Devin T. Corrigan
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View article: 418 Novel PD-1xKIR3DL3 bispecific antibodies take the brakes off T and NK cells
418 Novel PD-1xKIR3DL3 bispecific antibodies take the brakes off T and NK cells Open
View article: TOP CAR with TMIGD2 as a safe and effective costimulatory domain in CAR cells treating human solid tumors
TOP CAR with TMIGD2 as a safe and effective costimulatory domain in CAR cells treating human solid tumors Open
Chimeric antigen receptor (CAR)–T cell therapy shows impressive efficacy treating hematologic malignancies but requires further optimization in solid tumors. Here, we developed a TMIGD2 optimized potent/persistent (TOP) CAR that incorporat…
View article: Mucosal and systemic antigen-specific antibody responses correlate with protection against active tuberculosis in nonhuman primates
Mucosal and systemic antigen-specific antibody responses correlate with protection against active tuberculosis in nonhuman primates Open
View article: Recent advancements in the B7/CD28 immune checkpoint families: new biology and clinical therapeutic strategies
Recent advancements in the B7/CD28 immune checkpoint families: new biology and clinical therapeutic strategies Open
View article: Blockade of the immunosuppressive KIR2DL5/PVR pathway elicits potent human NK cell–mediated antitumor immunity
Blockade of the immunosuppressive KIR2DL5/PVR pathway elicits potent human NK cell–mediated antitumor immunity Open
Cancer immunotherapy targeting the TIGIT/PVR pathway is currently facing challenges. KIR2DL5, a member of the human killer cell, immunoglobulin-like receptor (KIR) family, has recently been identified as another binding partner for PVR. Th…
View article: Protocol for evaluating antitumor activity of KIR3DL3 blockade in an NK cell-based xenogeneic lung tumor model
Protocol for evaluating antitumor activity of KIR3DL3 blockade in an NK cell-based xenogeneic lung tumor model Open
View article: Monoclonal antibodies to lipoarabinomannan/arabinomannan – characteristics and implications for tuberculosis research and diagnostics
Monoclonal antibodies to lipoarabinomannan/arabinomannan – characteristics and implications for tuberculosis research and diagnostics Open
View article: Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes
Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes Open