Denis Waast
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View article: Multimodal analysis of osteoarthritic chondrocytes reveals mitochondrial alterations and patient-specific OxPhos response to bezafibrate
Multimodal analysis of osteoarthritic chondrocytes reveals mitochondrial alterations and patient-specific OxPhos response to bezafibrate Open
Background Osteoarthritis (OA) is the most common joint disease and is characterized by bone remodeling, cartilage degradation and synovial inflammation. To date, no effective treatment is available for this debilitating condition. Recent …
View article: Targeting the colony-stimulating factor 1 axis for the treatment of Tenosynovial Giant Cell Tumors
Targeting the colony-stimulating factor 1 axis for the treatment of Tenosynovial Giant Cell Tumors Open
View article: The impact of a Diagnostic Multidisciplinary Meeting on reducing diagnostic delays in musculoskeletal tumors
The impact of a Diagnostic Multidisciplinary Meeting on reducing diagnostic delays in musculoskeletal tumors Open
IV; Retrospective study.
View article: Improved Metastatic-Free Survival after Systematic Re-Excision Following Complete Macroscopic Unplanned Excision of Limb or Trunk Soft Tissue Sarcoma
Improved Metastatic-Free Survival after Systematic Re-Excision Following Complete Macroscopic Unplanned Excision of Limb or Trunk Soft Tissue Sarcoma Open
Background: Whether re-excision (RE) of a soft tissue sarcoma (STS) of limb or trunk should be systematized as adjuvant care and if it would improve metastatic free survival (MFS) are still debated. The impact of resection margins after un…
View article: Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes
Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes Open
Senescent cells (SnCs) have been described to accumulate in osteoarthritis (OA) joint tissues in response to injury, thereby participating in OA development and progression. However, clinical therapeutic approaches targeting SnCs using sen…
View article: Osteoarthritic chondrocytes undergo a glycolysis-related metabolic switch upon exposure to IL-1b or TNF
Osteoarthritic chondrocytes undergo a glycolysis-related metabolic switch upon exposure to IL-1b or TNF Open
View article: Overall survival in patients with re-excision of positive microscopic margins of limb and trunk wall soft tissue sarcoma operated outside of a reference center: a nationwide cohort analysis
Overall survival in patients with re-excision of positive microscopic margins of limb and trunk wall soft tissue sarcoma operated outside of a reference center: a nationwide cohort analysis Open
View article: A Short-Course Antibiotic Prophylaxis Is Associated with Limited Antibiotic Resistance Emergence in Post-Operative Infection of Pelvic Primary Bone Tumor Resection
A Short-Course Antibiotic Prophylaxis Is Associated with Limited Antibiotic Resistance Emergence in Post-Operative Infection of Pelvic Primary Bone Tumor Resection Open
Resections of primary pelvic bone tumors are frequently complicated by surgical site infections (SSIs), thereby impairing the functional prognosis of patients, especially in case of implant removal. Although prophylactic antibiotics play a…
View article: Survie et complications des prothèses charnière de reconstruction du genou après résection tumorale fémorale distale ou tibiale proximale : étude rétrospective avec 161 cas
Survie et complications des prothèses charnière de reconstruction du genou après résection tumorale fémorale distale ou tibiale proximale : étude rétrospective avec 161 cas Open
View article: Survival and complications in hinged knee reconstruction prostheses after distal femoral or proximal tibial tumor resection: A retrospective study of 161 cases
Survival and complications in hinged knee reconstruction prostheses after distal femoral or proximal tibial tumor resection: A retrospective study of 161 cases Open
View article: Pharmacokinetics of Tedizolid in an Obese Patient after Bariatric Surgery
Pharmacokinetics of Tedizolid in an Obese Patient after Bariatric Surgery Open
An obese woman was treated with oral tedizolid 200 mg once daily for pseudoarthrosis 10 years after Roux-en-Y bypass surgery. Total plasma peak concentration was 2.12 mg/liter 3 h after intake, and area under the concentration-time curve f…