Dev Bukhsh Singh
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View article: Molecular docking and simulation analysis of nimbolide with poly-galacturonase from Aspergillus niger: Managing black mold disease for Allium cepa
Molecular docking and simulation analysis of nimbolide with poly-galacturonase from Aspergillus niger: Managing black mold disease for Allium cepa Open
Black mold disease is a major post-harvest issue in Allium cepa caused by Aspergillus niger. Therefore, it is of interest to describe the molecular docking and simulation analysis of poly-galacturonase protein from Aspergillus Niger that i…
View article: Cyber Security and International Law: Government Transparency and Accountability through E-Government & Political Implications
Cyber Security and International Law: Government Transparency and Accountability through E-Government & Political Implications Open
The paper tries to explain and elaborate on how cybersecurity will shift the course of diplomacy and how international law could influence the mode in which international legal interest is exercised. It also explores how powerful organizat…
View article: Deciphering the Electrostatic and Structural dynamics due to point Mutation in DNA gyrase leading to acquired Quinolone resistance in Mycobacterium tuberculosis
Deciphering the Electrostatic and Structural dynamics due to point Mutation in DNA gyrase leading to acquired Quinolone resistance in Mycobacterium tuberculosis Open
The structural bioinformatics analysis approach provides valuable information regarding the protein’s structure and function by analyzing the contribution of each and every amino acid residue present in its active site. Residue substitutio…
View article: Effect of Bio fertilizers with NPK Level on Vegetative Growth, Flowering and Flower Yield of F1 Hybrid (Pusa Basanti) of african marigold
Effect of Bio fertilizers with NPK Level on Vegetative Growth, Flowering and Flower Yield of F1 Hybrid (Pusa Basanti) of african marigold Open
An investigation was carried out to study effect of Biofertilizers with NPK levels on vegetative growth, flowering and flower yield of F1 hybrid ( Pusa Basanti) of African marigold (Targets erecta ) during the winter season 2008-2009 .The …
View article: Comprehensive analysis of non-synonymous SNPs related to Parkinson’s disease and molecular dynamics simulation of PRKN mutants
Comprehensive analysis of non-synonymous SNPs related to Parkinson’s disease and molecular dynamics simulation of PRKN mutants Open
Parkinson’s disease (PD) is associated with a mutation in the PRKN (Parkin RBR E3 Ubiquitin Protein Ligase). PRKN functions as maintaining dopamine (DA) neuronal homeostasis and homeostasis dysfunction, which play an important role in earl…
View article: Simulation studies, 3D QSAR and molecular docking on a point mutation of protein kinase B with flavonoids targeting ovarian Cancer
Simulation studies, 3D QSAR and molecular docking on a point mutation of protein kinase B with flavonoids targeting ovarian Cancer Open
Background Ovarian cancer is the world’s dreaded disease and its prevalence is expanding globally. The study of integrated molecular networks is crucial for the basic mechanism of cancer cells and their progression. During the present inve…
View article: Nutritional Significance and Antioxidant-Mediated Antiaging Effects of Finger Millet: Molecular Insights and Prospects
Nutritional Significance and Antioxidant-Mediated Antiaging Effects of Finger Millet: Molecular Insights and Prospects Open
Aging is a multifaceted process that is associated with progressive, lethal, and unalterable changes like damage to different molecules (DNA, proteins, and lipids), cells, tissues, and organs. It is an inevitable process but can be delayed…
View article: Computational Study of Lactucine and its Derivatives with Apoptosis Inducing Proteins of Various Pathways
Computational Study of Lactucine and its Derivatives with Apoptosis Inducing Proteins of Various Pathways Open
In the present computational study, we found that lactucin 15-oxalate a chemical component present in the cichorium intybus (chicory) has a potential apoptosis inducing effect in human leukemia cancer cell and may acts as an anticancer age…
View article: Simulation Studies 3D QSAR and Molecular Docking, on a Point Mutation of Protein Kinase B with Flavonoids Targeting Ovarian Cancer
Simulation Studies 3D QSAR and Molecular Docking, on a Point Mutation of Protein Kinase B with Flavonoids Targeting Ovarian Cancer Open
Cancer is the world’s dreaded disease and its prevalence is expanding globally. The study of integrated molecular networks is crucial for the basic mechanism of cancer cells and its progression. During the present investigation we have exa…
View article: Development of Flaxseed Fortified Synbiotic Flavoured Dahi (Yoghurt) Using Response Surface Methodology
Development of Flaxseed Fortified Synbiotic Flavoured Dahi (Yoghurt) Using Response Surface Methodology Open
Response surface methodology was employed to find out optimum proportions of flaxseed powder, mango pulp, synbiotic microcapsules to develop flaxseed fortified synbiotic mango Dahi. The quadratic model was fitted to antioxidant activity, f…
View article: Perspectives and challenges of tropical medicinal herbs and modern drug discovery in the current scenario
Perspectives and challenges of tropical medicinal herbs and modern drug discovery in the current scenario Open
Tropical diseases such as malaria, tuberculosis, trypanosomiasis, and leishmaniasis, account for a large number of deaths annually. Herbs are an excellent source of tropical medicines. Many advancements and discoveries have taken place in …
View article: Genetic Study on Biochemical Constituents in Blood Serum of Indian Native Uttara Fowl
Genetic Study on Biochemical Constituents in Blood Serum of Indian Native Uttara Fowl Open
The averages of blood glucose, TC, TG, LDL, HDL and VLDL were 221.43±2.55, 119.26±1.89, 255.16±15.52, 26.43±2.74, 42.45±1.50 and 44.83±5.58 mg/ dl respectively. The means of AST and ALT were 53.50±0.59 and 15.48±0.58 IU/L. The means of ACP…