Dev Leibowitz
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View article: Evaluating the Combined Anticancer Response of Checkpoint Inhibitor Immunotherapy and FAP-Targeted Molecular Radiotherapy in Murine Models of Melanoma and Lung Cancer
Evaluating the Combined Anticancer Response of Checkpoint Inhibitor Immunotherapy and FAP-Targeted Molecular Radiotherapy in Murine Models of Melanoma and Lung Cancer Open
Immunotherapy has dramatically improved outcomes for some cancer patients; however, novel treatments are needed for more patients to achieve a long-lasting response. FAP-targeted molecular radiotherapy has shown efficacy in both preclinica…
View article: Preliminary efficacy of [90Y] DOTA-biotin-avidin radiotherapy against non-muscle invasive bladder cancer
Preliminary efficacy of [90Y] DOTA-biotin-avidin radiotherapy against non-muscle invasive bladder cancer Open
Purpose: Bladder cancer represents 3% of all new cancer diagnoses per year. We propose intravesical radionuclide therapy using the β-emitter 90 Y linked to DOTA-biotin-avidin ([ 90 Y]DBA) to deliver short-range radiation against non-muscle…