Explanipedia

High transplant conversion rates with gemcitabine, dexamethasone and carboplatin (GDP)-based therapy in Relapsed/Refractory lymphoma: A real-world experience Open

L. Nair, Dhara Shah · 2025

Background Relapsed & refractory (R/R) disease imposes significant morbidity and mortality on lymphoma patients. Salvage chemotherapy to achieve complete remission (CR) followed by an Autologous Hematopoietic Cell Transplantation (auto-HCT…

Analytical validation and sequencing coverage studies suggest that performance of a liquid biopsy assay is tumor agnostic (DNA-is-DNA) Open

Wei Meng, R. Petry, Norberto Pantoja Galicia, Allison van den Hout, Jessie Z. Yu , et al. · 2025

Per regulatory and standard requirements (e.g., Clinical & Laboratory Standards Institute (CLSI) guidelines, United States Food and Drug Administration (FDA) correspondence), analytical validation (AV) for each companion diagnostic (CDx) b…

The mesopic negative response (MeNR): a novel approach to assess retinal ganglion cell function within the rod pathway Open

J. Jason McAnany, Jason C. Park, Pablo A. Barrionuevo, Dhara Shah, Thasarat S. Vajaranant , et al. · 2025

Evaluation of the role of helical CT in blunt abdominal trauma Open

Faisal M. Shaikh, Dhara Shah · 2024

Background: The majority of injuries are the result of blunt trauma. For these individuals, CT has emerged as the main diagnostic tool. The development of computer technology and slip ring gantry design has made it possible to scan much fa…

Abstract 1577 A Human Gut Microbial Sulfotransferase Modulates Concentrations of Acetaminophen Sulfate and Other Phenolic Sulfates Open

Rylee Close, S. Kremer, Madison Mitchem, Andrew Bellinghiere, Chad R. Borges , et al. · 2024

Sulfation is one of the two main phase II detoxification pathways in eukaryotes that transform non-polar compounds into hydrophilic metabolites. This process is catalyzed by sulfotransferases. Mammalian sulfotransferases use only 3'-phosph…

Effect of a Phytochemical formulation on Muscle fatigue, Energy, Recovery in Delayed Onset Muscle Soreness (DOMS), inflammation and Stress in Healthy Subjects: Results from a Randomized Placebo Controlled Study Open

Aurea Biolabs, Anupam Paliwal, Blake Kraemer, Dhara Shah, Ishita Basera , et al. · 2024

Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity Open

Maria Dichiara, Francesca Alessandra Ambrosio, Sang‐Min Lee, M. Carmen Ruiz‐Cantero, Jessica Lombino , et al. · 2023

The design and synthesis of a series of 2,7-diazaspiro[4.4]nonane derivatives as potent sigma receptor (SR) ligands, associated with analgesic activity, are the focus of this work. In this study, affinities at S1R and S2R were measured, an…

Modulation of ocular surface desiccation in a murine model by histatin-5 application Open

Marwan Ali, Dhara Shah, Terry G. Coursey, Sang‐Min Lee, Arun Balasubramaniam , et al. · 2022

Effectiveness of Different Sterilization Methods on Clinical Orthodontic Materials Open

Anil Ardeshna, Krupa Chavan, Anjana Prakasam, Dev Ardeshna, Dhara Shah , et al. · 2022

Background Orthodontic appliances such as wires and brackets received from manufacturers come unsterilized and may be contaminated with various microorganisms before being used in the mouth. In this study, we evaluated and identified the b…

Pediatric burkitt lymphoma: 5 years experience from a single tertiary care center in low-middle income country Open

Trupti Dhabale, Sangeeta Mudaliar, Minnie Bhodhanwala, Purva Kanvinde, Ritika Khurana , et al. · 2022

Teleconsultation in pediatric hematology-oncology practice – Dawning of a new era Open

Aekta Gupta, Ritika Khurana, Sanaa Khan, Suyog Nagare, Ajay Sharma , et al. · 2021

Transcranial doppler screening in patients with sickle cell anemia in tertiary care hospital Open

Dhara Shah, Ritika Khurana, Bharat Gala, Sanna Khan, Aekta Gupta , et al. · 2021

Baseline nutrition in pediatric cancer therapy: A potential game changer Open

Trupti Dhabale, Ritika Khurana, Amit Kumar, Purva Kanvinde, Vaibhav Chadha , et al. · 2021

Histatin-1 Attenuates LPS-Induced Inflammatory Signaling in RAW264.7 Macrophages Open

Sangmin Lee, Kyung‐No Son, Dhara Shah, Marwan Ali, Arun Balasubramaniam , et al. · 2021

Macrophages play a critical role in the inflammatory response to environmental triggers, such as lipopolysaccharide (LPS). Inflammatory signaling through macrophages and the innate immune system are increasingly recognized as important con…

Histatin‐1 is an endogenous ligand of the sigma‐2 receptor Open

Kyung‐No Son, Hyun Lee, Dhara Shah, Sushma Kalmodia, Ryan C. Miller , et al. · 2021

The Sigma‐2 receptor (S2R) (a.k.a TMEM97) is an important endoplasmic reticular protein involved in cancer, cholesterol processing, cell migration, and neurodegenerative diseases, including Niemann–Pick Type C. While several S2R pharmacolo…

Evolution of drug resistance in HIV protease Open

Dhara Shah, Christopher B. Freas, Irene T. Weber, Robert W. Harrison · 2020

A Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Saccharomyces boulardii in Infants and Children With Acute Diarrhea Open

Florian Mourey, Varun Sureja, Dharmeshkumar Kheni, Parthiv Shah, Devang Parikh , et al. · 2020

Aim: This study was designed to assess the efficacy and safety of Saccharomyces cerevisiae variant boulardii CNCM I-3799 ( S . boulardii CNCM I-3799) in the management of acute diarrhea in children. Methods: A total of 100 infants and chil…

A COMPARATIVE STUDY BETWEEN TWO MONITORING TECHNIQUES OF AWAKE BLIND NASAL INTUBATIONS IN CASES OF RESTRICTED MOUTH OPENING Open

Bipin K Shah, Dhara Shah, Hitesh Chelani, Krishna Shah, Sanjay Baldaniya , et al. · 2020

ORIGINAL ARTICLE A COMPARATIVE STUDY BETWEEN TWO MONITORING TECHNIQUES OF AWAKE BLIND NASAL INTUBATIONS IN CASES OF RESTRICTED MOUTH OPENING

Clinical efficacy of different dosage forms containing vitamin D: design and study outcomes of a randomized, comparative clinical trial Open

Nidhi Sapkal, Gaurav Chhaya, Milan Satya, Dhara Shah · 2020

Background: Different dosage forms of vitamin D like tablets, soft gelatin capsules, oral granules, powders, solutions and thin films are available. The objective of the present study was to evaluate and compare the clinic…

A Novel Wound Healing Peptide Open

Marwan Ali, Dhara Shah, Kyung‐No Son, Sushma Kalmodia, Arun Balasubramaniam , et al. · 2020

Murine corneal epithelial wound healing is enhanced by histatin-5 application Open

Kyung‐No Son, Dhara Shah, Sushma Kalmodia, Arun Balasubramaniam, Marwan Ali , et al. · 2020

Improvement in Murine Ocular Surface Parameters after Induction of Inflammation by Benzalkonium Chloride Open

Megan Helms, Vinay K. Aakalu, Dhara Shah, Sushma Kalmodia, Kyung‐No Son , et al. · 2020

ERK Activation is Necessary for Histatin-5 Induced Epithelial Wound healing Open

Sushma Kalmodia, Dhara Shah, Kyung‐No Son, Arun Balasubramaniam, Marwan Ali , et al. · 2020

Comparison of Cellular Cytotoxicity Induced by Dry Eye Conditions by Formulations of Cyclosporine. Open

Arun Balasubramaniam, Dhara Shah, Yongbeom Seo, Kyung‐No Son, Marwan Ali , et al. · 2020

Wound Healing Properties of Histatin-5 and Identification of a Functional Domain Required for Histatin-5-Induced Cell Migration Open

Dhara Shah, Kyung‐No Son, Sushma Kalmodia, Bao‐Shiang Lee, Marwan Ali , et al. · 2020

Histatin peptides are endogenous anti-microbial peptides that were originally discovered in the saliva. Aside from their broad anti-microbial properties, these peptides play an important role in multiple biological systems. Different membe…

Presence of Histatin-1 in Human Tears and Association with Aqueous Deficient Dry Eye Diagnosis: A Preliminary Study Open

Sushma Kalmodia, Kyung‐No Son, Dingcai Cao, Bao‐Shiang Lee, Bayasgalan Surenkhuu , et al. · 2019

The aims of this study were to determine if histatin-1 (H1) is present in normal human tears and whether tear levels of H1 varied between normal patients and those with aqueous deficient dry eye disease (ADDE). Patient samples were obtaine…

Histatins abrogate corneal epithelial toxicity Open

Vinay K. Aakalu, Marwan Ali, Dhara Shah, Sushma Kalmodia, Arun Kumar Balasubramaniam , et al. · 2018

Pertussis Toxin Sensitive Wound Healing Effects of Histatin Peptides in Corneal Epithelia Open

Dhara Shah, Kyung‐No Son, Sushma Kalmodia, Marwan Ali, Arun Balasubramaniam , et al. · 2018

Histatin peptide localization and effects on immune signaling in human corneal epithelium Open

Sushma Kalmodia, Dhara Shah, Kyung‐No Son, Arun Balasubramaniam, Marwan Ali , et al. · 2018

Developmental Gene Expression in Human Lacrimal Gland Open

Dhara Shah, Marwan Ali, Sowmya Parmeswaran, Subramanian Krishnakumar, Vinay K. Aakalu · 2017

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