Deepta Ghate
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View article: Lens survival after tube shunt surgery: Risk factors impacting time to cataract extraction following glaucoma drainage implant surgery
Lens survival after tube shunt surgery: Risk factors impacting time to cataract extraction following glaucoma drainage implant surgery Open
Purpose: To determine the lens survival time following glaucoma drainage implant (GDI) surgery and identify the risk factors that may predict the time to cataract surgery. Design: Retrospective cross-sectional study. Methods: Phakic patien…
View article: Impact of social determinants of health and medication burden on quality of life and disease severity in glaucoma
Impact of social determinants of health and medication burden on quality of life and disease severity in glaucoma Open
View article: Peripheral visual information is necessary for visually-guided navigation
Peripheral visual information is necessary for visually-guided navigation Open
View article: Pragmatic adjunctive usage of netarsudil: A retrospective chart review from a tertiary care center
Pragmatic adjunctive usage of netarsudil: A retrospective chart review from a tertiary care center Open
Purpose: This retrospective chart review of netarsudil (Rhopressa) characterizes intra-ocular pressure (IOP) reduction, drug tolerance, drug cost, and compliance in a tertiary university Midwest clinic in a variety of glaucoma diagnoses on…
View article: Effects of Acute Intracranial Pressure Changes on Optic Nerve Head Morphology in Humans and Pig Model
Effects of Acute Intracranial Pressure Changes on Optic Nerve Head Morphology in Humans and Pig Model Open
We conclude that ONH does not show measurable morphological changes in response to acute changes of CSFP/ICP. Proposed mechanisms include compensatory and opposing changes in IOP and CSFP/ICP and nonlinear or nonmonotonic effects of IOP an…
View article: A Hydrogel Ionic Circuit Based High‐Intensity Iontophoresis Device for Intraocular Macromolecule and Nanoparticle Delivery
A Hydrogel Ionic Circuit Based High‐Intensity Iontophoresis Device for Intraocular Macromolecule and Nanoparticle Delivery Open
Iontophoresis is an electrical‐current‐based, noninvasive drug‐delivery technology, which is particularly suitable for intraocular drug delivery. Current ocular iontophoresis devices use low current intensities that significantly limit mac…
View article: Pragmatic usage of Netarsudil: A retrospective chart review from a tertiary care center
Pragmatic usage of Netarsudil: A retrospective chart review from a tertiary care center Open
View article: Visual field loss and on-road driving performance in glaucoma
Visual field loss and on-road driving performance in glaucoma Open
View article: Current methods and new approaches to assess aqueous humor dynamics
Current methods and new approaches to assess aqueous humor dynamics Open
Introduction: Aqueous humor and its dynamics (AHD) serve numerous functions to sustain ocular health and clear vision. Current methods to assess AHD have led to improved understanding of ocular physiology, pathologies caused by abnormal in…
View article: Three-dimensional shape analysis of peripapillary retinal pigment epithelium-basement membrane layer based on OCT radial images
Three-dimensional shape analysis of peripapillary retinal pigment epithelium-basement membrane layer based on OCT radial images Open
The peripapillary retinal pigment epithelium-basement membrane (ppRPE/BM) layer angle was recently proposed as a potential index for estimating intracranial pressure noninvasively. However, the ppRPE/BM layer angle, measured from the optic…
View article: What do patients with glaucoma see: a novel iPad app to improve glaucoma patient awareness of visual field loss
What do patients with glaucoma see: a novel iPad app to improve glaucoma patient awareness of visual field loss Open
Purpose Glaucoma patients with peripheral vision loss have in the past subjectively described their field loss as ‘blurred’ or ‘no vision compromise’. We developed an iPad app for patients to self-characterise perception within areas of gl…
View article: Glaucomatous visual fields and neurocognitive function are independently associated with poor lane maintenance during driving simulation
Glaucomatous visual fields and neurocognitive function are independently associated with poor lane maintenance during driving simulation Open
Background Driving simulators are a safe alternative to on-road vehicles for studying driving behavior in glaucoma drivers. Visual field (VF) loss severity is associated with higher driving simulator crash risk, though mechanisms explainin…
View article: Effect of a Schlemm’s Canal Microstent on Postoperative Intraocular Pressure Elevation after Cataract Surgery
Effect of a Schlemm’s Canal Microstent on Postoperative Intraocular Pressure Elevation after Cataract Surgery Open
View article: Predictors of Intraocular Pressure Lowering after Phacoemulsification and iStent Implantation
Predictors of Intraocular Pressure Lowering after Phacoemulsification and iStent Implantation Open
View article: The Effects of Acute Intracranial Pressure Changes on the Episcleral Venous Pressure, Retinal Vein Diameter and Intraocular Pressure in a Pig Model
The Effects of Acute Intracranial Pressure Changes on the Episcleral Venous Pressure, Retinal Vein Diameter and Intraocular Pressure in a Pig Model Open
We believe that the ophthalmic effects of acute ICP elevation are mediated by increased intracranial venous pressure producing upstream pressure changes within the orbital and retinal veins. These results offer exciting possibilities for t…
View article: Pseudo-glaucomatous cupping and impaired visual processing in cerebral palsy
Pseudo-glaucomatous cupping and impaired visual processing in cerebral palsy Open
View article: Pictorializing what people with glaucoma perceive in regions of visual field loss: Results from a novel iPad app
Pictorializing what people with glaucoma perceive in regions of visual field loss: Results from a novel iPad app Open
View article: Three-Dimensional Characterization of Peripapillary Retinal Pigment Epithelium-Basement Membrane Layer in Patients following Lumbar Puncture
Three-Dimensional Characterization of Peripapillary Retinal Pigment Epithelium-Basement Membrane Layer in Patients following Lumbar Puncture Open
Purpose: To develop and test an innovative semi-automatic method for quantifying the three-dimensional morphology of the peripapillary retinal pigment epithelium-basement membrane (ppRPE/BM) layer, with application to lumbar puncture (LP) …
View article: Effect of Near Work on Intraocular Pressure in Emmetropes
Effect of Near Work on Intraocular Pressure in Emmetropes Open
Objective . To determine whether accommodation induced by reading alters intraocular pressure (IOP) in healthy, young, emmetropic adults and to document the duration and magnitude of this effect. Design . Cross-sectional study. Participant…
View article: Early-Stage Ocular Hypertension Alters Retinal Ganglion Cell Synaptic Transmission in the Visual Thalamus
Early-Stage Ocular Hypertension Alters Retinal Ganglion Cell Synaptic Transmission in the Visual Thalamus Open
Axonopathy is a hallmark of many neurodegenerative diseases including glaucoma, where elevated intraocular pressure (ocular hypertension, OHT) stresses retinal ganglion cell (RGC) axons as they exit the eye and form the optic nerve. OHT ca…
View article: Ocular hypertension alters spiking behavior of neurons in the visual thalamus.
Ocular hypertension alters spiking behavior of neurons in the visual thalamus. Open
View article: Mapping Visual Fields in a Panoramic Driving Simulator Under Different Task Loads in Patients with Glaucoma
Mapping Visual Fields in a Panoramic Driving Simulator Under Different Task Loads in Patients with Glaucoma Open
Glaucoma causes visual field loss, which may impair detection of objects and hazards during driving. Standard clinical visual field testing, developed to address status of disease, is not designed to capture the effects of visual field los…
View article: Spatially Biased Eye Movements in Older Drivers with Glaucoma and Visual Field Defects
Spatially Biased Eye Movements in Older Drivers with Glaucoma and Visual Field Defects Open
Patients with glaucoma are at greater driving safety risk due to visual field defects. These driving safety risks may be mitigated by compensatory eye movements. We measured spatial allocation of eye movements in a panoramic driving simula…
View article: Early-Stage Ocular Hypertension Alters Retinal Ganglion Cell Synaptic Transmission in the Visual Thalamus
Early-Stage Ocular Hypertension Alters Retinal Ganglion Cell Synaptic Transmission in the Visual Thalamus Open
Axonopathy is a hallmark of many neurodegenerative diseases including glaucoma, where elevated intraocular pressure (ocular hypertension, OHT) stresses retinal ganglion cell (RGC) axons as they exit the eye and form the optic nerve. OHT ca…
View article: Relative Contributions of Intracranial Pressure and Intraocular Pressure on Lamina Cribrosa Behavior
Relative Contributions of Intracranial Pressure and Intraocular Pressure on Lamina Cribrosa Behavior Open
Purpose . To characterize the relative contributions of intraocular pressure (IOP) and intracranial pressure (ICP) on lamina cribrosa (LC) behavior, specifically LC depth (LCD) and LC peak strain. Methods . An axially symmetric finite elem…
View article: Mapping glaucomatous visual fields during panoramic driving simulation
Mapping glaucomatous visual fields during panoramic driving simulation Open
Glaucoma is an optic neuropathy that impairs peripheral vision, increasing motor vehicle crash risk. Mechanisms underlying impaired driving in glaucoma demand further study. Here, we developed a novel driving simulator visual field (DSVF) …
View article: Effect of Race on Clinical Outcomes in Combined Phacoemulsification-iStent® Compared to Phacoemulsification Alone
Effect of Race on Clinical Outcomes in Combined Phacoemulsification-iStent® Compared to Phacoemulsification Alone Open
View article: Effect of systemic comorbidities on clinical outcomes after trabecular micro-bypass stent with cataract extraction and cataract extraction alone
Effect of systemic comorbidities on clinical outcomes after trabecular micro-bypass stent with cataract extraction and cataract extraction alone Open
View article: Trends in Ophthalmic Drug Prices Based on Drug Acquisition Cost from 2013-2017
Trends in Ophthalmic Drug Prices Based on Drug Acquisition Cost from 2013-2017 Open
View article: Episcleral Venous Pressure And Intraocular Pressure As Biomarkers For Intracranial Pressure Changes
Episcleral Venous Pressure And Intraocular Pressure As Biomarkers For Intracranial Pressure Changes Open