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View article: In vitro and in silico assessment of antidiabetic and antioxidant potencies of secondary metabolites from Gymnema sylvestre
In vitro and in silico assessment of antidiabetic and antioxidant potencies of secondary metabolites from Gymnema sylvestre Open
This study investigated the chemical constituents, antioxidant potential, and in vitro and in silico antidiabetic activity of Gymnema sylvestre. Column chromatography and spectroscopic techniques identified twelve compounds from the methan…
View article: Antileishmanial and Antiplasmodial Activities of Secondary Metabolites from the Root of Antrocaryon klaineanum Pierre (Anacardiaceae)
Antileishmanial and Antiplasmodial Activities of Secondary Metabolites from the Root of Antrocaryon klaineanum Pierre (Anacardiaceae) Open
Antrocaryon klaineanum is traditionally used for the treatment of back pain, malaria, female sterility, chlamydiae infections, liver diseases, wounds, and hemorrhoid. This work aimed at investigating the bioactive compounds with antileishm…
View article: Molecular Docking, Pharmacokinetics and Molecular Dynamics Simulation Studies of Some Bioactive Compounds Isolated from Entandrophragma congoënse for Antiplasmodial Activity
Molecular Docking, Pharmacokinetics and Molecular Dynamics Simulation Studies of Some Bioactive Compounds Isolated from Entandrophragma congoënse for Antiplasmodial Activity Open
As a follow-up to earlier reported works on the phytochemical study of some isolated bioactive compounds from the root and bark of Entandrophragma congoënse as potent anti-plasmodium drugs (Happi et. al.2005), some of the isolated compound…
View article: Antioxidant content and activity of stem and leaf extracts of Gouania longipetala Hemsl. (Rhamnaceae)
Antioxidant content and activity of stem and leaf extracts of Gouania longipetala Hemsl. (Rhamnaceae) Open
Background: Gouania longipetala Hemsl. is a scandent shrub used in traditional medicine for the management of different ailments such as gout, female infertility, heart diseases, diabetes, and malaria. Pathophysiology of the diseases is ge…
View article: NMR data of Lanostane Type Triterpenoids isolated from Leplaea mayombensis
NMR data of Lanostane Type Triterpenoids isolated from Leplaea mayombensis Open
This folder contains NMR datasets of new compounds described in the publication entitled: Antiplasmodial and Cytotoxic Activity of Lanostane Type Triterpenoids isolated from Leplaea mayombensis NMR processing : Topspin 4.1.13
View article: NMR data of Lanostane Type Triterpenoids isolated from Leplaea mayombensis
NMR data of Lanostane Type Triterpenoids isolated from Leplaea mayombensis Open
This folder contains NMR datasets of new compounds described in the publication entitled: Antiplasmodial and Cytotoxic Activity of Lanostane Type Triterpenoids isolated from Leplaea mayombensis NMR processing : Topspin 4.1.13
View article: Larvicidal Activity of Momordica foetida (Cucurbitaceae), Gnidia glauca (Thymelaeaceae) and Vepris soyauxii (Rutaceae) Extracts on Anopheles gambiae Mosquitoes and their Acute Toxicity on Rats
Larvicidal Activity of Momordica foetida (Cucurbitaceae), Gnidia glauca (Thymelaeaceae) and Vepris soyauxii (Rutaceae) Extracts on Anopheles gambiae Mosquitoes and their Acute Toxicity on Rats Open
Background: The need to apply alternative strategies to control African malaria vectors such as Anopheles gambiae s.l. is extremely relevant. This study aimed at determining the larvicidal activity of 03 plants against Anopheles gambiae s.…
View article: Inhibition of prolyl oligopeptidase by flavonoids isolated from the roots of Allexis obanensis (Baker f.) Melch
Inhibition of prolyl oligopeptidase by flavonoids isolated from the roots of Allexis obanensis (Baker f.) Melch Open
Background: Prolyl oligopeptidase is a cytosolic serine peptidase that hydrolyzes peptides containing proline at the carboxy terminus of proline residues. It has been associated with several neurodegenerative diseases. Therefore, it is a t…
View article: ANTI-OBESITY EFFECTS OF THE METHANOL EXTRACT OF MOMORDICA FOETIDA (CUCURBITACEAE) IN MALE WISTAR RATS
ANTI-OBESITY EFFECTS OF THE METHANOL EXTRACT OF MOMORDICA FOETIDA (CUCURBITACEAE) IN MALE WISTAR RATS Open
Objective: This study was designed to evaluate the effect of the methanol extract of M. foetida (MEMf) on high fat diet-induced obese male rats.
Results: HFD induced an increase (P<0.05) in the body and liver weights and the relative abdo…
View article: Qualitative Analysis of Peptides and Biological Activities of Allexis cauliflora (Violaceae) Leaves
Qualitative Analysis of Peptides and Biological Activities of Allexis cauliflora (Violaceae) Leaves Open
Allexis cauliflora is a Cameroonian medicinal plant belonging to the violaceae family. It is used in traditional medicine to treat fever, syphilis and malaria. The aim of this study is to screen the peptides from the leaves of Allexis caul…
View article: Phytochemistry and Antioxidant Activities of the Methanolic Leaf Extract of Clerodendrum splendens (Lamiaceae)
Phytochemistry and Antioxidant Activities of the Methanolic Leaf Extract of Clerodendrum splendens (Lamiaceae) Open
This paper aimed at studying the antioxidant efficacy of the methanolic leaf extract of Clerodendrum splendens, a plant of the Lamiaceae family. Phytochemical tests carried out on extracts of Clerodendrum splendens leaves have been able to…