Derek Q. Nesbitt
YOU?
Author Swipe
View article: Increased deformations are dispensable for encapsulated cell mechanoresponse in engineered bone analogs mimicking aging bone marrow
Increased deformations are dispensable for encapsulated cell mechanoresponse in engineered bone analogs mimicking aging bone marrow Open
Aged individuals and astronauts experience bone loss despite rigorous physical activity. Bone mechanoresponse is in-part regulated by mesenchymal stem cells (MSCs) that respond to mechanical stimuli. Direct delivery of low intensity vibrat…
View article: Age‐dependent changes in collagen crosslinks reduce the mechanical toughness of human meniscus
Age‐dependent changes in collagen crosslinks reduce the mechanical toughness of human meniscus Open
The mechanical resilience of the knee meniscus is provided by a group of structural proteins in the extracellular matrix. Aging can alter the quantity and molecular structure of these proteins making the meniscus more susceptible to debili…
View article: Increased deformations are dispensable for cell mechanoresponse in engineered bone analogs mimicking aging bone marrow
Increased deformations are dispensable for cell mechanoresponse in engineered bone analogs mimicking aging bone marrow Open
Aged individuals and astronauts experience bone loss despite rigorous physical activity. Bone mechanoresponse is in-part regulated by mesenchymal stem cells (MSCs) that respond to mechanical stimuli. Direct delivery of low intensity vibrat…
View article: Dots-on-Plots: A Web Application to Analyze Stress–Strain Curves From Tensile Tests of Soft Tissue
Dots-on-Plots: A Web Application to Analyze Stress–Strain Curves From Tensile Tests of Soft Tissue Open
The calculation of tensile mechanical properties from stress–strain curves is a fundamental step in characterizing material behavior, yet no standardized method exists to perform these calculations for soft tissue. To address this deficien…
View article: Applying ASTM Standards to Tensile Tests of Musculoskeletal Soft Tissue: Methods to Reduce Grip Failures and Promote Reproducibility
Applying ASTM Standards to Tensile Tests of Musculoskeletal Soft Tissue: Methods to Reduce Grip Failures and Promote Reproducibility Open
Tensile testing is an essential experiment to assess the mechanical integrity of musculoskeletal soft tissues, yet standard test methods have not been developed to ensure the quality and reproducibility of these experiments. The ASTM Inter…
View article: High-Speed Strain Mapping of Human Meniscus During Tensile Loading
High-Speed Strain Mapping of Human Meniscus During Tensile Loading Open
The knee meniscus is a fibrous soft tissue that is frequently torn. Prevention and treatment requires an understanding of failure mechanisms. Important failure properties are currently unknown, including the magnitude and orientation of pr…