convulsions in rats
Anticonvulsant activity of Rudraksha (Elaeocarpus angustifolius Blume) bark against picrotoxin-induced convulsions in rats Open
Epilepsy is a neurological condition characterized by recurrent electrical activity in the brain's temporal lobe. It is a chronic disorder marked by an imbalance between excitatory and inhibitory neurotransmitters, resulting in uncontrolle…
View article: Withania somnifera a journey from traditionalrejuvenator to anti-SARS-CoV-2 remedy
Withania somnifera a journey from traditionalrejuvenator to anti-SARS-CoV-2 remedy Open
Ashwagandha (Withania somnifera L. Dunal) roots have been used in Ayurveda for fever, asthma, arthritis,rheumatism, inflammation, tuberculosis, mental diseases, and male sexual disorders. Phytochemical studiesrevealed that the plant mainly…
View article: Ayurveda and its concept of dietetics (Pathya ahaar kalpana) – a potential approach to healthy gut Microbiota
Ayurveda and its concept of dietetics (Pathya ahaar kalpana) – a potential approach to healthy gut Microbiota Open
The present article deals with the general history of Ayurveda and its concept of dietetics for healthy microbiota. Ayurveda is an ancient science of life which has been practiced in India for the past thousands of years. In addition to th…
View article: Evaluation of antidiabetic effect of Cissampelos pareira L. (Menispermaceae) root extract in streptozotocin-nicotinamide-induced diabetic rats via targeting SGLT2 inhibition
Evaluation of antidiabetic effect of Cissampelos pareira L. (Menispermaceae) root extract in streptozotocin-nicotinamide-induced diabetic rats via targeting SGLT2 inhibition Open
Background: Cissampelos pareira L. (Menispermaceae) has been used in Indian traditional medicine for a variety of human ailments including diabetes mellitus. Although its anti-hyperglycemic activity has been validated by previous studies, …
View article: Anti-diarrheal Activity of the Aqueous Extract of Stem Bark of <i>Myrica nagi</i> in Albino Rats
Anti-diarrheal Activity of the Aqueous Extract of Stem Bark of <i>Myrica nagi</i> in Albino Rats Open
Background and objectivesMyrica nagi Thunb., belonging to the family Myricaceae, is used in Indian traditional medicine to treat diarrhea. This study aimed to assess the anti-diarrheal activity of the aqueous extract of stem bark of Myrica…
View article: Modulation of gut microbiota with Ayurveda diet and lifestyle
Modulation of gut microbiota with Ayurveda diet and lifestyle Open
Background: The prevalence of type 2 diabetes (T2D) has increased substantially in the past few decades throughout the world. In India, the epidemic of diabetes continues to increase irrespective of area, status, and age. Despite various s…
View article: Formulation and evaluation of SGLT2 inhibitory effect of a polyherbal mixture inspired from Ayurvedic system of medicine
Formulation and evaluation of SGLT2 inhibitory effect of a polyherbal mixture inspired from Ayurvedic system of medicine Open
The treatment with PHF (250 and 500 mg/kg) showed a significant (p < 0.05) decrease in blood glucose levels by 56.37% and 58.17%, respectively. The levels of SGOT, SGPT and bilirubin were significantly reduced in PHF-fed diabetic rats. His…
View article: Infection Pattern, Treatment Protocols and Post-COVID-19 Complications–A Survey on 706 COVID-19 Recovered Participants
Infection Pattern, Treatment Protocols and Post-COVID-19 Complications–A Survey on 706 COVID-19 Recovered Participants Open
Background and objectivesThe pandemic of coronavirus disease 2019 (COVID-19) has killed millions of people globally and has severely affected quality of life and global economy. The present randomized survey aimed to collect information ba…
View article: Ethnomedicinal knowledge on the precise use of herbal medicine - An interview-based study on traditional healers from Jaunsar-Bawar region of Uttarakhand
Ethnomedicinal knowledge on the precise use of herbal medicine - An interview-based study on traditional healers from Jaunsar-Bawar region of Uttarakhand Open
Background: Jaunsar-Bawar region of Uttarakhand is well-known for its rich biodiversity. In continuation of our previous field survey on traditional medicinal plants used in diabetes mellitus, this study was designed to gather traditional …
View article: Coronil – What is dispute if it is developed from time-tested Ayurvedic Science?
Coronil – What is dispute if it is developed from time-tested Ayurvedic Science? Open
The discussion about Coronil, a new COVID-19 herbal medicine of Patanjali Ayurved, Ltd. (Times of India, 2020) is on all over the world. Some groups are challenging its efficacy and some its process of development (Business Standard, 2020)…
View article: Antimicrobial activity of the water-soluble ash extract from the invasive weed Parthenium hysterophorus L.
Antimicrobial activity of the water-soluble ash extract from the invasive weed Parthenium hysterophorus L. Open
Parthenium hysterophorus L., also known as congress grass or carrot grass, is a widely distributed invasive weed which is a big challenge for sustainable agriculture. For the past several years, a number of attempts have been made to evalu…
View article: Natural Molecules Having Anti-SARS-CoV Activity – Cannot They Be Effective Against SARS-CoV-2?
Natural Molecules Having Anti-SARS-CoV Activity – Cannot They Be Effective Against SARS-CoV-2? Open
In the current scenario, developing treatments, identifying cures and formulating intervention strategies to fight against the COVID-19 outbreak, have become the major concern for researchers globally. Several studies have confirmed the mo…
View article: Antioxidant and anti-inflammatory activities of selected medicinal herbs and their polyherbal formulation
Antioxidant and anti-inflammatory activities of selected medicinal herbs and their polyherbal formulation Open
The medicinal plants possessing antioxidant and anti-inflammatory properties are used since ancient times for curing several healthcare issues. The present study was done for evaluation of anti-oxidant and anti-inflammatory activities of B…
View article: Formulation and Evaluation of Polyherbal Cream and Lotion for the Treatment of Psoriasis-Induced Secondary Infections
Formulation and Evaluation of Polyherbal Cream and Lotion for the Treatment of Psoriasis-Induced Secondary Infections Open
Background: Psoriasis is one of the most common skin diseases in humans and affects a major population worldwide. The aim of the present study is to evaluate the efficacy of selected polyherbal formulations against psoriasis-induced second…
View article: Drimia indica: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses
Drimia indica: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses Open
Drimia indica (Roxb.) Jessop (Asparagaceae) is a reputed Ayurvedic medicine for a number of therapeutic benefits, including for cardiac diseases, indigestion, asthma, dropsy, rheumatism, leprosy, and skin ailments. The present work aimed t…
View article: Ethnomedicinal Investigation of Medicinal Plants of Chakrata Region (Uttarakhand) Used in the Traditional Medicine for Diabetes by Jaunsari Tribe
Ethnomedicinal Investigation of Medicinal Plants of Chakrata Region (Uttarakhand) Used in the Traditional Medicine for Diabetes by Jaunsari Tribe Open
The Himalayan region is the treasure house of natural wealth, particularly of medicinal and aromatic plants. These plants are used by the Indian traditional healers for the past many centuries to treat various ailments such as skin disorde…
View article: Effect of pH on optimization of photofermentative hydrogen production by co-culture of Rhodobacter sphaeroides-NMBL-02 and Bacillus firmus-NMBL-03
Effect of pH on optimization of photofermentative hydrogen production by co-culture of Rhodobacter sphaeroides-NMBL-02 and Bacillus firmus-NMBL-03 Open
Rhodobacter sphaeroides NMBL-02, photosynthetic purple non sulfur (PNS) bacteria and associated Bacillus firmus NMBL-03 were isolated from water sample collected from 15-20 inches beneath the surface of ponds from Northern region of India …
View article: Combination of mTOR and MAPK Inhibitors—A Potential Way to Treat Renal Cell Carcinoma
Combination of mTOR and MAPK Inhibitors—A Potential Way to Treat Renal Cell Carcinoma Open
Renal cell carcinoma (RCC) is the most common neoplasm that occurs in the kidney and is marked by a unique biology, with a long history of poor response to conventional cancer treatments. In the past few years, there have been significant …
View article: Treatment of Type 2 Diabetes with Ayurveda: A Case Report
Treatment of Type 2 Diabetes with Ayurveda: A Case Report Open
Background: A 32-year-old woman having earlier history of hyperthyroidism was diagnosed with type 2 diabetes with a random sugar level of 449 mg dLG 1 .Methodology: The doctor prescribed metformin HCl (1000 mg) with vildagliptin (50 mg) tw…
View article: Myricetin: A Dietary Molecule with Diverse Biological Activities
Myricetin: A Dietary Molecule with Diverse Biological Activities Open
Myricetin is a common plant-derived flavonoid and is well recognised for its nutraceuticals value. It is one of the key ingredients of various foods and beverages. The compound exhibits a wide range of activities that include strong anti-o…
View article: Discovery of Natural SGLT2-Inhibitors for Type 2 Diabetes – Possible Way to Reduce Side Effects
Discovery of Natural SGLT2-Inhibitors for Type 2 Diabetes – Possible Way to Reduce Side Effects Open
The number of patients diagnosed with diabetes mellitus in all over the world has risen ominously in the past few decades, in which majority of cases belongs to type 2 diabetes. Previously, type 2 diabetes was known as adult-onset and noni…
View article: Adverse Health Effects of Tobacco and Role of Ayurveda in their Reduction
Adverse Health Effects of Tobacco and Role of Ayurveda in their Reduction Open
Tobacco in all forms is dangerous for human health and caused various diseases such as heart attacks, hypertension, strokes, pulmonary disease and cancer.Smoking is a leading cause of lung cancer whereas mouth cancer is mainly caused by ch…
View article: Antiplasmodial activity of aqueous extract of<i>Berberis aristata</i>roots against<i>Plasmodium berghei</i>-infected BALB/c mice
Antiplasmodial activity of aqueous extract of<i>Berberis aristata</i>roots against<i>Plasmodium berghei</i>-infected BALB/c mice Open
These results provide relevant scientific evidences for the traditional medicinal use of this plant as malaria remedy and further advocates the isolation and characterization of active antiplasmodial principle from this plant.
View article: Ayurvedic research and methodology: Present status and future strategies
Ayurvedic research and methodology: Present status and future strategies Open
Ayurveda is a science of life with a holistic approach to health and personalized medicine. It is one of the oldest medical systems, which comprises thousands of medical concepts and hypothesis. Interestingly, Ayurveda has ability to treat…