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View article: Impact of a Clinical Valve Coordinator on hospital length of stay and patient outcomes: Results from the BENCHMARK registry
Impact of a Clinical Valve Coordinator on hospital length of stay and patient outcomes: Results from the BENCHMARK registry Open
View article: Bipolar Catheter Ablation as a Key for Successful Treatment of Intramural VentricuLar Arrhythmias: Results From the Bipolar‐Kiel Study
Bipolar Catheter Ablation as a Key for Successful Treatment of Intramural VentricuLar Arrhythmias: Results From the Bipolar‐Kiel Study Open
Background Unipolar catheter ablation (CA) is effective in the treatment of ventricular arrhythmias but its efficacy can be limited in eliminating intramural arrhythmic origins. Bipolar ablation has emerged as a bail‐out strategy. However,…
View article: Subdomains of Post-COVID Syndrome (PCS) – a population-based study
Subdomains of Post-COVID Syndrome (PCS) – a population-based study Open
View article: Elevated levels of Letm1 drives mitochondrial dysfunction and cardiomyocyte stress-mediated apoptosis in cultured cardiomyocytes
Elevated levels of Letm1 drives mitochondrial dysfunction and cardiomyocyte stress-mediated apoptosis in cultured cardiomyocytes Open
View article: Strengthening the leadership and nurses and allied professionals to support patients with valvular heart disease: Evidence to support the role of clinical valve coordinators
Strengthening the leadership and nurses and allied professionals to support patients with valvular heart disease: Evidence to support the role of clinical valve coordinators Open
Background The central role of the Clinical Valve Coordinator (CVC) has been endorsed by international guidelines to provide unique expertise for programs that deliver comprehensive care to patients with valvular heart disease. Conventiona…
View article: Safety of ventricular tachycardia ablation under deep sedation with propofol and fentanyl
Safety of ventricular tachycardia ablation under deep sedation with propofol and fentanyl Open
Background There is no current standard of anaesthetic management for CA of VT. Data on VT ablation under deep sedation with propofol and fentanyl are limited. Objective The aim was to evaluate the feasibility and safety of CA of VT under …
View article: A Novel Approach for Localizing Non‐Sustained Atrial Arrhythmias: Atrial Pace‐Mapping With Automatic Intracardiac Pattern Matching
A Novel Approach for Localizing Non‐Sustained Atrial Arrhythmias: Atrial Pace‐Mapping With Automatic Intracardiac Pattern Matching Open
Introduction Ventricular pace mapping is an established tool to identify the origin of non‐inducible arrhythmias by analyzing the paced QRS morphology of the surface electrocardiogram (ECG). Using the same approach for atrial pace mapping …
View article: Information Needs of Patients with Inflammatory Bowel Disease in the Digital Era: A 20-Year Longitudinal Study
Information Needs of Patients with Inflammatory Bowel Disease in the Digital Era: A 20-Year Longitudinal Study Open
Background: Chronic inflammatory bowel disease significantly impacts patients’ everyday lives. Despite receiving regular medical care in gastroenterological or family medicine consultations, patients with inflammatory bowel disease (IBD) s…
View article: When a subclavian artery is equivalent to STEMI of left main coronary artery: a case report
When a subclavian artery is equivalent to STEMI of left main coronary artery: a case report Open
An 81-year-old man with known ischemic heart disease and coronary artery bypass graft (CABG) was admitted with cardiogenic shock and ST segment elevation myocardial infarction (STEMI) of the anterior and lateral wall. Coronary angiography …
View article: A novel approach for localizing non-pulmonary vein triggers: atrial pace mapping with automatic intracardiac pattern matching
A novel approach for localizing non-pulmonary vein triggers: atrial pace mapping with automatic intracardiac pattern matching Open
Background and Aims Atrial pace mapping (APM) is a tool for localizing the origin of non-sustained atrial tachycardia (nsAT), or atrial fibrillation (AF) triggers, commonly not amenable to activation mapping. However, the conventional appr…
View article: Dispersion of intracardiac pattern during sustained monomorphic atrial tachycardia
Dispersion of intracardiac pattern during sustained monomorphic atrial tachycardia Open
Background and Aims Automatic intracardiac pattern matching (aICPM) can be used to monitor the stability of atrial tachycardia (AT) during activation mapping or to perform an atrial pace mapping (APM) for localizing the origin of non-susta…
View article: Hemodynamic and respiratory stability in obese vs. non-obese patients during de novo pulmonary vein isolation under conscious sedation
Hemodynamic and respiratory stability in obese vs. non-obese patients during de novo pulmonary vein isolation under conscious sedation Open
Background Pulmonary vein isolation (PVI) was shown to be safe and effective in obese patients. However, the periprocedural management during catheter ablation (CA) of atrial fibrillation (AF) in obese patients under conscious sedation (CS…
View article: Electroanatomical properties of the superior vena cava - the vein, born for isolation
Electroanatomical properties of the superior vena cava - the vein, born for isolation Open
Background Superior vena cava (SVC) is a known source of non-pulmonary vein (non-PV) triggers. SVC isolation (SVCI) plays an important role in treatment of atrial fibrillation (AF). However, the proximity of the phrenic nerve and sinus nod…
View article: Bipolar radiofrequency catheter ablation in the treatment of 
cardiac arrhythmias - single center experience
Bipolar radiofrequency catheter ablation in the treatment of 
cardiac arrhythmias - single center experience Open
Background Catheter ablation has emerged as a primary choice of treatment for many arrhythmias. While unipolar ablation is sufficient in the treatment of the majority of arrhythmias, its acute and long term efficacy can be limited in speci…
View article: Information Needs of Patients with Inflammatory Bowel Disease in the Digital Era: A 20-Year Longitudinal Study
Information Needs of Patients with Inflammatory Bowel Disease in the Digital Era: A 20-Year Longitudinal Study Open
Background Chronic inflammatory bowel disease (IBD) significantly impacts patients' everyday lives. Despite receiving regular medical care in gastroenterological consultations, patients with IBD still experience a lack of information. To e…
View article: The implementation of a streamlined TAVI patient pathway across five European countries: BENCHMARK registry
The implementation of a streamlined TAVI patient pathway across five European countries: BENCHMARK registry Open
View article: Transcatheter tricuspid valve replacement: will it prevail?
Transcatheter tricuspid valve replacement: will it prevail? Open
Severe tricuspid regurgitation (TR) is a prevalent and challenging condition associated with poor survival outcomes and significant morbidity. Medical therapy alone often fails to provide adequate symptom relief, and stand-alone surgical i…
View article: Complete revascularization versus culprit-lesion only PCI in patients with NSTEMI and multivessel disease – Design and rationale of the randomized COMPLETE-NSTEMI trial
Complete revascularization versus culprit-lesion only PCI in patients with NSTEMI and multivessel disease – Design and rationale of the randomized COMPLETE-NSTEMI trial Open
CLINICALTRIALS.GOV: NCT05786131.
View article: Toronto Aortic Stenosis Quality of Life Questionnaire (TASQ): Validation in Polish Patients with Aortic Stenosis
Toronto Aortic Stenosis Quality of Life Questionnaire (TASQ): Validation in Polish Patients with Aortic Stenosis Open
Background/Objectives: Quality of life (QoL) is recognized as a clinically significant outcome measure among patients with aortic stenosis (AS). However, there is no validated, AS-specific questionnaire available in Poland for assessing th…
View article: XBP1s-EDEM2 Prevents the Onset and Development of HFpEF by Ameliorating Cardiac Lipotoxicity
XBP1s-EDEM2 Prevents the Onset and Development of HFpEF by Ameliorating Cardiac Lipotoxicity Open
BACKGROUND: Morbidity and mortality of heart failure with preserved ejection fraction (HFpEF) is increased in metabolic disorders. However, options for preventing and treating these prevalent outcomes are limited. Intramyocardial lipotoxic…
View article: Prediction of Ablation Index and Lesion Size Index for Local Impedance Drop-Guided Ablation
Prediction of Ablation Index and Lesion Size Index for Local Impedance Drop-Guided Ablation Open
(1) Background: The effectiveness of RF ablation for PVI depends on the lesion location and size to achieve continuous and durable lesion lines. AI and LSI are widely accepted lesion metrics for guiding the ablation procedure. LI dynamics …
View article: AAV library screening identifies novel vector for efficient transduction of human aorta
AAV library screening identifies novel vector for efficient transduction of human aorta Open
Targeted gene delivery to vascular smooth muscle cells (VSMCs) could prevent or improve a variety of diseases affecting the vasculature and particularly the aorta. Thus, we aimed to develop a delivery vector that efficiently targets VSMCs.…
View article: Eccentric hypertrophy impairs outcome after TAVR
Eccentric hypertrophy impairs outcome after TAVR Open
View article: Assessing Patient Health Dynamics by Comparative CT Analysis: An Automatic Approach to Organ and Body Feature Evaluation
Assessing Patient Health Dynamics by Comparative CT Analysis: An Automatic Approach to Organ and Body Feature Evaluation Open
Background/Objectives: The integration of machine learning into the domain of radiomics has revolutionized the approach to personalized medicine, particularly in oncology. Our research presents RadTA (RADiomics Trend Analysis), a novel fra…
View article: Timing of veno‐arterial extracorporeal membrane oxygenation support in patients with cardiogenic shock
Timing of veno‐arterial extracorporeal membrane oxygenation support in patients with cardiogenic shock Open
Aims The optimal timing for implementing mechanical circulatory support (MCS) in cardiogenic shock (CS) remains indeterminate. This study aims to evaluate patient characteristics and outcome associated with the time interval between CS ons…
View article: Computed tomography for the detection of myocardial hypoperfusion in acute myocardial infarction and the associated CT-to-catheter time
Computed tomography for the detection of myocardial hypoperfusion in acute myocardial infarction and the associated CT-to-catheter time Open
Emergency computed tomography (CT) often does not allow for comprehensive coronary artery assessment. However, CT may reveal pathological myocardial hypoperfusion suggestive of acute myocardial infarction (AMI), especially in patients pres…
View article: Implementation of an Atrioventricular Valve Intervention Registry: Comparative Study of REDCap vs. CDR-Based openEHR Registry
Implementation of an Atrioventricular Valve Intervention Registry: Comparative Study of REDCap vs. CDR-Based openEHR Registry Open
This comparative study examines the transition from isolated registries to a consolidated data-centric approach at University Hospital Schleswig-Holstein, focusing on migrating the Atrioventricular Valve Intervention Registry (AVIR) from R…
View article: Endothelial derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodeling
Endothelial derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodeling Open
Pathological cardiac remodeling predisposes individuals to developing heart failure. Here, we investigated two co-regulated long non-coding RNAs (lncRNAs), termed Gadlor1 and Gadlor2, which are upregulated in failing hearts o…
View article: Local impedance drop–guided versus lesion size index–guided pulmonary vein isolation
Local impedance drop–guided versus lesion size index–guided pulmonary vein isolation Open
Background Local tissue impedance drop (LID) and lesion size index (LSI) technologies are valuable for predicting effective lesion formation. This study compares the acute and long-term efficacy of LID-guided versus LSI-guided pulmonary ve…
View article: Transcatheter aortic valve replacement in patients with severe aortic valve stenosis and concomitant mitral valve regurgitation – 5 years follow-up
Transcatheter aortic valve replacement in patients with severe aortic valve stenosis and concomitant mitral valve regurgitation – 5 years follow-up Open