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View article: Pore-forming activity of <i>S. pneumoniae</i> pneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin
Pore-forming activity of <i>S. pneumoniae</i> pneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin Open
Streptococcus pneumoniae, a common cause of community-acquired bacterial pneumonia, can cross the respiratory epithelial barrier to cause lethal septicemia and meningitis. S. pneumoniae pore-forming toxin pneumolysin (PLY) triggers robust …
View article: Pore-forming activity of<i>S. pneumoniae</i>pneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin
Pore-forming activity of<i>S. pneumoniae</i>pneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin Open
Streptococcus pneumoniae, a common cause of community-acquired bacterial pneumonia, can cross the respiratory epithelial barrier to cause lethal septicemia and meningitis. S. pneumoniae pore-forming toxin pneumolysin (PLY) triggers robust …
View article: Differential Response to the Course of Cryptosporidium parvum Infection and Its Impact on Epithelial Integrity in Differentiated versus Undifferentiated Human Intestinal Enteroids
Differential Response to the Course of Cryptosporidium parvum Infection and Its Impact on Epithelial Integrity in Differentiated versus Undifferentiated Human Intestinal Enteroids Open
Cryptosporidium is a leading cause of diarrhea and death in young children and untreated AIDS patients and causes waterborne outbreaks. Pathogenic mechanisms underlying diarrhea and intestinal dysfunction are poorly understood.
View article: Dynamic Python-Based Method Provides Quantitative Analysis of Intercellular Junction Organization During S. pneumoniae Infection of the Respiratory Epithelium
Dynamic Python-Based Method Provides Quantitative Analysis of Intercellular Junction Organization During S. pneumoniae Infection of the Respiratory Epithelium Open
Many respiratory pathogens compromise epithelial barrier function during lung infection by disrupting intercellular junctions, such as adherens junctions and tight junctions, that maintain intercellular integrity. This includes Streptococc…