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View article: Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation
Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation Open
A hallmark of cardiac development is the formation of myocardial trabeculations exclusively from the luminal surface of the primitive heart tube. Although a number of genetic defects in the endocardium and cardiac jelly disrupt myocardial …
View article: Fetal Mammalian Heart Generates a Robust Compensatory Response to Cell Loss
Fetal Mammalian Heart Generates a Robust Compensatory Response to Cell Loss Open
Background— Heart development is tightly regulated by signaling events acting on a defined number of progenitor and differentiated cardiac cells. Although loss of function of these signaling pathways leads to congenital malformation, the c…