Derrick Lopez
YOU?
Author Swipe
View article: Counts, Characteristics and Outcomes of Patients Transported by the Royal Flying Doctor Service to Metropolitan Perth With Suspected Acute Coronary Syndrome: Western Australian Linked Data Study
Counts, Characteristics and Outcomes of Patients Transported by the Royal Flying Doctor Service to Metropolitan Perth With Suspected Acute Coronary Syndrome: Western Australian Linked Data Study Open
Objectives Determine counts, characteristics and outcomes following transport by the Royal Flying Doctor Service Western Operations (RFDSWO) to Perth. Study Design Retrospective cohort study of the RFDSWO aeromedical patient dataset linked…
View article: ASSESSMENT OF QUALITY OF LIFE IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS USING THE PBC-27 QUESTIONNAIRE AT A TERTIARY CARE CENTER
ASSESSMENT OF QUALITY OF LIFE IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS USING THE PBC-27 QUESTIONNAIRE AT A TERTIARY CARE CENTER Open
Introduction and Objectives: Primary biliary cholangitis (PBC) is a chronic liver disease that significantly impacts patients’ quality of life due to persistent symptoms like fatigue, pruritus, and emotional or cognitive disturbances. Unde…
View article: Effects of the COVID-19 pandemic and ‘Find Cancer Early’ campaign on cancer symptom knowledge in regional Western Australia
Effects of the COVID-19 pandemic and ‘Find Cancer Early’ campaign on cancer symptom knowledge in regional Western Australia Open
Background Awareness of cancer and its symptoms may have declined in 2020 following the onset of the COVID-19 pandemic. We examined the effect of the COVID-19 pandemic and awareness of the ‘Find Cancer Early’ mass media campaign on the kno…
View article: Identifying episodes of care in hospital admissions data for measures of disease burden: A tutorial and protocol for individual-level data analysis
Identifying episodes of care in hospital admissions data for measures of disease burden: A tutorial and protocol for individual-level data analysis Open
Appropriate data processing is vital to derive accurate results from hospital admissions data. We have presented open source, live syntax for this purpose.
View article: Comparative Algorithms for Identifying and Counting Hospitalisation Episodes of Care for Coronary Heart Disease Using Administrative Data
Comparative Algorithms for Identifying and Counting Hospitalisation Episodes of Care for Coronary Heart Disease Using Administrative Data Open
The date and datetime algorithms produced the most valid measures of CHD and MI episodes. Findings underscore the importance of identifying admission and discharge dates/times belonging to the same individual in enumerating these episodes.
View article: Temporal trends in concordance between ICD-coded and cardiac biomarker-classified hospitalisation rates for acute coronary syndromes: a linked hospital and biomarker data study
Temporal trends in concordance between ICD-coded and cardiac biomarker-classified hospitalisation rates for acute coronary syndromes: a linked hospital and biomarker data study Open
Background Since 2000, the definition of myocardial infarction (MI) has evolved with reliance on cardiac troponin (cTn) tests. The implications of this change on trends of acute coronary syndrome (ACS) subtypes obtained from routinely coll…
View article: Supply of nirmatrelvir/ritonavir and molnupiravir for patients with COVID-19 in the first eight months since listing on the Australian Pharmaceutical Benefits Scheme: A retrospective observational study
Supply of nirmatrelvir/ritonavir and molnupiravir for patients with COVID-19 in the first eight months since listing on the Australian Pharmaceutical Benefits Scheme: A retrospective observational study Open
Many prescriptions were written for molnupiravir where there were no contraindications to nirmatrelvir/ritonavir. The benefits that followed from prompt government action in approving and obtaining nirmatrelvir/ritonavir were therefore lik…
View article: Process evaluation of a maintenance pulmonary rehabilitation trial for people with chronic obstructive pulmonary disease
Process evaluation of a maintenance pulmonary rehabilitation trial for people with chronic obstructive pulmonary disease Open
Background The ComEx3 community‐based extended maintenance pulmonary rehabilitation (PR) randomised controlled trial (RCT) aimed to determine the optimal strategy for maintaining the benefits of exercise for people with chronic obstructive…
View article: Medicine utilization studies in Australian individual‐level dispensing data: A blinded, multi‐center replicated analysis
Medicine utilization studies in Australian individual‐level dispensing data: A blinded, multi‐center replicated analysis Open
Purpose Medicine dispensing data require extensive preparation when used for research and decisions during this process may lead to results that do not replicate between independent studies. We conducted an experiment to examine the impact…
View article: Evaluation of the awareness of Western Australian <scp>SunSmart</scp> campaigns between 2008 and 2022
Evaluation of the awareness of Western Australian <span>SunSmart</span> campaigns between 2008 and 2022 Open
Issue Addressed It is unknown whether SunSmart health promotion campaigns in Western Australia are still effectively reaching their target audience of young people (under 45 years). This study examined trends over time in awareness, releva…
View article: Characteristics and risk of coronary-related events following hospitalisation for chronic coronary disease
Characteristics and risk of coronary-related events following hospitalisation for chronic coronary disease Open
Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): Western Australian Department of Health. Background Chronic coronary heart disease (CCD) is associated with a high healthcare burden and expen…
View article: Temporal trends in acute coronary syndrome hospitalisation rates: a comparison of administrative diagnosis coding and cardiac biomarker testing
Temporal trends in acute coronary syndrome hospitalisation rates: a comparison of administrative diagnosis coding and cardiac biomarker testing Open
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Victor Chang Cardiac Research Institute. Background/aims Accurate monitoring of trends in acute coronary syndromes (ACS) provides important information o…
View article: Risk of Major Adverse Cardiovascular Event Following Incident Hospitalization for Acute Gout: A Western Australian <scp>Population‐Level</scp> Linked Data Study
Risk of Major Adverse Cardiovascular Event Following Incident Hospitalization for Acute Gout: A Western Australian <span>Population‐Level</span> Linked Data Study Open
Background Cardiovascular disease is the most common cause of death in people with gout. Acute inflammation, which is a characteristic of gout, may have a mechanistic role in major adverse cardiovascular events (MACEs). We aimed to examine…
View article: Risk of a major adverse cardiovascular event (MACE) following first-ever hospitalisation for acute gout: a Western Australian population-level linked data study.
Risk of a major adverse cardiovascular event (MACE) following first-ever hospitalisation for acute gout: a Western Australian population-level linked data study. Open
ObjectivesCardiovascular disease is the largest contributor of increased mortality in patients with gout. Acute inflammation as seen with gout attacks may have a mechanistic role in developing Major Adverse Cardiovascular Events (MACE). We…
View article: Priorities for building Australian workforce capacity to leverage population-based, routinely collected data: views from pharmacoepidemiology
Priorities for building Australian workforce capacity to leverage population-based, routinely collected data: views from pharmacoepidemiology Open
Aim:To explore perspectives of leaders in pharmacoepidemiology on building workforce capacity in the routinely collected data arena to enable researchers to generate evidence to support clinical and policy decision-making. Methods: Semi-st…
View article: Incidence of Newly Registered Blindness From Age-Related Macular Degeneration in Australia Over a 21-Year Period: 1996–2016
Incidence of Newly Registered Blindness From Age-Related Macular Degeneration in Australia Over a 21-Year Period: 1996–2016 Open
The increase in new blindness registrations due to AMD coincided with public funding of verteporfin for PDT, whereas the subsequent decline occurred when bevacizumab was used off-label and ranibizumab and aflibercept were publicly funded. …
View article: Supplementary Material for: Optimal measures for primary care physician encounters after stroke and association with survival: a data linkage study
Supplementary Material for: Optimal measures for primary care physician encounters after stroke and association with survival: a data linkage study Open
Background and Purpose: Primary care physicians provide ongoing management after stroke. However, little is known about how best to measure physician encounters with reference to longer term outcomes. We aimed to compare methods for measur…
View article: Evaluating Machine-Learning Models for Predicting Hospital Transfers in Administrative Data: A Study of Admissions for Myocardial Infarction
Evaluating Machine-Learning Models for Predicting Hospital Transfers in Administrative Data: A Study of Admissions for Myocardial Infarction Open
IntroductionHospital administrative data is a valuable source to measure myocardial infarction (MI) rates. However, admission counts are susceptible to over-inflation if the patient is transferred multiple times during a single episode of …
View article: Frailty and Initiation of Cardio-Protective Medicines Following Incident Acute Coronary Syndrome in Older People: A Linked Data Study
Frailty and Initiation of Cardio-Protective Medicines Following Incident Acute Coronary Syndrome in Older People: A Linked Data Study Open
IntroductionBeta-blockers, renin-angiotensin system inhibitors and statins are evidence-based pharmacotherapies for preventing recurrent acute coronary syndrome (ACS), however their use in older people may depend on clinical factors such a…
View article: Patterns of Use and Discontinuation of Secondary Prevention Medications After Stroke
Patterns of Use and Discontinuation of Secondary Prevention Medications After Stroke Open
Patterns of use of secondary prevention medications after stroke/TIA are not optimal, with many survivors discontinuing treatment within 1 year postdischarge. Improving postdischarge care for patients with stroke/TIA is needed to minimize …
View article: Assuming one dose per day yields a similar estimate of medication adherence in patients with stroke: An exploratory analysis using linked registry data
Assuming one dose per day yields a similar estimate of medication adherence in patients with stroke: An exploratory analysis using linked registry data Open
Purpose Prescribed daily dose (PDD), the number of doses prescribed to be taken per day, is used to calculate medication adherence using pharmacy claims data. PDD can be substituted by (i) one dose per day (1DD), (ii) an estimate based on …
View article: Maintaining quality of life in patients with chronic obstructive pulmonary disease (COPD) by extending the maintenance phase of community-based pulmonary rehabilitation: protocol for a randomised controlled trial (ComEx3 Study)
Maintaining quality of life in patients with chronic obstructive pulmonary disease (COPD) by extending the maintenance phase of community-based pulmonary rehabilitation: protocol for a randomised controlled trial (ComEx3 Study) Open
Introduction Pulmonary rehabilitation is a core component of the treatment of people with chronic obstructive pulmonary disease (COPD); however, the benefits gained diminish in the ensuing months. The optimal strategy for maintaining the b…
View article: Online-Only Data Supplement: Patterns of Use and Discontinuation of Secondary Prevention Medications After Stroke
Online-Only Data Supplement: Patterns of Use and Discontinuation of Secondary Prevention Medications After Stroke Open
Online-Only Data Supplement relating to research article: Patterns of Use and Discontinuation of Secondary Prevention Medications After Stroke (doi:10.1212/WNL.0000000000011083)
View article: P60 Comparative trends in coronary heart disease subgroup hospitalisation rates in england and australia: a population-based observational study, 1996–2013
P60 Comparative trends in coronary heart disease subgroup hospitalisation rates in england and australia: a population-based observational study, 1996–2013 Open
Background Population-based coronary heart disease (CHD) studies have historically focused on myocardial infarction (MI) with limited data on trends across the spectrum of CHD. We investigated trends in hospitalisation rates for acute and …
View article: Comparative trends in coronary heart disease subgroup hospitalisation rates in England and Australia
Comparative trends in coronary heart disease subgroup hospitalisation rates in England and Australia Open
Background Population-based coronary heart disease (CHD) studies have focused on myocardial infarction (MI) with limited data on trends across the spectrum of CHD. We investigated trends in hospitalisation rates for acute and chronic CHD s…
View article: Needs and priority areas for building capacity for working with linked data in the Australian pharmacoepidemiology workforce
Needs and priority areas for building capacity for working with linked data in the Australian pharmacoepidemiology workforce Open
IntroductionLinked data are increasingly used in pharmacoepidemiology studies to enhance value beyond that which can be achieve from stand-alone pharmaceutical data. The complexity of pharmaceutical data can make any linked data analysis c…
View article: Identification of myocardial infarction type from electronic hospital data in England and Australia: a comparative data linkage study
Identification of myocardial infarction type from electronic hospital data in England and Australia: a comparative data linkage study Open
Objective To determine the utility of International Classification of Diseases (ICD) codes in investigating trends in ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI) using pers…