Dennis Pultz
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View article: Gene finding revisited: improved robustness through structured decoding from learned embeddings
Gene finding revisited: improved robustness through structured decoding from learned embeddings Open
Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…
View article: BEND: Benchmarking DNA Language Models on biologically meaningful tasks
BEND: Benchmarking DNA Language Models on biologically meaningful tasks Open
The genome sequence contains the blueprint for governing cellular processes. While the availability of genomes has vastly increased over the last decades, experimental annotation of the various functional, non-coding and regulatory element…
View article: A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy.
A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy. Open
Temporal lobe epilepsy is the most common drug-resistant form of epilepsy in adults. The reorganization of neural networks and the gene expression landscape underlying pathophysiologic network behavior in brain structures such as the hippo…
View article: A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy
A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy Open
Temporal lobe epilepsy is the most common drug-resistant form of epilepsy in adults. The reorganization of neural networks and the gene expression landscape underlying pathophysiologic network behavior in brain structures such as the hippo…
View article: Ago2-seq identifies new microRNA targets for seizure control
Ago2-seq identifies new microRNA targets for seizure control Open
MicroRNAs (miRNAs) are short noncoding RNAs that shape the gene expression landscape, including during the pathogenesis of temporal lobe epilepsy (TLE). In order to provide a full catalog of the miRNA changes that happen during experimenta…
View article: TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy
TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy Open
(Cell Reports 5, 1036–1046; November 27, 2013) In the originally published version of this article, part of a panel shown in Figure 3D was inadvertently duplicated from Figure 3C during preparation of the figure. The correct version of thi…