Deepak Langade
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Efficacy and Safety of Vildagliptin Sustained-Release and Metformin Sustained-Release Fixed-Dose Combination in Indian Patients With Type 2 Diabetes Mellitus: A Real-World Perspective Open
Introduction The efficacy of vildagliptin as an add-on to metformin has been demonstrated in type 2 diabetes mellitus (T2DM) patients inadequately controlled on metformin monotherapy, as well as in early combination therapy for newly diagn…
Effect of Liners on Pulpal Outcome After Partial Caries Removal in Permanent Teeth: A Systematic Review and Meta-Analysis Open
Partial caries removal reduces the risk of pulp exposure while preserving the tooth structure that is otherwise unnecessarily lost during the cavity preparation. Liners are applied on the dentinal floors to induce the formation of tertiary…
Efficacy and safety of ashwagandha root extract on sexual health in healthy women: findings of a prospective, randomized, double-blind, placebo-controlled study Open
Objective This study compared the efficacy and safety of Ashwagandha Root Extract (ARE) in healthy women against a placebo for improvement of Female Sexual Dysfunction (FSD).Method In this randomized, double-blind, placebo-controlled study…
The Vital Role of Materiovigilance in Orthopedic Practice Open
Introduction In the evolving landscape of modern medicine, the role of medical devices is becoming increasingly central, especially in orthopedic surgery. From implants and prosthetics to advanced diagnostic tools, orthopedic surgeons rely…
View article: Exploring Pleasure and Risks: The Interplay Between Recreational Substances and Sexual Health
Exploring Pleasure and Risks: The Interplay Between Recreational Substances and Sexual Health Open
Sexual pleasure holds significant importance for individuals, relationships and societies due to its physiological, psychological and social dimensions. It is an individual experience that can signify or represent one or many aspects of pe…
Elevating Orthopaedic Care through Materiovigilance Open
Advanced medical devices serve an important role in modern medicine, particularly in orthopaedics, by improving patients’ mobility and quality of life. However, the intricacy of devices such as joint replacements and spine implants raises …
Evaluation of the Anxiolytic and Antidepressant Effects of Standardized Ashwagandha (<i>Withania somnifera</i>) Root Extract in Wistar Rats Open
Ashwagandha (Withania somnifera) is a popular herb in Ayurveda, the traditional medicine system in India. It is known to exert stress-mitigating properties and has been extensively studied for its safety and efficacy in various disorders. …
Efficacy and safety of Ashwagandha Root Extract on Sexual Health in Healthy Women: Findings of a Prospective, Randomized, Double-Blind, Placebo-Controlled Study Open
Background: Ashwagandha is an herbal extract known for its potential benefits on various aspects of human health, including stress reduction and hormone regulation. Objective: This prospective, randomized, double-blind, placebo-controlled …
Efficacy and Safety of Eight-Week Therapy with Ashwagandha Root Extract in Improvement of Sexual Health in Healthy Men: Findings of a Prospective, Randomized, Double-Blind, Placebo-Controlled Study Open
Ashwagandha, a traditional Indian Ayurvedic remedy, an adaptogen, may improve sexual dysfunction in men and women. This 8-week prospective, double-blind, randomized, placebo-controlled study evaluated the efficacy and safety of Ashwagandha…
Analysis of usage pattern of glutathione by dermatologists: Results of a cross-sectional study Open
Glutathione is one of the non-enzymatic antioxidants that is also involved in regulation of cellular proliferation and apoptosis. The application of Glutathione for skin lightening and depigmentation in dermatology started after discovery …
Effect of Right Nostril Breathing on Cardiorespiratory Parameters and Reaction Time in Young, Healthy Humans: An Interventional Study Open
Background and Objective: Yogic breathing helps in reduction of stress and strain in the body. Right and left nostril breathings (RNB and LNB, respectively) have different effects on cardiorespiratory parameters. The study was performed to…
Assessment of Knowledge, Attitude, and Practice Toward Materiovigilance Among the Health Care Workers in Mumbai: A Questionnaire-Based Study Open
Introduction: Materiovigilance is an organized method for locating, obtaining, recording, and evaluating any unfavorable occurrences associated with medical devices to protect a patient’s health by preventing recurrences. Recent advancemen…
Role of Eight-Week Therapy with Ashwagandha Root Extract in Improving Sexual Health in Healthy Men: Findings of a Prospective, Randomized, Double-Blind, Placebo-Controlled Study Open
Ashwagandha, a traditional Indian Ayurvedic remedy, an adaptogen, can improve sexual dysfunction in men and women. This 8-week prospective, double-blind, randomized, placebo-controlled study evaluated the efficacy and safety of Ashwagandha…
One‐year outcomes after prostate artery embolization versus laser enucleation: A network meta‐analysis Open
Background Although holmium laser enucleation (HoLEP) is considered a size‐independent procedure for treatment of an enlarged prostate, prostate artery embolization (PAE) is emerging as an alternative modality to treat moderate and large b…
Third National Pharmacovigilance Week (2023) at D Y Patil University School of Medicine, Navi Mumbai, Maharashtra, India Open
Background Pharmacovigilance (PV) in India has a long history. After its start in 1986, India joined the World Health Organization (WHO) Programme for International Drug Monitoring in 1998. The National Programme of Pharmacovigilance intro…
Comparison of postoperative pain using two instrumentation techniques followed by laser irradiation in nonvital teeth with symptomatic apical periodontitis: A double-blind randomized controlled trial Open
Aim: Postoperative pain can be caused due to apical extrusion of debris following chemomechanical preparation. This study aimed to compare mechanized reciprocating stainless steel files and continuous rotary instrumentation with laser irra…
Association of Adverse Events Following Immunisation with COVID-19 Vaccine and Lifestyle of Individuals: A Cross-sectional Analytical Survey Open
Introduction: The Coronavirus Disease-2019 (COVID-19) pandemic, being an emerging world health issue, has led to the swift development of vaccines. Various lifestyles, health conditions, and behaviours affect the body’s reaction to immunis…
Adverse drug reactions reporting: Five years analysis from a teaching hospital Open
A BSTRACT Background: Adverse drug reactions (ADRs) are important cause of morbidity and mortality. Despite its known importance, rate and quality (completeness score) of ADR reporting is not satisfactory. The objective of this study was t…
A retrospective cross-sectional study assessing adverse events following immunization (AEFI) of COVID 19 vaccine in a subset of Indian population Open
As the COVID-19 pandemic is an emerging healthcare concern, there has been swift vaccine development with minimal clinical trials questioning its protective efficacy outside of clinical trial conditions. The study aims to analyze the adver…
Postpartum Use of Shavari Bar® Improves Breast Milk Output: A Double-Blind, Prospective, Randomized, Controlled Clinical Study Open
Background and objectives Appropriate nutrition, along with the establishment of lactation, is of paramount importance for the feeding mother and the growing neonate. Asparagus racemosus, a common name for Shatavari, is a well-known herb t…
Evaluation of the Effect of Left Nostril Breathing on Cardiorespiratory Parameters and Reaction Time in Young Healthy Individuals Open
Left nostril breathing is associated with a decrease in cardiovascular parameters and an increase in VC and PEFR. This technique may be useful for putting up a fight against the stress and strain of daily life. This simple exercise may als…
Comparative evaluation of postoperative pain following chemomechanical preparation of single-rooted nonvital teeth with symptomatic apical periodontitis with and without laser irradiation: A double-blind randomized placebo controlled clinical trial Open
Laser irradiation following chemomechanical preparation led to significant reduction in postoperative pain and can be considered as a valuable adjunct.
Efficacy of Cilnidipine (L/N-type Calcium Channel Blocker) in Treatment of Hypertension: A Meta-Analysis of Randomized and Non-randomized Controlled Trials Open
Cilnidipine has similar anti-hypertensive effects compared with other first-line antihypertensive drugs commonly used in practice. We recommend Cilnidipine as a novel first-line CCB for the management of hypertension either as a monotherap…