Delphine Payros
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View article: A Non-genotoxic Variant of Escherichia coli Nissle 1917 EcN 2.0 Overexpressing Microcins Reduces Intestinal Carriage of ST131 ESBL-Producing Escherichia coli
A Non-genotoxic Variant of Escherichia coli Nissle 1917 EcN 2.0 Overexpressing Microcins Reduces Intestinal Carriage of ST131 ESBL-Producing Escherichia coli Open
View article: New approach methodologies for risk assessment of urinary occurring toxicants
New approach methodologies for risk assessment of urinary occurring toxicants Open
View article: Genotoxic interaction between deoxynivalenol and acrylamide
Genotoxic interaction between deoxynivalenol and acrylamide Open
View article: Mycotoxins hazard: the European view
Mycotoxins hazard: the European view Open
International audience
View article: Uncovering a new family of conserved virulence factors that promote the production of host‐damaging outer membrane vesicles in Gram‐negative bacteria
Uncovering a new family of conserved virulence factors that promote the production of host‐damaging outer membrane vesicles in Gram‐negative bacteria Open
CprA is a short‐chain dehydrogenase/reductase (SDR) that contributes to resistance against colistin and antimicrobial peptides. The cprA gene is conserved across Pseudomonas aeruginosa clades and its expression is directly regulated by the…
View article: Évaluation de la toxicité des contaminants alimentaires comme les mycotoxines chez les porcs : développement et utilisation de modèles de culture d'organes ex vivo comme alternative à l'expérimentation animale.
Évaluation de la toxicité des contaminants alimentaires comme les mycotoxines chez les porcs : développement et utilisation de modèles de culture d'organes ex vivo comme alternative à l'expérimentation animale. Open
International audience
View article: Roles of Cytochromes P450 and Ribotoxicity in the Interaction between Two Preoccupying Mycotoxins, Aflatoxin B1 and Deoxynivalenol
Roles of Cytochromes P450 and Ribotoxicity in the Interaction between Two Preoccupying Mycotoxins, Aflatoxin B1 and Deoxynivalenol Open
View article: HlyF, an underestimated virulence factor of uropathogenic Escherichia coli
HlyF, an underestimated virulence factor of uropathogenic Escherichia coli Open
View article: Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli
Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli Open
The molecular factors and genetic adaptations that contributed to the emergence of Mycobacterium tuberculosis (MTB) from an environmental Mycobacterium canettii -like ancestor, remain poorly investigated. In MTB , the PhoPR two-component r…
View article: HlyF, an underestimated virulence factor of uropathogenic<i>Escherichia coli</i>
HlyF, an underestimated virulence factor of uropathogenic<i>Escherichia coli</i> Open
Urinary tract infections (UTIs) are predominantly caused by uropathogenic Escherichia coli (UPEC). By analysing a representative collection of UPEC strains from community-acquired infections, we showed that 20 % of these strains had the ab…
View article: The foodborne contaminant deoxynivalenol exacerbates DNA damage caused by a broad spectrum of genotoxic agents
The foodborne contaminant deoxynivalenol exacerbates DNA damage caused by a broad spectrum of genotoxic agents Open
View article: Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages
Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages Open
Mycobacterium tuberculosis, the main causative agent of human tuberculosis, is transmitted from person to person via small droplets containing very few bacteria. Optimizing the chance to seed in the lungs is therefore a major adaptation to…
View article: Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages
Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages Open
Mycobacterium tuberculosis , the main causative agent of human tuberculosis, is transmitted from person to person via small droplets containing very few bacteria. Optimizing the chance to seed in the lungs is therefore a major adaptation t…
View article: Dietary Exposure to the Food Contaminant Deoxynivalenol Triggers Colonic Breakdown by Activating the Mitochondrial and the Death Receptor Pathways
Dietary Exposure to the Food Contaminant Deoxynivalenol Triggers Colonic Breakdown by Activating the Mitochondrial and the Death Receptor Pathways Open
Introduction The food contamination by mycotoxins is of increasing public health concerns. Deoxynivalenol (DON), a mycotoxin contaminating cereals, has been associated with the exacerbation of inflammatory bowel diseases (IBD), thereby rai…
View article: The food contaminant, deoxynivalenol, modulates the Thelper/Treg balance and increases inflammatory bowel diseases
The food contaminant, deoxynivalenol, modulates the Thelper/Treg balance and increases inflammatory bowel diseases Open
View article: In vitro and in vivo effects of a mycotoxin, deoxynivalenol, and a trace metal, cadmium, alone or in a mixture on the intestinal barrier
In vitro and in vivo effects of a mycotoxin, deoxynivalenol, and a trace metal, cadmium, alone or in a mixture on the intestinal barrier Open
Deoxynivalenol (DON), one of the most widespread mycotoxins in Europe, and cadmium (Cd), a widespread environmental pollutant, are common food contaminants. They exert adverse effects on different organs including kidney, liver, and intest…
View article: Protein O-mannosylation deficiency increases LprG-associated lipoarabinomannan release by Mycobacterium tuberculosis and enhances the TLR2-associated inflammatory response
Protein O-mannosylation deficiency increases LprG-associated lipoarabinomannan release by Mycobacterium tuberculosis and enhances the TLR2-associated inflammatory response Open
View article: Impact of mycotoxins on the intestine: are mucus and microbiota new targets?
Impact of mycotoxins on the intestine: are mucus and microbiota new targets? Open
There is an increasing awareness of the deleterious effects attributed to mycotoxins during their fate within the gut, particularly for deoxynivalenol (DON), zearalenone (ZEN), ochratoxin A (OTA), fumonisin B1 (FB1), aflatoxin B1 (AFB1), a…
View article: The Food Contaminant Deoxynivalenol Exacerbates the Genotoxicity of Gut Microbiota
The Food Contaminant Deoxynivalenol Exacerbates the Genotoxicity of Gut Microbiota Open
An increasing number of human beings from developed countries are colonized by Escherichia coli strains producing colibactin, a genotoxin suspected to be associated with the development of colorectal cancers. Deoxynivalenol (DON) is the mo…
View article: Deoxynivalenol in the liver and lymphoid organs of rats: effects of dose and duration on immunohistological changes
Deoxynivalenol in the liver and lymphoid organs of rats: effects of dose and duration on immunohistological changes Open
Deoxynivalenol (DON) is one of the most prevalent type B trichothecenes present in food inducing adverse effects, including intestinal changes and immunosuppression. The aim of the present study was to investigate the effects of DON on rat…
View article: Oral Tolerance Failure upon Neonatal Gut Colonization with Escherichia coli Producing the Genotoxin Colibactin
Oral Tolerance Failure upon Neonatal Gut Colonization with Escherichia coli Producing the Genotoxin Colibactin Open
The intestinal barrier controls the balance between tolerance and immunity to luminal antigens. When this finely tuned equilibrium is deregulated, inflammatory disorders can occur. There is a concomitant increase, in urban populations of d…