Denis Tritsch
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View article: New Application of cycloSaligenyl Prodrugs Approach for the Delivery of Fosfoxacin Derivatives in Mycobacteria
New Application of cycloSaligenyl Prodrugs Approach for the Delivery of Fosfoxacin Derivatives in Mycobacteria Open
In this work, we implemented for the first time the cycloSaligenyl prodrug strategy to increase the bioavailability of fosmidomycin phosphate analogs in bacteria. Here, we report the synthesis of 34 cycloSaligenyl prodrugs of fosfoxacin an…
View article: α,α-Difluorophosphonohydroxamic Acid Derivatives among the Best Antibacterial Fosmidomycin Analogues
α,α-Difluorophosphonohydroxamic Acid Derivatives among the Best Antibacterial Fosmidomycin Analogues Open
Three α,α-difluorophosphonate derivatives of fosmidomycin were synthesized from diethyl 1,1-difluorobut-3-enylphosphonate and were evaluated on Escherichia coli. Two of them are among the best 1-deoxy-d-xylulose 5-phosphate reductoisomeras…
View article: The specific molecular architecture of plant 3-hydroxy-3-methylglutaryl-CoA lyase
The specific molecular architecture of plant 3-hydroxy-3-methylglutaryl-CoA lyase Open
View article: Synthesis and biological evaluation of aryl phosphoramidate prodrugs of fosfoxacin and its derivatives
Synthesis and biological evaluation of aryl phosphoramidate prodrugs of fosfoxacin and its derivatives Open
View article: Farnesol-mediated shift in the metabolic origin of prenyl groups used for protein prenylation in plants
Farnesol-mediated shift in the metabolic origin of prenyl groups used for protein prenylation in plants Open
View article: Flavonoids: True or promiscuous inhibitors of enzyme? The case of deoxyxylulose phosphate reductoisomerase
Flavonoids: True or promiscuous inhibitors of enzyme? The case of deoxyxylulose phosphate reductoisomerase Open