Dai Cheng
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View article: PricingLogic: Evaluating LLMs Reasoning on Complex Tourism Pricing Tasks
PricingLogic: Evaluating LLMs Reasoning on Complex Tourism Pricing Tasks Open
We present PricingLogic, the first benchmark that probes whether Large Language Models(LLMs) can reliably automate tourism-related prices when multiple, overlapping fare rules apply. Travel agencies are eager to offload this error-prone ta…
View article: Prognostic factors and nomogram for intracranial malignant meningeal sarcomatosis: a population-based retrospective surveillance, epidemiology, and end results database analysis
Prognostic factors and nomogram for intracranial malignant meningeal sarcomatosis: a population-based retrospective surveillance, epidemiology, and end results database analysis Open
This SEER study identifies important prognostic factors for malignant MS. While suggesting benefits of comprehensive treatment, the findings are limited by sample size and require validation in larger, prospective multicenter studies.
View article: Pharmacologic inhibition of CSF-1R suppresses intrinsic tumor cell growth in osteosarcoma with CSF-1R overexpression
Pharmacologic inhibition of CSF-1R suppresses intrinsic tumor cell growth in osteosarcoma with CSF-1R overexpression Open
These findings conclusively demonstrated that pharmacological inhibition of CSF-1R activity by ABSK021 resulted in significant anti-tumor effects in preclinical osteosarcoma models with CSF-1R overexpression. The high prevalence of CSF-1R …
View article: Monitoring of the lateral spread response combined with brainstem auditory evoked potentials in microvascular decompression for hemifacial spasm
Monitoring of the lateral spread response combined with brainstem auditory evoked potentials in microvascular decompression for hemifacial spasm Open
Objective Despite high cure rates, symptom persistence and auditory dysfunction occur sometimes after microvascular decompression (MVD) surgery for hemifacial spasm (HFS). This study evaluated whether combined intraoperative monitoring of …
View article: High-throughput RNA and Single-cell RNA Sequencing to Identify Sepsis associated Molecular Mechanisms and the Blood Immune Cell Landscape
High-throughput RNA and Single-cell RNA Sequencing to Identify Sepsis associated Molecular Mechanisms and the Blood Immune Cell Landscape Open
Sepsis, a leading cause of death in intensive care units (ICUs), is a complex systemic inflammatory response to infection with high morbidity and mortality. Its pathogenesis involves dysregulated inflammation, immune dysfunction, and metab…
View article: Characteristic components from Rehmannia radix and their effects on insulin resistance through PI-3K/AKT signaling pathway in HepG2 Cells
Characteristic components from Rehmannia radix and their effects on insulin resistance through PI-3K/AKT signaling pathway in HepG2 Cells Open
Rehmannia radix is a kind of food and medicinal material, riched in monoterpenoids, phenylethanol glycosides, triterpenes, flavonoids, and other kinds of chemical compounds, among which monoterpenoids such as iridoids and ionones, and phen…
View article: Validation of the Mechanism of Action of TYROBP Related to Blood-Brain Barrier Function in Intracerebral Hemorrhage by Bioinformatics Analysis.
Validation of the Mechanism of Action of TYROBP Related to Blood-Brain Barrier Function in Intracerebral Hemorrhage by Bioinformatics Analysis. Open
TYROBP promotes the pathological progression of ICH by increasing the BBB permeability and facilitating microglial pyroptosis.
View article: Prognostic Factors and Nomogram for Malignant Brainstem Ependymoma: A Population‐Based Retrospective Surveillance, Epidemiology, and End Results Database Analysis
Prognostic Factors and Nomogram for Malignant Brainstem Ependymoma: A Population‐Based Retrospective Surveillance, Epidemiology, and End Results Database Analysis Open
Purpose This study aimed to identify prognostic factors and develop a nomogram for survival in patients with brainstem ependymoma. Methods Data of 652 patients diagnosed with brainstem ependymoma extracted from the Surveillance, Epidemiolo…
View article: Systemic immune inflammation index as a predictor of disease severity in tetanus patients: A retrospective observational study
Systemic immune inflammation index as a predictor of disease severity in tetanus patients: A retrospective observational study Open
Objective This study aimed to analyze the predictive value of the systemic immune inflammation index (SII) for the severity of disease in tetanus patients. Methods Clinical data of 34 tetanus patients admitted to the Second People’s Hospit…
View article: Adult supratentorial peripheral primitive neuroectodermal tumor with multiple metastases: a case report and literature review
Adult supratentorial peripheral primitive neuroectodermal tumor with multiple metastases: a case report and literature review Open
Background Intracranial primitive neuroectodermal tumors (PNETs) are characterized by poorly differentiated, highly malignant, aggressive small round tumor cells originating from the central and peripheral nervous systems. Case presentatio…
View article: Correction: Cheng et al. Dietary Chlorella vulgaris Ameliorates Altered Immunomodulatory Functions in Cyclophosphamide-Induced Immunosuppressive Mice. Nutrients 2017, 9, 708
Correction: Cheng et al. Dietary Chlorella vulgaris Ameliorates Altered Immunomodulatory Functions in Cyclophosphamide-Induced Immunosuppressive Mice. Nutrients 2017, 9, 708 Open
In the original publication [...]
View article: A Simulation of the Mechanical Testing of the Cell Membrane and Cytoskeleton
A Simulation of the Mechanical Testing of the Cell Membrane and Cytoskeleton Open
Cell models play a crucial role in analyzing the mechanical response of cells and quantifying cellular damage incurred during micromanipulation. While traditional models can capture the overall mechanical behavior of cells, they often lack…
View article: Systemic Immune Inflammation Index as a Predictor of Disease Severity in Tetanus Patients
Systemic Immune Inflammation Index as a Predictor of Disease Severity in Tetanus Patients Open
Objective This study aimed to analyze the predictive value of the systemic immune inflammation index (SII) for the severity of disease in tetanus patients. Methods Clinical data of 34 tetanus patients admitted to the Second People's Hospit…
View article: Aluminum-maltol induced oxidative stress and reduced AMPK activity via BCK-related energy supply failure in C6 cell
Aluminum-maltol induced oxidative stress and reduced AMPK activity via BCK-related energy supply failure in C6 cell Open
Aluminum (Al) exposure significantly interferes with the energy supply in astrocytes, which may be a potential mechanism of Al-induced neurotoxicity. This study was designed to explore the mechanisms of Al-induced energy supply impairment …
View article: ProSG: Using Prompt Synthetic Gradients to Alleviate Prompt Forgetting of RNN-like Language Models
ProSG: Using Prompt Synthetic Gradients to Alleviate Prompt Forgetting of RNN-like Language Models Open
RNN-like language models are getting renewed attention from NLP researchers in recent years and several models have made significant progress, which demonstrates performance comparable to traditional transformers. However, due to the recur…
View article: Adult patients with tetanus in Anhui Province of China from 2013 to 2022: A retrospective study
Adult patients with tetanus in Anhui Province of China from 2013 to 2022: A retrospective study Open
Tetanus is a highly fatal infectious disease with an incubation period of 7 to 8 days. The aim of this study was to identify risk factors for death in tetanus patients, develop a nomogram model for predicting mortality risk. This retrospec…
View article: Epicatechin attenuates lead (Pb)-induced cognitive impairment in mice: regulation on Nrf2 signaling pathway, and interference on the interaction between Pb with albumin
Epicatechin attenuates lead (Pb)-induced cognitive impairment in mice: regulation on Nrf2 signaling pathway, and interference on the interaction between Pb with albumin Open
Epicatechin (EC) was used in this study to antagonize the cognitive dysfunction caused by lead (Pb) exposure in mice. Eight-week-old male Kunming mice were treated with PbCl2 (20 mg/kg) and/or EC (50 mg/kg) by gavage administration for 4 w…
View article: Circ_0078607 increases platinum drug sensitivity via miR-196b-5p/GAS7 axis in ovarian cancer
Circ_0078607 increases platinum drug sensitivity via miR-196b-5p/GAS7 axis in ovarian cancer Open
Platinum-based chemotherapy is one of the predominant strategies for treating ovarian cancer (OC), however, platinum resistance greatly influences the therapeutic effect. Circular RNAs (circRNAs) have been found to participate in the patho…
View article: Ultrasonic Pre-treatment for the Preparation of ACE-inhibitory Peptides from the Tea Residue Protein through Enzymatic Hydrolysis and Its Stability
Ultrasonic Pre-treatment for the Preparation of ACE-inhibitory Peptides from the Tea Residue Protein through Enzymatic Hydrolysis and Its Stability Open
Angiotensin-converting enzyme (ACE) plays an important role in blood pressure regulation, and inhibition of its activity is beneficial to maintain blood pressure balance. Food-derived ACE inhibitory peptides have attracted wide attention d…
View article: Mechanical Characterization and Modelling of Subcellular Components of Oocytes
Mechanical Characterization and Modelling of Subcellular Components of Oocytes Open
The early steps of embryogenesis are controlled exclusively by the quality of oocyte that linked closely to its mechanical properties. The mechanical properties of an oocyte were commonly characterized by assuming it was homogeneous such t…
View article: Optimization of Extraction Process of Tea Protein by Mixed Reverse Microemulsion System
Optimization of Extraction Process of Tea Protein by Mixed Reverse Microemulsion System Open
Three reverse microemulsion systems were prepared using sodium bis (2-ethylhexyl) sulfosuccinate (AOT), cetyltrimethylammonium bromide (CTAB), sodium dodecyl sulfate (SDS) and Tween80, and the effects of surfactant concentration, ionic sur…
View article: Vehicle Re-Identification System Based on Appearance Features
Vehicle Re-Identification System Based on Appearance Features Open
Aiming at the low recognition accuracy caused by the problems of angle, illumination, and occlusion in vehicle re-identification based on deep learning, a vehicle re-identification method based on multibranch network feature extraction and…
View article: CADG: A Model Based on Cross Attention for Domain Generalization
CADG: A Model Based on Cross Attention for Domain Generalization Open
In Domain Generalization (DG) tasks, models are trained by using only training data from the source domains to achieve generalization on an unseen target domain, this will suffer from the distribution shift problem. So it's important to le…
View article: Creatine kinase is involved aluminum-induced energy metabolism disorder in astrocyte: Role of aluminum speciation
Creatine kinase is involved aluminum-induced energy metabolism disorder in astrocyte: Role of aluminum speciation Open
Aluminum (Al) is an important environmental neurotoxicity, and the speciation of Al largely determines the absorption and toxic effects in human body. The brain-type creatine kinase (CK-BB), which is an important kinase that regulates ener…