Dengfeng Yang
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View article: SFB flagellin mediates cell adhesion, endocytosis and immune regulation in germ-free mice
SFB flagellin mediates cell adhesion, endocytosis and immune regulation in germ-free mice Open
Introduction Segmented filamentous bacteria (SFB) colonization dynamics are crucial for host immune regulation. Given this, the present study specifically examined the functions of SFB flagellin in bacterial adhesion, cellular internalizat…
View article: Recent Advances in Research on Inhibitory Effects of Seaweed Extracts Against Parasites
Recent Advances in Research on Inhibitory Effects of Seaweed Extracts Against Parasites Open
Parasitic diseases pose a serious threat to the health of humans and the steady development of livestock husbandry. Although there are certain drug-based treatment methods, with the widespread application of drugs, various parasites are gr…
View article: The Impact of Chitinase Binding Domain Truncation on the Properties of CaChi18B from Chitinilyticum aquatile CSC-1
The Impact of Chitinase Binding Domain Truncation on the Properties of CaChi18B from Chitinilyticum aquatile CSC-1 Open
The chitinase binding domain (ChBD) plays a crucial role in the properties of enzymes. To assess its impact, we cloned a truncated mutant of the chitinase gene CaChi18B from the novel chitinase-producing facultative anaerobic bacterium Chi…
View article: Analysis of immune cell activation in patients with diabetes foot ulcer from the perspective of single cell
Analysis of immune cell activation in patients with diabetes foot ulcer from the perspective of single cell Open
This study offers insights into DM and DFU cytology. T cells in DFU are activated, attacking normal tissues and worsening tissue damage. The ATP5E gene may be related to the ecological remodeling of DM, and TPP1, TLR4, and RIPK2 are potent…
View article: Antimicrobial mechanisms and antifungal activity of compounds generated by banana rhizosphere Pseudomonas aeruginosa Gxun-2 against fusarium oxysporum f. sp. cubense
Antimicrobial mechanisms and antifungal activity of compounds generated by banana rhizosphere Pseudomonas aeruginosa Gxun-2 against fusarium oxysporum f. sp. cubense Open
Introduction Fusarium wilt of banana, also recognized as Panama disease, is caused by the soil-borne fungus Fusarium oxysporum f. sp. cubense tropical race 4 (FOC TR4). In recent years, strategies utilizing biocontrol agents, comprising an…
View article: Biochemical Properties of a Novel Cold-Adapted GH19 Chitinase with Three Chitin-Binding Domains from <i>Chitinilyticum aquatile</i> CSC-1 and Its Potential in Biocontrol of Plant Pathogenic Fungi
Biochemical Properties of a Novel Cold-Adapted GH19 Chitinase with Three Chitin-Binding Domains from <i>Chitinilyticum aquatile</i> CSC-1 and Its Potential in Biocontrol of Plant Pathogenic Fungi Open
GH19 (glycoside hydrolase 19) chitinases play crucial roles in the enzymatic conversion of chitin and biocontrol of phytopathogenic fungi. Herein, a novel multifunctional chitinase of GH19 (CaChi19A), which contains three chitin-bin…
View article: Heterologous Expression and Biochemical Characterization of a Novel Lytic Polysaccharide Monooxygenase from Chitinilyticum aquatile CSC-1
Heterologous Expression and Biochemical Characterization of a Novel Lytic Polysaccharide Monooxygenase from Chitinilyticum aquatile CSC-1 Open
Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent enzymes that catalyze the oxidative cleavage of recalcitrant polysaccharides. There are limited reports on LPMOs capable of concurrently catalyzing the oxidative cleavage of …
View article: A Comparative Transcriptome Analysis Unveils the Mechanisms of Response in Feather Degradation by Pseudomonas aeruginosa Gxun-7
A Comparative Transcriptome Analysis Unveils the Mechanisms of Response in Feather Degradation by Pseudomonas aeruginosa Gxun-7 Open
Microbial degradation of feathers offers potential for bioremediation, yet the microbial response mechanisms warrant additional investigation. In prior work, Pseudomonas aeruginosa Gxun-7, which demonstrated robust degradation of feathers …
View article: Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis through m6A-modified ATF4 in autoimmune thyroid disease
Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis through m6A-modified ATF4 in autoimmune thyroid disease Open
Both environmental and genetic factors contribute to the etiology of autoimmune thyroid disease (AITD) including Graves' disease (GD) and Hashimoto's thyroiditis (HT). However, the exact pathogenesis and interactions that occur between env…
View article: The Improved para-Selective C(sp2)-H Borylation of Anisole Derivatives Enabled by Bulky Lewis Acid
The Improved para-Selective C(sp2)-H Borylation of Anisole Derivatives Enabled by Bulky Lewis Acid Open
An improved para-selective C(sp2)-H borylation of anisole derivatives is described. The selective borylation is probably dominated by the change in electron density on the aromatic ring when a Lewis acid is coordinated with an anisole subs…
View article: Structural and Physical Properties of Alginate Pretreated by High-Pressure Homogenization
Structural and Physical Properties of Alginate Pretreated by High-Pressure Homogenization Open
To develop a high-efficient extraction method, we investigated the use of high-pressure homogenization (HPH) as a novel pretreatment technology for the extraction of sodium alginate (SA) from Laminaria japonica. After the single-factor exp…
View article: A super‐high‐speed PM motor drive for centrifugal air compressor used in fuel cell unmanned aerial vehicle
A super‐high‐speed PM motor drive for centrifugal air compressor used in fuel cell unmanned aerial vehicle Open
The authors show a PM motor drive with the maximum speed of 170,000 r/min for a super‐high‐speed centrifugal air compressor, which is used in high‐altitude unmanned aerial vehicle (UAV). Conventional turbochargers used in high‐altitude UAV…
View article: Optimizing Extraction Condition and Characterization the Structural and Physical property of the Alginate Pretreated by High-pressure Homogenization
Optimizing Extraction Condition and Characterization the Structural and Physical property of the Alginate Pretreated by High-pressure Homogenization Open
In this study, we had investigated the use of high-pressure homogenization (HPH) as a novel pretreatment method for the extraction of sodium alginate (SA) from Laminaria japonica. Our results demonstrated that under optimal condition of 10…
View article: m6A methylation reader IGF2BP2 activates endothelial cells to promote angiogenesis and metastasis of lung adenocarcinoma
m6A methylation reader IGF2BP2 activates endothelial cells to promote angiogenesis and metastasis of lung adenocarcinoma Open
View article: CD69 serves as a potential diagnostic and prognostic biomarker for hepatocellular carcinoma
CD69 serves as a potential diagnostic and prognostic biomarker for hepatocellular carcinoma Open
View article: Expression and Purification of Glycosyltransferase DnmS from Streptomyces peucetius ATCC 27952 and Study on Catalytic Characterization of Its Reverse Glycosyltransferase Reaction
Expression and Purification of Glycosyltransferase DnmS from Streptomyces peucetius ATCC 27952 and Study on Catalytic Characterization of Its Reverse Glycosyltransferase Reaction Open
Anthracyclines are an important class of natural antitumor drugs. They have a conservative aromatic tetracycline backbone that is substituted with different deoxyglucoses. The deoxyglucoses are crucial for the biological activity of many b…
View article: Effect of Interstage Pipeline on the Performance of Two-Stage Centrifugal Compressors for Automotive Hydrogen Fuel Cells
Effect of Interstage Pipeline on the Performance of Two-Stage Centrifugal Compressors for Automotive Hydrogen Fuel Cells Open
At present, two-stage centrifugal compressors based on air bearing and high-speed motor technology are widely used in automotive hydrogen fuel cells. The low-pressure stage and high-pressure stage of the compressor are directly connected t…
View article: An Investigation of the Performance and Internal Flow of Variable Nozzle Turbines with Split Sliding Guide Vanes
An Investigation of the Performance and Internal Flow of Variable Nozzle Turbines with Split Sliding Guide Vanes Open
In order to effectively weaken the leakage flow and shock intensity of traditional “swing” type guide vanes in a variable nozzle turbine, a new flow control device named the “split sliding guide vane” (SSGV) is studied in the present work.…
View article: Biochemical purification and characterization of a truncated acidic, thermostable chitinase from marine fungus for N-acetylglucosamine production
Biochemical purification and characterization of a truncated acidic, thermostable chitinase from marine fungus for N-acetylglucosamine production Open
N-acetylglucosamine (GlcNAc) is widely used in nutritional supplement and is generally produced from chitin using chitinases. While most GlcNAc is produced from colloidal chitin, it is essential that chitinases be acidic enzymes. Herein, w…
View article: The Discovery, Enzymatic Characterization and Functional Analysis of a Newly Isolated Chitinase from Marine-Derived Fungus Aspergillus fumigatus df347
The Discovery, Enzymatic Characterization and Functional Analysis of a Newly Isolated Chitinase from Marine-Derived Fungus Aspergillus fumigatus df347 Open
In order to discover a broad-specificity and high stability chitinase, a marine fungus, Aspergillus fumigatus df347, was identified in the sediments of mangrove wetlands in Qinzhou Bay, China. The chitinase gene (AfChi28) from A. fumigatus…
View article: Different Chiral Ligands Assisted Enantioselective C-H Functionalization with Transition-Metal Catalysts
Different Chiral Ligands Assisted Enantioselective C-H Functionalization with Transition-Metal Catalysts Open
C–H bonds are common in organic molecules, and the functionalization of these inactive C–H bonds has become one of the most powerful methods used to assemble complicated bioactive molecules from readily available starting materials. Howeve…
View article: High-Efficiency Narrow-Band Blue Emission from Lead-Doped Cs2znbr4 Nanocrystals
High-Efficiency Narrow-Band Blue Emission from Lead-Doped Cs2znbr4 Nanocrystals Open
View article: Novel Marine Secondary Metabolites Worthy of Development as Anticancer Agents: A Review
Novel Marine Secondary Metabolites Worthy of Development as Anticancer Agents: A Review Open
Secondary metabolites from marine sources have a wide range of biological activity. Marine natural products are promising candidates for lead pharmacological compounds to treat diseases that plague humans, including cancer. Cancer is a lif…
View article: Potentials of marine natural products against malaria, leishmaniasis, and trypanosomiasis parasites: a review of recent articles
Potentials of marine natural products against malaria, leishmaniasis, and trypanosomiasis parasites: a review of recent articles Open
View article: Synthesis, Characterization, Photoluminescence, Molecular Docking and Bioactivity of Zinc (II) Compounds Based on Different Substituents
Synthesis, Characterization, Photoluminescence, Molecular Docking and Bioactivity of Zinc (II) Compounds Based on Different Substituents Open
Six new zinc(II) complexes were prepared by the reaction of ZnBr2 or ZnI2 with 4′-(substituted-phenyl)-2,2′:6′,2′′-terpyridine compounds, bearing p-methylsulfonyl (L1), p-methoxy (L2) and p-methyl (L3), which were characterized by elementa…
View article: Antibiotics Development and the Potentials of Marine-Derived Compounds to Stem the Tide of Multidrug-Resistant Pathogenic Bacteria, Fungi, and Protozoa
Antibiotics Development and the Potentials of Marine-Derived Compounds to Stem the Tide of Multidrug-Resistant Pathogenic Bacteria, Fungi, and Protozoa Open
As the search for new antibiotics continues, the resistance to known antimicrobial compounds continues to increase. Many researchers around the world, in response to antibiotics resistance, have continued to search for new antimicrobial co…
View article: Combinatorial Enzymatic Synthesis of Unnatural Long-Chain β-Branch Pyrones by a Highly Promiscuous Enzyme
Combinatorial Enzymatic Synthesis of Unnatural Long-Chain β-Branch Pyrones by a Highly Promiscuous Enzyme Open
In this study, we described in detail a combinatorial enzymatic synthesis approach to produce a series of unnatural long-chain β-branch pyrones. We attempted to investigate the catalytic potential of a highly promiscuous enzyme type III PK…
View article: Study on the Photoluminescent and Thermal Properties of Zinc Complexes with a N6O4 Macrocyclic Ligand
Study on the Photoluminescent and Thermal Properties of Zinc Complexes with a N6O4 Macrocyclic Ligand Open
Reactions between a N6O4 macrocyclic ligand (L1) and several Zn(II) salts (trifluoromethane sulfonate, p-toluenesulfonate, acetate, benzoate, o-, m- or p-hydroxybenzoate) led to the formation of seven complexes, [Zn2L1 (DMSO)4](OSO2CF3)4 (…
View article: Casing wall static pressure distribution behavior in a centrifugal compressor with asymmetric inlet/outlet structures
Casing wall static pressure distribution behavior in a centrifugal compressor with asymmetric inlet/outlet structures Open
Asymmetric structures of the bent inlet pipes and outlet volute are typically adopted in centrifugal compressors. By using asymmetric inlet/outlet structures, the uniformity of the compressor’s internal flow field in the circumferential di…
View article: Two new alkylated furan derivatives with antifungal and antibacterial activities from the plant endophytic fungus <i>Emericella</i> sp. XL029
Two new alkylated furan derivatives with antifungal and antibacterial activities from the plant endophytic fungus <i>Emericella</i> sp. XL029 Open
Two new alkylated furan derivatives, 5-(undeca-3′,5′,7′-trien-1′-yl)furan-2-ol (1) and 5-(undeca-3′,5′,7′-trien-1′-yl)furan-2-carbonate (2), were isolated from the crude extract of the plant endophytic fungus Emericella