Deirdre McClean
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View article: Weakly interacting species as drivers of ecological stability
Weakly interacting species as drivers of ecological stability Open
Determining how individual species can act to moderate the stability of entire ecosystems is a pressing challenge in a world undergoing rapid environmental change. Here, we show that even very weakly interacting species with no discernible…
View article: Water‐level fluctuations and nutrient enrichment interact to alter ecosystem structure in distinct ways at different water depths
Water‐level fluctuations and nutrient enrichment interact to alter ecosystem structure in distinct ways at different water depths Open
Aquatic ecosystems are often impacted by several human‐derived pressures simultaneously. A key challenge for ecologists is to develop mechanistic understanding of the cumulative effects of multiple stressors on freshwater biodiversity. We …
View article: Population genomics of Escherichia coli in livestock-keeping households across a rapidly developing urban landscape
Population genomics of Escherichia coli in livestock-keeping households across a rapidly developing urban landscape Open
Quantitative evidence for the risk of zoonoses and the spread of antimicrobial resistance remains lacking. Here, as part of the UrbanZoo project, we sampled Escherichia coli from humans, livestock and peri-domestic wildlife in 99 household…
View article: Landscape genomics of Escherichia coli in livestock-keeping households across a rapidly developing urban city
Landscape genomics of Escherichia coli in livestock-keeping households across a rapidly developing urban city Open
The keeping of livestock has been posited as a risk factor for the emergence of zoonoses and the spread of antimicrobial resistance. However, quantitative evidence regarding the major sources of pathogenic and drug-resistant bacteria and t…
Inferring the distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii Open
Spontaneous mutations are the source of new genetic variation and are thus central to the evolutionary process. In molecular evolution and quantitative genetics, the nature of genetic variation depends critically on the distribution of eff…
View article: Coping with multiple enemies: pairwise interactions do not predict evolutionary change in complex multitrophic communities
Coping with multiple enemies: pairwise interactions do not predict evolutionary change in complex multitrophic communities Open
Predicting the ecological and evolutionary trajectories of populations in multispecies communities is one of the fundamental challenges in ecology. Many of these predictions are made by scaling patterns observed from pairwise interactions.…
View article: Direct inference of the distribution of fitness effects of spontaneous mutations in<i>Chlamydomonas reinhardtii</i>
Direct inference of the distribution of fitness effects of spontaneous mutations in<i>Chlamydomonas reinhardtii</i> Open
Spontaneous mutations are the source of new genetic variation and are thus central to the evolutionary process. In molecular evolution and quantitative genetics, the nature of genetic variation depends critically on the distribution of fit…
View article: Focussing on resistance to front-line drugs is the most effective way to combat the antimicrobial resistance crisis
Focussing on resistance to front-line drugs is the most effective way to combat the antimicrobial resistance crisis Open
In medical, scientific and political arenas relating to antimicrobial resistance (AMR) there is currently an intense focus on multi-drug resistant pathogens that render last-line antimicrobial treatments ineffective. We question the curren…
View article: Single gene locus changes perturb complex microbial communities as much as apex predator loss
Single gene locus changes perturb complex microbial communities as much as apex predator loss Open
Many bacterial species are highly social, adaptively shaping their local environment through the production of secreted molecules. This can, in turn, alter interaction strengths among species and modify community composition. However, the …