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View article: Global Trends in CD4 Measurement and Immunosuppression at ART Initiation Among Children With HIV
Global Trends in CD4 Measurement and Immunosuppression at ART Initiation Among Children With HIV Open
Eligibility for antiretroviral therapy is no longer based on immune criteria. In a global cohort of 97,453 children, between 2005 and 2021, we observed large declines in CD4 measurement, from 51% to 12% among <5 seconds, and from 74% to 20…
View article: Perceived usefulness of Contraceptives among Married Individuals in Rorya District
Perceived usefulness of Contraceptives among Married Individuals in Rorya District Open
The increasing use of contraception methods worldwide has allowed couples to choose the number and spacing of their children. Despite impressive achievements, contraceptive use remains low while the need for contraception is high in some o…
View article: Direct maternal deaths attributable to HIV in the era of antiretroviral therapy: evidence from three population-based HIV cohorts with verbal autopsy
Direct maternal deaths attributable to HIV in the era of antiretroviral therapy: evidence from three population-based HIV cohorts with verbal autopsy Open
Objective: To assess whether HIV is associated with an increased risk of mortality from direct maternal complications. Design: Population-based cohort study using data from three demographic surveillance sites in Eastern and Southern Afric…
View article: Evaluating mild cachexia syndrome in the HIV-positive pregnant woman
Evaluating mild cachexia syndrome in the HIV-positive pregnant woman Open
Background Immune activation and inflammation are common symptoms throughout HIV infection and lead to elevated circulating concentrations of cachectic cytokines. Aims To evaluate cachexia-like symptoms among HIV-positive and HIV-negative …
View article: Community-based antiretroviral therapy (ART) delivery for female sex workers in Tanzania: intervention model and baseline findings
Community-based antiretroviral therapy (ART) delivery for female sex workers in Tanzania: intervention model and baseline findings Open
To increase linkage to and retention in antiretroviral therapy (ART) care, we piloted a community-based, ART service delivery intervention for female sex workers (FSWs). At baseline, we recruited and collected data from 617 FSWs (intervent…
View article: Linkage to care and antiretroviral therapy initiation by testing modality among individuals newly diagnosed with HIV in Tanzania, 2014–2017
Linkage to care and antiretroviral therapy initiation by testing modality among individuals newly diagnosed with HIV in Tanzania, 2014–2017 Open
Objective To measure linkage to care and antiretroviral therapy (ART) initiation among newly diagnosed individuals with HIV in a rural Tanzanian community. Methods We included all new HIV diagnoses of adults made between 2014 and 2017 duri…
View article: Impact of linkage quality on inferences drawn from analyses using imperfectly matched data with high rates of linkage errors
Impact of linkage quality on inferences drawn from analyses using imperfectly matched data with high rates of linkage errors Open
IntroductionStudies based on high-quality linked data in developed countries show that residual linkage errors impact the bias and precision of subsequent analyses. Since 2015, we conducted point-of-contact interactive record linkage (PIRL…
View article: Point-of-contact Interactive Record Linkage (PIRL): A software tool to prospectively link demographic surveillance and health facility data
Point-of-contact Interactive Record Linkage (PIRL): A software tool to prospectively link demographic surveillance and health facility data Open
Linking a health and demographic surveillance system (HDSS) to data from a health facility that serves the HDSS population generates a research infrastructure for directly observed data on access to and utilization of health facility servi…
View article: Point-of-contact interactive record linkage (PIRL) between demographic surveillance and health facility data in rural Tanzania
Point-of-contact interactive record linkage (PIRL) between demographic surveillance and health facility data in rural Tanzania Open
IntroductionHealth and demographic surveillance systems (HDSS) have been an invaluable resource for monitoring the health status of populations, but often contain self-reported health service utilisation, which are subject to reporting bia…
View article: The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014
The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014 Open
Timely progression of people living with HIV (PLHIV) from the point of infection through the pathway from diagnosis to treatment is important in ensuring effective care and treatment of HIV and preventing HIV-related deaths and onwards tra…
View article: Point-of-contact Interactive Record Linkage (PIRL): A software tool to prospectively link demographic surveillance and health facility data
Point-of-contact Interactive Record Linkage (PIRL): A software tool to prospectively link demographic surveillance and health facility data Open
Linking a health and demographic surveillance system (HDSS) to data from a health facility that serves the HDSS population generates a research infrastructure for directly observed data on access to and utilization of health facility servi…
View article: Low implementation of Xpert MTB/RIF among HIV/TB co-infected adults in the International epidemiologic Databases to Evaluate AIDS (IeDEA) program
Low implementation of Xpert MTB/RIF among HIV/TB co-infected adults in the International epidemiologic Databases to Evaluate AIDS (IeDEA) program Open
In this cohort, Xpert utilization was low even though the majority of sites had access to the test. Our findings show the need for expanded implementation and further research exploring barriers to use in low-resource settings.
View article: Prevalence,awareness and factors associated with hypertension in North West Tanzania
Prevalence,awareness and factors associated with hypertension in North West Tanzania Open
By integrating blood pressure screening into our long-standing community HIV screening program, we were able to identify many previously undiagnosed cases of hypertension and pre-hypertension. Age, residence, overweight and obesity were th…
View article: Identifying gaps in HIV service delivery across the diagnosis‐to‐treatment cascade: findings from health facility surveys in six sub‐Saharan countries
Identifying gaps in HIV service delivery across the diagnosis‐to‐treatment cascade: findings from health facility surveys in six sub‐Saharan countries Open
Introduction: Despite the rollout of antiretroviral therapy (ART), challenges remain in ensuring timely access to care and treatment for people living with HIV. As part of a multi‐country study to investigate HIV mortality, we conducted he…
View article: The effects of HIV on fertility by infection duration
The effects of HIV on fertility by infection duration Open
Longer duration of infection is associated with greater relative fertility reduction for HIV-positive women. This should be considered when creating estimates for HIV prevalence among pregnant women and prevention of mother-to-child transm…
View article: The feasibility and acceptability of screening for hypertension in private drug retail outlets: a pilot study in Mwanza region, Tanzania
The feasibility and acceptability of screening for hypertension in private drug retail outlets: a pilot study in Mwanza region, Tanzania Open
Blood pressure screening was feasible and acceptable to customers of private drug retail outlets. However many who were referred failed to attend at a referral centre and further research is needed in this area.
View article: Data Resource Profile: Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA Network)
Data Resource Profile: Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA Network) Open
The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA Network, http://alpha.lshtm.ac.uk/) brings together ten population-based HIV surveillance sites in eastern and southern Africa, and is coordinated by th…
View article: Additional file 1: of Uptake of services for prevention of mother-to-child transmission of HIV in a community cohort in rural Tanzania from 2005 to 2012
Additional file 1: of Uptake of services for prevention of mother-to-child transmission of HIV in a community cohort in rural Tanzania from 2005 to 2012 Open
Adjusted coverage estimates for the proportion of HIV-positive pregnant women who a) accessed ANC, b) enrolled in care at PMTCT/CTC, and c) accessed ARVs, in each pregnancy by year. (XLSX 13 kb)
View article: Challenges with routine data sources for PMTCT programme monitoring in East Africa: insights from Tanzania
Challenges with routine data sources for PMTCT programme monitoring in East Africa: insights from Tanzania Open
Routinely collected clinic data have the potential to provide much needed information on the uptake of services to prevent mother-to-child transmission (PMTCT) of HIV, and to measure HIV prevalence in pregnant women. This article describes…
View article: Factors associated with uptake of services to prevent mother-to-child transmission of HIV in a community cohort in rural Tanzania
Factors associated with uptake of services to prevent mother-to-child transmission of HIV in a community cohort in rural Tanzania Open
Access to PMTCT services was low in this rural setting but improved markedly over time. There were fairly few sociodemographic differentials although support for young women and those without partners may be needed. Further decentralisatio…
View article: Utilization of cervical cancer screening services and its associated factors among primary school teachers in Ilala Municipality, Dar es Salaam, Tanzania
Utilization of cervical cancer screening services and its associated factors among primary school teachers in Ilala Municipality, Dar es Salaam, Tanzania Open
The study has demonstrated low level of utilization of cervical cancer screening service among female primary school teachers in Ilala munipality. Female primary school teachers with more than one previous pregnancy and those with more tha…
View article: Effects on mortality of a nutritional intervention for malnourished HIV-infected adults referred for antiretroviral therapy: a randomised controlled trial
Effects on mortality of a nutritional intervention for malnourished HIV-infected adults referred for antiretroviral therapy: a randomised controlled trial Open
PACTR201106000300631, registered on 1st June 2011.