Dennis W. Jay
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View article: Kidney Function and Body Composition in Adult Survivors of Unilateral, Non‐Syndromic Wilms Tumor: A Report From the St. Jude Lifetime Cohort Study
Kidney Function and Body Composition in Adult Survivors of Unilateral, Non‐Syndromic Wilms Tumor: A Report From the St. Jude Lifetime Cohort Study Open
Background The relationships among treatment exposures, body composition, and estimated glomerular filtration rate (eGFR) in adult survivors of Wilms tumor have not been well studied. Methods We evaluated body composition with dual‐energy …
View article: The accuracy of estimating equations for the evaluation of kidney function in adult survivors of unilateral, nonmetastatic, non‐syndromic Wilms tumor: A pilot study from the St. Jude Lifetime Cohort Study
The accuracy of estimating equations for the evaluation of kidney function in adult survivors of unilateral, nonmetastatic, non‐syndromic Wilms tumor: A pilot study from the St. Jude Lifetime Cohort Study Open
Background Adult survivors of unilateral, nonmetastatic, non‐syndromic Wilms tumor (WT) treated with whole abdomen radiation therapy (WART) are at risk for impaired kidney function. The impact of bias and accuracy on estimated glomerular f…
View article: Kidney Function after Treatment for Childhood Cancer: A Report from the St. Jude Lifetime Cohort Study
Kidney Function after Treatment for Childhood Cancer: A Report from the St. Jude Lifetime Cohort Study Open
Significance Statement Although associations of treatment for childhood cancer with acute kidney toxicity are well described, evidence informing late kidney sequelae is less robust. The authors evaluated the prevalence of and factors assoc…
View article: Long‐term renal function after treatment for unilateral, nonsyndromic Wilms tumor. A report from the St. Jude Lifetime Cohort Study
Long‐term renal function after treatment for unilateral, nonsyndromic Wilms tumor. A report from the St. Jude Lifetime Cohort Study Open
Background The impact of specific treatment modalities on long‐term renal function and blood pressure among adult survivors of Wilms tumor (WT) has not been well documented. Methods Among 40 WT survivors and 35 noncancer controls, we estim…
View article: No evidence that G6PD deficiency affects the efficacy or safety of daunorubicin in acute lymphoblastic leukemia induction therapy
No evidence that G6PD deficiency affects the efficacy or safety of daunorubicin in acute lymphoblastic leukemia induction therapy Open
Background/Objectives Anthracyclines are used in induction therapy of pediatric acute lymphoblastic leukemia (ALL) and are known to generate oxidative stress; whether this translates into enhanced antileukemic activity or hemolytic effects…
View article: Serum Alanine Aminotransferase Elevations in Survivors of Childhood Cancer: A Report From the St. Jude Lifetime Cohort Study
Serum Alanine Aminotransferase Elevations in Survivors of Childhood Cancer: A Report From the St. Jude Lifetime Cohort Study Open
The purpose of this study was to define the prevalence of and risk factors for elevated serum alanine aminotransferase (ALT) level among adult childhood cancer survivors (CCS). The study cohort comprised 2,751 CCS from the St. Jude Lifetim…
View article: Prevention of conversion to abnormal transcranial <scp>D</scp>oppler with hydroxyurea in sickle cell anemia: A <scp>P</scp>hase III international randomized clinical trial
Prevention of conversion to abnormal transcranial <span>D</span>oppler with hydroxyurea in sickle cell anemia: A <span>P</span>hase III international randomized clinical trial Open
Children with sickle cell anemia (SCA) and conditional transcranial Doppler (TCD) ultrasound velocities (170–199 cm/sec) may develop stroke. However, with limited available clinical data, the current standard of care for conditional TCD ve…