Denis E. Corpet
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View article: Data from Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption
Data from Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption Open
Red meat is probably carcinogenic to humans (WHO/IARC class 2A), in part through heme iron-induced lipoperoxidation. Here, we investigated whether red meat promotes carcinogenesis in rodents and modulates associated biomarkers in volunteer…
View article: Supplementary documents from Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption
Supplementary documents from Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption Open
Supplementary figure, tables and results Supplementary Figure S1. Flowchart of the 6 studies Supplementary Table S1. Transitions and collision energies used for the quantification (Bold) and confirmation (Italic) of AAH on the triple quadr…
Supplementary Data from Heme Iron from Meat and Risk of Colorectal Cancer: A Meta-analysis and a Review of the Mechanisms Involved Open
Supplementary Methods, Table, and Figure
View article: Data from Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption
Data from Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption Open
Red meat is probably carcinogenic to humans (WHO/IARC class 2A), in part through heme iron-induced lipoperoxidation. Here, we investigated whether red meat promotes carcinogenesis in rodents and modulates associated biomarkers in volunteer…
Data from Heme Iron from Meat and Risk of Colorectal Cancer: A Meta-analysis and a Review of the Mechanisms Involved Open
Red meat and processed meat intake is associated with a risk of colorectal cancer, a major cause of death in affluent countries. Epidemiological and experimental evidence supports the hypothesis that heme iron present in meat promotes colo…
View article: Supplementary documents from Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption
Supplementary documents from Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption Open
Supplementary figure, tables and results Supplementary Figure S1. Flowchart of the 6 studies Supplementary Table S1. Transitions and collision energies used for the quantification (Bold) and confirmation (Italic) of AAH on the triple quadr…
Data from Heme Iron from Meat and Risk of Colorectal Cancer: A Meta-analysis and a Review of the Mechanisms Involved Open
Red meat and processed meat intake is associated with a risk of colorectal cancer, a major cause of death in affluent countries. Epidemiological and experimental evidence supports the hypothesis that heme iron present in meat promotes colo…
Supplementary Data from Heme Iron from Meat and Risk of Colorectal Cancer: A Meta-analysis and a Review of the Mechanisms Involved Open
Supplementary Methods, Table, and Figure
View article: Data from A Central Role for Heme Iron in Colon Carcinogenesis Associated with Red Meat Intake
Data from A Central Role for Heme Iron in Colon Carcinogenesis Associated with Red Meat Intake Open
Epidemiology shows that red and processed meat intake is associated with an increased risk of colorectal cancer. Heme iron, heterocyclic amines, and endogenous N-nitroso compounds (NOC) are proposed to explain this effect, but their relati…
View article: Data from A Central Role for Heme Iron in Colon Carcinogenesis Associated with Red Meat Intake
Data from A Central Role for Heme Iron in Colon Carcinogenesis Associated with Red Meat Intake Open
Epidemiology shows that red and processed meat intake is associated with an increased risk of colorectal cancer. Heme iron, heterocyclic amines, and endogenous N-nitroso compounds (NOC) are proposed to explain this effect, but their relati…
View article: Supplementary Methods, Results and Figures 1 to 5 from A Central Role for Heme Iron in Colon Carcinogenesis Associated with Red Meat Intake
Supplementary Methods, Results and Figures 1 to 5 from A Central Role for Heme Iron in Colon Carcinogenesis Associated with Red Meat Intake Open
Supplementary Methods, Results, and Figures 1 to 5. Supplementary Figure 1: Flowchart of Bastide et al. Supplementary Figure 2. The consequences of the loss of Apc function in an intestinal cellular model derived from C57BL/6J mice. Supple…
View article: Supplementary Methods, Results and Figures 1 to 5 from A Central Role for Heme Iron in Colon Carcinogenesis Associated with Red Meat Intake
Supplementary Methods, Results and Figures 1 to 5 from A Central Role for Heme Iron in Colon Carcinogenesis Associated with Red Meat Intake Open
Supplementary Methods, Results, and Figures 1 to 5. Supplementary Figure 1: Flowchart of Bastide et al. Supplementary Figure 2. The consequences of the loss of Apc function in an intestinal cellular model derived from C57BL/6J mice. Supple…
Why Does Sars-Cov-2 Survive Longer on Plastic Than on Paper? Open
The Covid-19 coronavirus, SARS-CoV-2, is inactivated much faster on paper (3h) than on plastic (7d). By classifying materials according to virus stability on their surface, the following list is obtained (from long to short stability): pol…
Re: ‘Application of the key characteristics of carcinogens in cancer hazard evaluation’: response to Goodman, Lynch and Rhomberg Open
International audience
Application of the key characteristics of carcinogens in cancer hazard identification Open
Smith et al. (Env. Health Perspect. 124: 713, 2016) identified 10 key characteristics (KCs), one or more of which are commonly exhibited by established human carcinogens. The KCs reflect the properties of a cancer-causing agent, such as 'i…
View article: Red Wine and Pomegranate Extracts Suppress Cured Meat Promotion of Colonic Mucin-Depleted Foci in Carcinogen-Induced Rats
Red Wine and Pomegranate Extracts Suppress Cured Meat Promotion of Colonic Mucin-Depleted Foci in Carcinogen-Induced Rats Open
Processed meat intake is carcinogenic to humans. We have shown that intake of a workshop-made cured meat with erythorbate promotes colon carcinogenesis in rats. We speculated that polyphenols could inhibit this effect by limitation of endo…
Model Systems of Human Intestinal Flora, to Set Acceptable Daily Intakes of Antimicrobial Residues Open
The veterinary use of antimicrobial drugs in food producing animals may result in residues in food that might modify the consumer gut ora. This review compares three model systems that maintain a complex ora of human origin: (i) human ora-…